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Tylophorine

PubChem CID: 92114

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Compound Synonyms Tylophorine, 482-20-2, Tylophorin, (+)-(S)-Tylophorine, UNII-O41630Y8V3, 2,3,6,7-Tetramethoxyphenanthro(9,10:6,7')indolizidine, NSC 76387, NSC-76387, NSC-717335, O41630Y8V3, TYLOPHORINE, (+)-, NSTP-0G01, CHEBI:9786, (+)-Tylophorine, (13aS)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine, (S)-9,11,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo(f,h)pyrrol o(1,2-b)isoquinoline, (13AS)-9,11,12,13,13A,14-HEXAHYDRO-2,3,6,7-TETRAMETHOXYDIBENZO(F,H)PYRROLO(1,2-B)ISOQUINOLINE, (S)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline, (S)-9,11,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo(f,h)pyrrolo(1,2-b)isoquinoline, DIBENZO(F,H)PYRROLO(1,2-B)ISOQUINOLINE, 9,11,12,13,13A,14-HEXAHYDRO-2,3,6,7-TETRAMETHOXY-, (13AS)-, Dibenzo(f,h)pyrrolo(1,2-b)isoquinoline, 9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, (S)-, Dibenzo[f,2-b]isoquinoline, 9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, (S)-, (S)-9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxydibenzo[f,h]pyrrol o(1,2-b)isoquinoline, (S)-9,11,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline, S(+)-Tylophorine, TYLOPHORINE [MI], SCHEMBL523625, CHEMBL250426, DTXSID30964025, GLXC-04594, NSC76387, NSC717335, AKOS027326841, NCI60_040526, NCI60_041685, DB-224813, HY-122324, NS00093881, Q27108498, 2,6,7-Tetramethoxyphenanthro[9,10:6',7']indolizidine, 2,3,6,7-Tetramethoxy-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline, 9,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline, Dibenzo[f,2-b]isoquinoline, 9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, Dibenzo[f,2-b]isoquinoline,9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, (13aS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3C4CCCCC4C4CCCCC4C3CC2C1
Np Classifier Class Indolizidine alkaloids
Deep Smiles COccccC[C@@H]CCCN5Cc9ccc%13cc%17OC)))))cccc6)OC)))OC
Heavy Atom Count 29.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level C1CCC2C(C1)C1CCCCC1C1CN3CCCC3CC21
Classyfire Subclass Phenanthroindolizidines
Isotope Atom Count 0.0
Molecular Complexity 573.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (13aS)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 4.7
Gsk 4 400 Rule False
Molecular Formula C24H27NO4
Scaffold Graph Node Bond Level c1ccc2c(c1)c1c(c3ccccc32)CN2CCCC2C1
Inchi Key SSEUDFYBEOIWGF-AWEZNQCLSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 4.0
Synonyms 2,3,6,7-tetramethoxy-phenanthro [9,10,6,7] indolizidine (tylophorine), 2,3,6,7-tetramethoxy-phenanthro [9,10_6,7] indolizidine (tylophorine), tylophorine
Esol Class Moderately soluble
Functional Groups CN(C)C, cOC
Compound Name Tylophorine
Exact Mass 393.194
Formal Charge 0.0
Monoisotopic Mass 393.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 393.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C24H27NO4/c1-26-21-9-16-15-8-14-6-5-7-25(14)13-20(15)19-12-24(29-4)23(28-3)11-18(19)17(16)10-22(21)27-2/h9-12,14H,5-8,13H2,1-4H3/t14-/m0/s1
Smiles COC1=C(C=C2C(=C1)C3=C(CN4CCC[C@H]4C3)C5=CC(=C(C=C52)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

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