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Norsanguinarine

PubChem CID: 97679

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Compound Synonyms Norsanguinarine, 522-30-5, Sanguinarine, 13-demethyl-, (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridine, 1,3-Dioxolo[i][1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine, 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene, NSC 143762, [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 1,3-Dioxolo(i)(1,3)dioxolo(4,5)benzo(1,2-c)phenanthridine, [1,3]Dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine, 5157-23-3, 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene, 5,7,18,20-tetraoxa-24-azahexacyclo(11.11.0.0^(2,10).0^(4,8).0^(14,22).0^(17,21))tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene, 5,7,18,20-tetraoxa-24-azahexacyclo(11.11.0.02,10.04,8.014,22.017,21)tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene, 13-Demethyl-Sanguinarine, CHEMBL4751586, SCHEMBL16125304, DTXSID90965891, CHEBI:179641, NSC143762, AKOS030535106, FS-8003, NSC-143762, HY-123077, NS00093944, [1,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 7,8-Bis(methylenedioxy)benzo[c]phenanthridine, 1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine, 2H,10H-[1,3]Benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine, 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0(2),(1)?.0?,?.0(1)?,(2)(2).0(1)?,(2)(1)]tetracosa-1(13),2(10),3,8,11,14(22),15,17(21),23-nonaene
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCC4C(CCC5C6CCCC6CCC54)C3CC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COccO5)cccc6)cccc6nccc6cccc6OCO5
Heavy Atom Count 24.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level C1OC2CC3CCC4C5CCC6OCOC6C5CNC4C3CC2O1
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 502.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene
Prediction Hob 1.0
Class Quinolines and derivatives
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 4.3
Superclass Organoheterocyclic compounds
Subclass Benzoquinolines
Gsk 4 400 Rule True
Molecular Formula C19H11NO4
Scaffold Graph Node Bond Level c1cc2c(cnc3c4cc5c(cc4ccc23)OCO5)c2c1OCO2
Prediction Swissadme 0.0
Inchi Key CNXVDVMAYXLWPD-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.1052631578947368
Logs -4.043
Rotatable Bond Count 0.0
State Solid
Logd 3.025
Synonyms (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-I)phenanthridine, 1,3-Dioxolo(I)(1,3)dioxolo(4,5)benzo(1,2-c)phenanthridine, 1,3-Dioxolo[I][1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine, 13-Demethyl-sanguinarine, 2,3, 7,8-Bis(methylenedioxy)benzo[c]phenanthridine, Dihydrosanguinarine, [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-I]phenanthridine, 13-Demethylsanguinarine, Demethylsanguinarine, N-Norsanguinarine, Norsanguinarine, norsanguinarine
Esol Class Moderately soluble
Functional Groups c1cOCO1, cnc
Compound Name Norsanguinarine
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 317.069
Formal Charge 0.0
Monoisotopic Mass 317.069
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 317.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -5.08386
Inchi InChI=1S/C19H11NO4/c1-2-12-11-3-4-15-19(24-9-21-15)14(11)7-20-18(12)13-6-17-16(5-10(1)13)22-8-23-17/h1-7H,8-9H2
Smiles C1OC2=C(O1)C3=CN=C4C(=C3C=C2)C=CC5=CC6=C(C=C54)OCO6
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Phenanthridines and derivatives
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Microstigma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Argemone Mexicana (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 3. Outgoing r'ship FOUND_IN to/from Chrozophora Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Eschscholzia Californica (Plant) Rel Props:Reference:ISBN:9770972795006
  • 5. Outgoing r'ship FOUND_IN to/from Fumaria Indica (Plant) Rel Props:Reference:ISBN:9788185042138
  • 6. Outgoing r'ship FOUND_IN to/from Fumaria Vaillantii (Plant) Rel Props:Reference:ISBN:9788185042114
  • 7. Outgoing r'ship FOUND_IN to/from Larix Decidua (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Meconopsis Horridula (Plant) Rel Props:Source_db:npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Senna Tora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Swertia Mussotii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all