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Alkaloid B

PubChem CID: 98477

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Compound Synonyms Alkaloid B, 11.alpha.-Hydroxycephalotaxine, CEPHALOTAXINE,11-HYDROXY, Cephalotaxine, 15-hydroxy-, (1S,3aR)-1,5,6,8,9,14bbeta-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1alpha,9alpha-diol, 11alpha-Hydroxycephalotaxine, 4-methoxy-16,18-dioxa-10-azapentacyclo(11.7.0.02,6.06,10.015,19)icosa-1(20),4,13,15(19)-tetraene-3,12-diol, 4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraene-3,12-diol, 11-Hydroxycephalotaxine #, Cephalotaxine, 11-hydroxy-, (11.alpha.)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 71.4
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCC4CCCC45CCCC5C3CC2C1
Np Classifier Class Cephalotaxus alkaloids
Deep Smiles COC=CCCC5O))cccOCOc5cc9CCN%14CCC%17)))))O
Heavy Atom Count 24.0
Classyfire Class Cephalotaxus alkaloids
Scaffold Graph Node Level C1CC2C3CC4OCOC4CC3CCN3CCCC23C1
Isotope Atom Count 0.0
Molecular Complexity 554.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraene-3,12-diol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.4
Gsk 4 400 Rule True
Molecular Formula C18H21NO5
Scaffold Graph Node Bond Level C1=CC23CCCN2CCc2cc4c(cc2C3C1)OCO4
Prediction Swissadme 1.0
Inchi Key SZCHXNLVRKQEGO-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.5555555555555556
Rotatable Bond Count 1.0
Synonyms alkaloid b
Esol Class Soluble
Functional Groups CC=C(C)OC, CN(C)C, CO, c1cOCO1
Compound Name Alkaloid B
Prediction Hob Swissadme 1.0
Exact Mass 331.142
Formal Charge 0.0
Monoisotopic Mass 331.142
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 331.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.240281600000001
Inchi InChI=1S/C18H21NO5/c1-22-15-7-18-3-2-4-19(18)8-12(20)10-5-13-14(24-9-23-13)6-11(10)16(18)17(15)21/h5-7,12,16-17,20-21H,2-4,8-9H2,1H3
Smiles COC1=CC23CCCN2CC(C4=CC5=C(C=C4C3C1O)OCO5)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Cephalotaxus Fortunei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Cephalotaxus Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Jatropha Gossypiifolia (Plant) Rel Props:Reference:ISBN:9788172362461
  • 4. Outgoing r'ship FOUND_IN to/from Sarcococca Pruniformis (Plant) Rel Props:Reference:ISBN:9788187748090