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Isofebrifugine

PubChem CID: 9851693

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Compound Synonyms Isofebrifugine, isofebrifugin, 32434-44-9, CHEBI:6008, CHEMBL105789, alpha-Dichroine, Dichroine-alpha, C10698, NIOSH/HX7574000, SCHEMBL12033795, AKOS037515131, FS-7650, HX75740000, Q27106979
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 74.2
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1C(CC2CC3CCCCC3C2)CCC2CCCCC21
Np Classifier Class Quinazoline alkaloids
Deep Smiles O=cncncc6cccc6))))))))CCO)C[C@H][C@@H]O5)CCCN6
Heavy Atom Count 22.0
Classyfire Class Diazanaphthalenes
Scaffold Graph Node Level OC1C2CCCCC2NCN1CC1CC2NCCCC2O1
Classyfire Subclass Benzodiazines
Isotope Atom Count 0.0
Molecular Complexity 483.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name 3-[[(3aS,7aS)-2-hydroxy-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridin-2-yl]methyl]quinazolin-4-one
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 0.4
Gsk 4 400 Rule True
Molecular Formula C16H19N3O3
Scaffold Graph Node Bond Level O=c1c2ccccc2ncn1CC1CC2NCCCC2O1
Inchi Key YLYLCQRQSRDSQR-ADTLFGHVSA-N
Silicos It Class Soluble
Rotatable Bond Count 2.0
Synonyms isofebrifugine
Esol Class Soluble
Functional Groups CC(C)(O)OC, CNC, c=O, cn(c)C, cnc
Compound Name Isofebrifugine
Exact Mass 301.143
Formal Charge 0.0
Monoisotopic Mass 301.143
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 301.34
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C16H19N3O3/c20-15-11-4-1-2-5-12(11)18-10-19(15)9-16(21)8-13-14(22-16)6-3-7-17-13/h1-2,4-5,10,13-14,17,21H,3,6-9H2/t13-,14-,16?/m0/s1
Smiles C1C[C@H]2[C@H](CC(O2)(CN3C=NC4=CC=CC=C4C3=O)O)NC1
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Dichroa Febrifuga (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/10447961
  • 2. Outgoing r'ship FOUND_IN to/from Hydrangea Macrophylla (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/12820234