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(-)-Verapamil

PubChem CID: 92305

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Compound Synonyms (-)-verapamil, 36622-29-4, (S)-VERAPAMIL, (S)-(-)-verapamil, (S) Verapamil, (-)-(S)-verapamil, CHEMBL36148, (S)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile, CHEBI:77736, (2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile, 9P7619E627, (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, (-)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile, s-verapamil, verapamil-s, 4YH, Tocris-0654, starbld0017717, Lopac-V-4629, CAS-152-11-4, NCIMech_000868, VERAPAMIL, (-)-, BIDD:GT0587, SCHEMBL14874635, SGTNSNPWRIOYBX-MHZLTWQESA-N, DTXSID301017708, UNII-9P7619E627, VERAPAMIL (S)-FORM [MI], 2-(3,4-dimethoxy-phenyl)-5-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino}-2-isopropyl-pentanenitrile, EINECS 253-133-3, BDBM50005628, NCGC00016083-01, NCGC00016083-02, NCGC00016083-03, NCGC00016083-12, NCGC00016412-01, NCGC00024710-01, NCGC00686699-01, Q27147328, (-)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-(3,4-Dimethoxy-phenyl)-5-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino}-2-isopropyl-pentanenitrile(verapamil), BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)-, BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, (S)-, Benzeneacetonitrile, alpha-(3((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha(1-methylethyl)-, (alpha,S)-
Topological Polar Surface Area 64.0
Hydrogen Bond Donor Count 0.0
Heavy Atom Count 33.0
Isotope Atom Count 0.0
Molecular Complexity 606.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id n.a., P08183, P33527, P16473, P33261, P28482, P15917, P08482, P08684, P11712, O15296, P05177, O94782, Q99700, Q9NUW8
Iupac Name (2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
Prediction Hob 0.0
Target Id NPT668, NPT210, NPT213, NPT282, NPT109, NPT212, NPT208
Xlogp 3.8
Molecular Formula C27H38N2O4
Prediction Swissadme 0.0
Inchi Key SGTNSNPWRIOYBX-MHZLTWQESA-N
Fcsp3 0.5185185185185185
Logs -3.523
Rotatable Bond Count 13.0
Logd 3.132
Compound Name (-)-Verapamil
Prediction Hob Swissadme 0.0
Exact Mass 454.283
Formal Charge 0.0
Monoisotopic Mass 454.283
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 454.6
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Esol -4.45737910909091
Inchi InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/t27-/m0/s1
Smiles CC(C)[C@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
Nring 2.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Piper Nigrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all