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Maltol

PubChem CID: 8369

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Compound Synonyms MALTOL, 118-71-8, 3-Hydroxy-2-methyl-4-pyrone, 3-Hydroxy-2-methyl-4H-pyran-4-one, Larixinic acid, Palatone, Talmon, Larixic acid, Vetol, Veltol, Corps praline, 4H-Pyran-4-one, 3-hydroxy-2-methyl-, 3-hydroxy-2-methylpyran-4-one, 2-Methyl pyromeconic acid, 2-Methylpyromeconic acid, 2-Methyl-3-hydroxypyrone, 2-Methyl-3-hydroxy-4-pyrone, Maltol (natural), 3-Hydroxy-2-methyl-gamma-pyrone, 2-Methyl-3-oxy-gamma-pyrone, FEMA No. 2656, MFCD00006578, 3-Hydroxy-2-methylpyrone, 3-Hydroxy-2-methyl-pyran-4-one, Maltol [NF], NSC 2829, CCRIS 3467, Ins no.636, NSC-2829, EINECS 204-271-8, Ins-636, UNII-3A9RD92BS4, NSC-404458, BRN 0112169, 3A9RD92BS4, 2-methyl-3-hydroxy-4-pyranone, 3-Hydroxy-2-methyl-4-pyranone, DTXSID0025523, CHEBI:69438, AI3-18547, NSC2829, 3-Hydroxy-2-methyl-1,4-pyrone, MALTOL [FHFI], MALTOL [FCC], 3-Hydroxy-2-methyl-.gamma.-pyrone, MALTOL [II], MALTOL [MI], MALTOL [USP-RS], MALTOL [MART.], MLS000069412, DTXCID305523, E-636, HSDB 8320, 5-18-01-00114 (Beilstein Handbook Reference), 2-methyl-3-hydroxy-4H-pyran-4-one, 5-Hydroxy-6-methyl-4H-pyran-4-one, Maltol (3-Hydroxy-2-methyl-4-pyrone), E636, SMR000059093, MALTOL (USP-RS), MALTOL (II), MALTOL (MART.), WLN: T6O DVJ B1 CQ, CAS-118-71-8, methyl maltol, Laricinic acid, Laxarinic Acid, Maltol (Standard), 3-Hydroxy-2-methyl-4-pyrone, 3-Hydroxy-2-methyl-pyran-4-one, Maltol, Deferiprone Impurity B, 2Methyl3hydroxypyrone, 2Methyl3oxygammapyrone, 2Methyl3hydroxy4pyrone, 2Methylpyromeconic acid, 3Hydroxy2methyl4pyrone, Spectrum_001419, Opera_ID_338, SpecPlus_000443, 2Methyl pyromeconic acid, 2Methyl3hydroxypyran4one, 3Hydroxy2methyl4pyranone, MALTOL [INCI], Spectrum2_001795, Spectrum3_001351, Spectrum4_001871, Spectrum5_000462, 3Hydroxy2methylgammapyrone, bmse000538, 3Hydroxy2methyl4Hpyran4one, Maltol, analytical standard, SCHEMBL4815, 3-Hydroxy-2-pyran-4-one, BSPBio_003161, KBioGR_002365, KBioSS_001899, SPECTRUM310025, MLS001424145, MLS002415738, 3-Hydroxy-2-methyl-g-pyrone, CHEMBL31422, DivK1c_006539, 3-hydroxy-2-methylpyr-4-one, 4HPyran4one, 3hydroxy2methyl, SPBio_001749, INS No. 636, QSPL 180, 2-methyl-3-hydroxypyran-4-one, 2-Methyl-3-oxy-.gamma.-pyrone, 3-hydroxy-2-methyl-4-oxopyrane, 3-hydroxyl-2-methyl-4-pyranone, FEMA 2656, KBio1_001483, KBio2_001899, KBio2_004467, KBio2_007035, KBio3_002381, XPCTZQVDEJYUGT-UHFFFAOYSA-, 3-hydroxy-2-methyl-gamma -pyrone, HMS2052K09, HMS3394K09, KUC106764N, HY-W012788R, STR01642, Tox21_202215, Tox21_300118, BBL011669, BDBM50227434, CCG-38443, Maltol, natural, >=98.5%, FG, NSC404458, s4940, STK801686, Maltol, >=99.0%, FCC, FG, 3-Hydroxy-2-methyl-4-pyrone, 99%, AKOS005607790, CS-W013504, FM04338, HY-W012788, NC00350, PS-4578, SDCCGMLS-0066563.P001, NCGC00091223-01, NCGC00091223-02, NCGC00091223-03, NCGC00091223-04, NCGC00091223-05, NCGC00178231-01, NCGC00254046-01, NCGC00259764-01, BP-11468, KSC-11-228-8, NCI60_002320, SY011358, DB-002512, M0673, NS00012803, EN300-93557, Q420648, SR-01000712383, SR-01000712383-3, BRD-K40619305-001-12-1, Flavor and Extract Manufacturers' Association No. 2656, Z1255382969, Maltol, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3, 204-271-8
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCCC1
Np Classifier Class 4-pyrone derivatives
Deep Smiles O=cccocc6O))C
Heavy Atom Count 9.0
Classyfire Class Pyrans
Description Found in chicory, roasted malt, breads, milk, heated butter, uncured smoked pork, cocoa, coffee, roasted barley, roasted peanuts, roasted filbert, soybean etc. Flavour enhancer and flavouring agent Maltol is a naturally occurring organic compound that is used primarily as a flavor enhancer. It is found in the bark of larch tree, in pine needles, and in roasted malt (from which it gets its name). Because it has the odor of cotton candy and caramel, maltol is used to impart a sweet aroma to fragrances. Maltol's sweetness adds to the odor of freshly baked bread, and is used as a flavor enhancer (E number E636) in breads and cakes. Maltol is a biomarker for the consumption of soy beans and other soy products.
Scaffold Graph Node Level OC1CCOCC1
Classyfire Subclass Pyranones and derivatives
Isotope Atom Count 0.0
Molecular Complexity 200.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q04760, P02545, B2RXH2, Q9F4F7, P09917, P22894, P08254, P29477, O42713, P08253, P15917, P03956, P14780, O75164, Q96KQ7, Q9UIF8, n.a., Q9Y6L6, Q9NPD5, Q03431, P03433, P10275, Q16236
Iupac Name 3-hydroxy-2-methylpyran-4-one
Prediction Hob 1.0
Class Pyrans
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT1566, NPT483, NPT48
Xlogp 0.4
Superclass Organoheterocyclic compounds
Subclass Pyranones and derivatives
Gsk 4 400 Rule True
Molecular Formula C6H6O3
Scaffold Graph Node Bond Level O=c1ccocc1
Prediction Swissadme 0.0
Inchi Key XPCTZQVDEJYUGT-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.1666666666666666
Logs -0.979
Rotatable Bond Count 0.0
State Solid
Logd 0.431
Synonyms 2-Hydroxy-3-methyl-4H-pyran-4-one, 2-Methyl pyromeconic acid, 2-Methyl-3-hydroxy-4-pyranone, 2-Methyl-3-hydroxy-4-pyrone, 2-Methyl-3-hydroxypyrone, 2-Methyl-3-oxy-gamma-pyrone, 3-Hydroxy-2-methyl-1,4-pyrone, 3-Hydroxy-2-methyl-4-pyranone, 3-Hydroxy-2-methyl-4-pyrone, 3-Hydroxy-2-methyl-4H-pyran-4-one, 3-Hydroxy-2-methyl-g-pyrone, 3-Hydroxy-2-methyl-gamma-pyrone, 3-Hydroxy-2-methylpyran-4-one, 3-Hydroxy-2-methylpyrone, 3-Hydroxy-2-pyran-4-one, 4H-Pyran-4-one, 3-hydroxy-2-methyl-, 5-Hydroxy-6-methyl-4H-pyran-4-one, FEMA 2656, Laricinic acid, Larixic acid, Larixinic acid, Maltol, Palatone, Talmon, Veltol, Vetol, e636, 3-hydroxy-2-methyl-4h-pyran-4-one, maltol, maltol⁄
Substituent Name Pyranone, Heteroaromatic compound, Cyclic ketone, Oxacycle, Hydrocarbon derivative, Organooxygen compound, Aromatic heteromonocyclic compound
Esol Class Very soluble
Functional Groups c=O, cO, coc
Compound Name Maltol
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 126.032
Formal Charge 0.0
Monoisotopic Mass 126.032
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 126.11
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 True
Esol 0.2014784666666669
Inchi InChI=1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3
Smiles CC1=C(C(=O)C=CO1)O
Nring 1.0
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Pyranones and derivatives
Np Classifier Superclass Cyclic polyketides

  • 1. Outgoing r'ship FOUND_IN to/from Abies Balsamea (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2012.10644040
  • 2. Outgoing r'ship FOUND_IN to/from Angelica Acutiloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Angelica Gigas (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Angelica Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Annona Cherimola (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.3292
  • 6. Outgoing r'ship FOUND_IN to/from Bassia Scoparia (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2012.10644076
  • 7. Outgoing r'ship FOUND_IN to/from Bolbostemma Paniculatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Capsicum Annuum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Coffea Arabica (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.3517
  • 10. Outgoing r'ship FOUND_IN to/from Coffea Canephora (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.3517
  • 11. Outgoing r'ship FOUND_IN to/from Colocasia Esculenta (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.1998.9700849
  • 12. Outgoing r'ship FOUND_IN to/from Cordyceps Sinensis (Plant) Rel Props:Source_db:npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Crocus Sativus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Daphne Oleoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Delphinium Denudatum (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/9170290
  • 16. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Glabra (Plant) Rel Props:Reference:ISBN:9780896038776; ISBN:9788172362300
  • 17. Outgoing r'ship FOUND_IN to/from Ipomoea Batatas (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2013.809320
  • 18. Outgoing r'ship FOUND_IN to/from Liriope Muscari (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Ludwigia Octovalvis (Plant) Rel Props:Reference:ISBN:9789327275590
  • 20. Outgoing r'ship FOUND_IN to/from Macrothelypteris Oligophlebia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 21. Outgoing r'ship FOUND_IN to/from Marsdenia Tinctoria (Plant) Rel Props:Source_db:npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Maytenus Heterophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Ophiopogon Japonicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Panax Ginseng (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Panax Notoginseng (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Panax Quinquefolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Persicaria Bistorta (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2012.10662600
  • 28. Outgoing r'ship FOUND_IN to/from Polyalthia Nemoralis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Pterocarpus Indicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 30. Outgoing r'ship FOUND_IN to/from Quercus Robur (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/14664527
  • 31. Outgoing r'ship FOUND_IN to/from Robinia Pseudoacacia (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2017.1329670
  • 32. Outgoing r'ship FOUND_IN to/from Rubia Wallichiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Rubus Idaeus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 34. Outgoing r'ship FOUND_IN to/from Sagittaria Sagittifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Vigna Angularis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 36. Outgoing r'ship FOUND_IN to/from Vigna Umbellata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 37. Outgoing r'ship FOUND_IN to/from Vigna Umbeuata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all