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2-Methylbutanoic acid

PubChem CID: 8314

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Compound Synonyms 2-Methylbutanoic acid, 2-METHYLBUTYRIC ACID, 116-53-0, DL-2-Methylbutyric acid, Butanoic acid, 2-methyl-, Ethylmethylacetic acid, 2-Methyl butyric acid, 600-07-7, Carbomer 934, Methylethylacetic acid, 2-Methybutyric acid, Active valeric acid, Butyric acid, 2-methyl-, alpha-Methylbutyric acid, 9007-16-3, Methylbutyric acid, (+/-)-2-Methylbutyric acid, 2-methyl-butanoic acid, FEMA No. 2695, alpha-methyl butyric Acid, NSC 7304, 2-methyl-butyric acid, PX7ZNN5GXK, MFCD00002669, .alpha.-Methylbutyric acid, DL-2-Methyl-d3-butyricAcid, DTXSID5021621, CHEBI:37070, NSC-7304, Synthalen M, Acrypol 934, Carbopol 934, DTXCID301621, Valeric acid, active, Carbomer 934 (Technical Grade), Butanoic acid, methyl-, Methylbutyricacid, 2-Methylbutyric acid (VAN), CAS-116-53-0, Carbopol 974P, 2-Methylbutyric acid (natrual), (+)-2-methylbutanoic acid, UNII-PX7ZNN5GXK, EINECS 204-145-2, EINECS 209-982-7, (R)-2-Methylbutyric Acid-d3, (1)-2-Methylbutyric acid, BRN 1098537, AI3-24202, MFCD09029093, Ethylmethylacetate, 2-Ethylpropionate, 2-Methyl Butyrate, 2-METHYLBUTANOIC ACID (DL), 2-Methylbutanoicacid, Pokty(acrylic acid), DL-2-Methylbutyrate, 2-Ethylpropionic acid, D-2-Methyl Butyrate, DL-2-Methy Butyrate, butane-2-carboxylic acid, rac-2-methylbutanoic acid, D-2-Methyl Butyric acid, DL-2-Methy Butyric acid, (+/-)-2-Methylbutyrate, EC 204-145-2, SCHEMBL49960, 2-Methyl-Butyric Acid Anion, 2-Methylbutyric acid, 98%, (RS)-2-methyl-butyric acid, 4-02-00-00889 (Beilstein Handbook Reference), MLS001055480, Carbomer 934 [USAN:NF], CHEMBL1160012, NSC7304, (.+/-.)-2-Methylbutanoic acid, HMS2270O06, 2-METHYLBUTYRIC ACID, DL-, 1346617-08-0, 2-METHYLBUTYRIC ACID [FCC], 2-METHYLBUTYRIC ACID [FHFI], Tox21_201807, Tox21_303584, LMFA01020072, 2-Methylbutyric acid, >=98%, FG, Butanoic acid, 2-methyl-, (+ -), DL-.ALPHA.-METHYLBUTYRIC ACID, AKOS000121120, AKOS016843247, CS-W001942, FC44408, SB47880, NCGC00090971-01, NCGC00090971-02, NCGC00257513-01, NCGC00259356-01, 2-Methylbutyric acid, analytical standard, FM159331, PD041098, SMR000112113, SY115833, Methyl-2 Butyric Acid (Optically Active), DB-003300, M0181, NS00007338, EN300-27063, C18319, Q209433, (+/-)-2-Methylbutyric acid, natural, >=98%, FG, F0001-0289, Z237374874, (2R)-(-)-2-methylbutyric acid, R)-(-)-2-methylbutanoic acid
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Np Classifier Class Branched fatty acids
Deep Smiles CCC=O)O))CC
Heavy Atom Count 7.0
Classyfire Class Fatty acyls
Description Ethylmethylacetic acid is a carboxylic acid found in low amounts in normal humans (PMID 3372640) It has been described in the urine of individuals with 2-ethylhydracrylic aciduria associated with short/branched-chain acyl-CoA dehydrogenase deficiency (due to ACADSB gene mutations, OMIM 600301) (PMID 15615815) [HMDB]
Classyfire Subclass Fatty acids and conjugates
Isotope Atom Count 0.0
Molecular Complexity 68.5
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22309, Q7Z4W1, Q8VC69, Q80UJ1, Q13148
Iupac Name 2-methylbutanoic acid
Prediction Hob 1.0
Class Fatty Acyls
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.2
Superclass Lipids and lipid-like molecules
Subclass Fatty acids and conjugates
Gsk 4 400 Rule True
Molecular Formula C5H10O2
Prediction Swissadme 0.0
Inchi Key WLAMNBDJUVNPJU-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.8
Logs -0.35
Rotatable Bond Count 2.0
State Solid
Logd 2.241
Synonyms (+/-)-2-methylbutyrate, (+/-)-2-methylbutyric acid, 2-Ethylpropanoic acid, 2-Ethylpropionate, 2-Ethylpropionic acid, 2-Methybutyrate, 2-Methybutyric acid, 2-Methyl butyrate, 2-Methyl butyric acid, 2-Methyl-n-butyric acid, 2-Methylbutanoate, 2-Methylbutanoic acid, 2-Methylbutyrate, 2-Methylbutyric acid, a-Methyl butyrate, a-Methyl butyric acid, a-Methylbutyrate, a-Methylbutyric acid, Active valeric acid, alpha-Methyl butyrate, alpha-Methyl butyric acid, alpha-Methyl-n-butyric acid, alpha-Methylbutyrate, alpha-Methylbutyric acid, Butane-2-carboxylate, Butane-2-carboxylic acid, Butyric acid, 2-methyl- (6CI,8CI), Butyric acid, alpha-methyl- (3CI), D-2-Methyl butyrate, D-2-Methyl butyric acid, DL-2-Methy butyrate, DL-2-Methy butyric acid, DL-2-Methylbutyrate, Ethylmethylacetate, Ethylmethylacetic acid, FEMA 2695, Methylethylacetate, Methylethylacetic acid, α-methyl butyrate, α-methyl butyric acid, α-methylbutyrate, α-methylbutyric acid, Α-methyl butyrate, Α-methyl butyric acid, Α-methylbutyrate, Α-methylbutyric acid, DL-2-Methylbutyric acid, 2-Methylbutyrate, (+-)-isomer, 2-Methylbutyrate, sodium salt, RS-2-Methylbutyrate, 2-methyl butanoic acid, 2-methyl-butanoic-acid, 2-methyl-butyric-acid, 2-methylbutanoic acid, 2-methylbutyrate, 2-methylbutyric acid, 2-methylbutyricacid, methylethyl acetic acid, methylethylacetic acid
Substituent Name Methyl-branched fatty acid, Monocarboxylic acid or derivatives, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aliphatic acyclic compound
Esol Class Very soluble
Functional Groups CC(=O)O
Compound Name 2-Methylbutanoic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 102.068
Formal Charge 0.0
Monoisotopic Mass 102.068
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 102.13
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic acyclic compounds
Lipinski Rule Of 5 True
Esol -1.0846245999999997
Inchi InChI=1S/C5H10O2/c1-3-4(2)5(6)7/h4H,3H2,1-2H3,(H,6,7)
Smiles CCC(C)C(=O)O
Nring 0.0
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Methyl-branched fatty acids
Np Classifier Superclass Fatty Acids and Conjugates

  • 1. Outgoing r'ship FOUND_IN to/from Angelica Acutiloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Angelica Archangelica (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2001.9699689
  • 3. Outgoing r'ship FOUND_IN to/from Angelica Gigas (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Angelica Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Arctium Lappa (Plant) Rel Props:Source_db:fooddb_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Argania Spinosa (Plant) Rel Props:Reference:https://doi.org/10.1177/1934578x1000500626
  • 7. Outgoing r'ship FOUND_IN to/from Arnebia Euchroma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Arnebia Guttata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Capsicum Annuum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Capsicum Frutescens (Plant) Rel Props:Source_db:fooddb_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Carthamus Tinctorius (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Cassia Grandis (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2010.9700409
  • 13. Outgoing r'ship FOUND_IN to/from Cedrus Libani (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2000.9712210
  • 14. Outgoing r'ship FOUND_IN to/from Cinnamomum Aromaticum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Cinnamomum Cassia (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 16. Outgoing r'ship FOUND_IN to/from Coffea Arabica (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2014.977580
  • 17. Outgoing r'ship FOUND_IN to/from Coffea Canephora (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2014.977580
  • 18. Outgoing r'ship FOUND_IN to/from Elettaria Cardamomum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Elsholtzia Ciliata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Eruca Vesicaria (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1883
  • 21. Outgoing r'ship FOUND_IN to/from Fagopyrum Esculentum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Foeniculum Vulgare (Plant) Rel Props:Source_db:npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Fragaria Vesca (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.3095
  • 24. Outgoing r'ship FOUND_IN to/from Gardenia Jasminoides (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.1996.9700609
  • 25. Outgoing r'ship FOUND_IN to/from Hedychium Coronarium (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730060310
  • 26. Outgoing r'ship FOUND_IN to/from Hierochloe Odorata (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730060108
  • 27. Outgoing r'ship FOUND_IN to/from Humulus Lupulus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Ipomoea Nil (Plant) Rel Props:Reference:ISBN:9788172361150
  • 29. Outgoing r'ship FOUND_IN to/from Lithospermum Erythrorhizon (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 30. Outgoing r'ship FOUND_IN to/from Mangifera Indica (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1812
  • 31. Outgoing r'ship FOUND_IN to/from Morinda Citrifolia (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 32. Outgoing r'ship FOUND_IN to/from Mosla Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Paederia Foetida (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730090106
  • 34. Outgoing r'ship FOUND_IN to/from Pimpinella Anisum (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/12617576
  • 35. Outgoing r'ship FOUND_IN to/from Pogostemon Cablin (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 36. Outgoing r'ship FOUND_IN to/from Polygala Senega (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730100408
  • 37. Outgoing r'ship FOUND_IN to/from Prunus Armeniaca (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 38. Outgoing r'ship FOUND_IN to/from Prunus Persica (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2016.1150218
  • 39. Outgoing r'ship FOUND_IN to/from Punica Granatum (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2035
  • 40. Outgoing r'ship FOUND_IN to/from Schisandra Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 41. Outgoing r'ship FOUND_IN to/from Spondias Dulcis (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730100608
  • 42. Outgoing r'ship FOUND_IN to/from Syzygium Aromaticum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 43. Outgoing r'ship FOUND_IN to/from Tamarindus Indica (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.1998.9700886
  • 44. Outgoing r'ship FOUND_IN to/from Tilia Cordata (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730010204
  • 45. Outgoing r'ship FOUND_IN to/from Vaccinium Corymbosum (Plant) Rel Props:Source_db:fooddb_chem_all;npass_chem_all
  • 46. Outgoing r'ship FOUND_IN to/from Vaccinium Macrocarpon (Plant) Rel Props:Source_db:fooddb_chem_all
  • 47. Outgoing r'ship FOUND_IN to/from Vaccinium Myrtillus (Plant) Rel Props:Source_db:fooddb_chem_all;npass_chem_all
  • 48. Outgoing r'ship FOUND_IN to/from Valeriana Jatamansi (Plant) Rel Props:Reference:ISBN:9788171360536