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Uzarigenin

PubChem CID: 92760

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Compound Synonyms Uzarigenin, 466-09-1, Urarigenin, Odorigeni, K9ZR7LI283, (3.beta.,5.alpha.)-3,14-Dihydroxycard-20(22)-enolide, Card-20(22)-enolide, 3,14-dihydroxy-, (3.beta.,5.alpha.)-, 4-18-00-01470 (Beilstein Handbook Reference), EINECS 207-373-0, NSC 119993, BRN 0095446, UNII-K9ZR7LI283, 3-beta-14-beta-5-Allo-cardenolid [German], NSC-119993, NSC-277290, 3beta,14-Dihydroxy-5alpha-card-20(22)-enolide, 3-beta-14-beta-5-Allo-cardenolid, 3-beta,14-Dihydroxy-5-alpha-card-20(22)-enolide, ODORIGENIN, ODORIGENIN B, Uzarigenin (Odorigenin), UZARIGENIN [MI], NSC 119993, NSC 277290, Odorigeni, Urarigenin, 5alpha-Card-20(22)-enolide, 3beta,14-dihydroxy-, 5-alpha-Card-20(22)-enolide, 3-beta,14-dihydroxy-, CHEMBL109863, SCHEMBL1152953, XZTUSOXSLKTKJQ-CIXPXFMPSA-N, Card-20(22)-enolide, 3,14-dihydroxy-, (3beta,5alpha)-, DTXSID901017013, HY-N1107, AKOS040762476, FS-9903, FU42614, NCGC00384854-01, 3,14-Dihydroxycard-20(22)-enolide #, 3-.beta.-14-.beta.-5-Allo-cardenolid, CS-0016395, NS00080556, Q27282143, 5.alpha.-Card-20(22)-enolide, 3.beta.,14-dihydroxy-, NCGC00384854-01_C23H34O4_Card-20(22)-enolide, 3,14-dihydroxy-, (3beta,5alpha)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 66.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CCCCC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles O[C@H]CC[C@][C@H]C6)CC[C@@H][C@@H]6CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C)))))))))C
Heavy Atom Count 27.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 686.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id Q16236, P84022, O75496, Q99700, P43220, Q9NUW8, Q06710, O75874, n.a.
Iupac Name 3-[(3S,5S,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Target Id NPT1283
Xlogp 2.6
Gsk 4 400 Rule True
Molecular Formula C23H34O4
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Prediction Swissadme 1.0
Inchi Key XZTUSOXSLKTKJQ-CIXPXFMPSA-N
Silicos It Class Soluble
Fcsp3 0.8695652173913043
Logs -4.399
Rotatable Bond Count 1.0
Logd 3.631
Synonyms uzarigenin
Esol Class Soluble
Functional Groups CC1=CC(=O)OC1, CO
Compound Name Uzarigenin
Prediction Hob Swissadme 0.0
Exact Mass 374.246
Formal Charge 0.0
Monoisotopic Mass 374.246
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 374.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.759230200000001
Inchi InChI=1S/C23H34O4/c1-21-8-5-16(24)12-15(21)3-4-19-18(21)6-9-22(2)17(7-10-23(19,22)26)14-11-20(25)27-13-14/h11,15-19,24,26H,3-10,12-13H2,1-2H3/t15-,16-,17+,18-,19+,21-,22+,23-/m0/s1
Smiles C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

  • 1. Outgoing r'ship FOUND_IN to/from Anemone Narcissiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Asclepias Curassavica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Calotropis Gigantea (Plant) Rel Props:Source_db:npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Calotropis Procera (Plant) Rel Props:Reference:ISBN:9788172361150
  • 5. Outgoing r'ship FOUND_IN to/from Cascabela Thevetia (Plant) Rel Props:Reference:ISBN:9788172363093
  • 6. Outgoing r'ship FOUND_IN to/from Cryptotaenia Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Hyperbaena Columbica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Nerium Oleander (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/19319871
  • 9. Outgoing r'ship FOUND_IN to/from Pergularia Daemia (Plant) Rel Props:Reference:ISBN:9788190595216
  • 10. Outgoing r'ship FOUND_IN to/from Rhododendron Farrerae (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Toxicodendron Succedaneum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Viburnum Grandifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all