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methyl (1R,15R,17S,18R)-17-ethyl-7-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate

PubChem CID: 90680628

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Compound Synonyms CHEMBL3286767
Topological Polar Surface Area 120.0
Hydrogen Bond Donor Count 3.0
Heavy Atom Count 54.0
Isotope Atom Count 0.0
Molecular Complexity 1480.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name methyl (1R,15R,17S,18R)-17-ethyl-7-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
Prediction Hob 0.0
Xlogp 5.2
Molecular Formula C44H54N4O6
Prediction Swissadme 0.0
Inchi Key DLGUNUQWWMZZFF-MNNHJPFTSA-N
Fcsp3 0.5454545454545454
Logs -4.67
Rotatable Bond Count 8.0
Logd 4.685
Compound Name methyl (1R,15R,17S,18R)-17-ethyl-7-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
Prediction Hob Swissadme 0.0
Exact Mass 734.404
Formal Charge 0.0
Monoisotopic Mass 734.404
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 734.9
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 1.0
Esol -7.391282266666667
Inchi InChI=1S/C44H54N4O6/c1-7-25-15-24-20-43(41(50)53-5)39-28(13-14-48(21-24)40(25)43)29-16-30(36(52-4)19-35(29)46-39)31-17-33-26(8-2)22-47(3)37(44(33,23-49)42(51)54-6)18-32-27-11-9-10-12-34(27)45-38(31)32/h8-12,16,19,24-25,31,33,37,40,45-46,49H,7,13-15,17-18,20-23H2,1-6H3/b26-8-/t24-,25+,31+,33-,37+,40-,43+,44+/m1/s1
Smiles CC[C@H]1C[C@@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC(=C(C=C45)[C@@H]6C[C@@H]7/C(=C\C)/CN([C@H]([C@@]7(CO)C(=O)OC)CC8=C6NC9=CC=CC=C89)C)OC)C(=O)OC
Nring 10.0
Defined Bond Stereocenter Count 1.0