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3,4,5-Trimethoxytoluene

PubChem CID: 80922

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Compound Synonyms 3,4,5-Trimethoxytoluene, 6443-69-2, 1,2,3-Trimethoxy-5-methylbenzene, Benzene, 1,2,3-trimethoxy-5-methyl-, Toluene, 3,4,5-trimethoxy-, EINECS 229-239-0, MFCD00008397, CHEMBL156710, CHEBI:81354, DTXSID80214683, EC 229-239-0, 5-methyl-1,2,3-trimethoxybenzene, Benzene, 5-methyl-1,2,3-trimethoxy, 5-Methylpyrogallol trimethyl ether, 1,2,3-Trimethoxy-5-methyl-benzene, DZV7MLT5SB, 3,4,5-trimethoxy-toluene, 3,4,5-Trimethoxy toluene, (3,4,5-Trimethoxy)toluene, SCHEMBL171116, DTXCID10137174, 3,4,5-Trimethoxytoluene, 97%, BDBM50008538, AKOS000121615, AC-4356, CS-W017113, FT71325, AS-57893, SY030334, DB-021836, NS00004405, T1236, EN300-16619, C17822, D70896, Q27155292, Z56347223, 229-239-0
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 27.7
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Deep Smiles COccOC))cccc6OC))))C
Heavy Atom Count 13.0
Classyfire Class Phenol ethers
Description 1,2,3-trimethoxy-5-methylbenzene is a member of the class of compounds known as anisoles. Anisoles are organic compounds containing a methoxybenzene or a derivative thereof. 1,2,3-trimethoxy-5-methylbenzene is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 1,2,3-trimethoxy-5-methylbenzene can be found in safflower and tea, which makes 1,2,3-trimethoxy-5-methylbenzene a potential biomarker for the consumption of these food products.
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Anisoles
Isotope Atom Count 0.0
Molecular Complexity 135.0
Database Name cmaup_ingredients;fooddb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22303
Iupac Name 1,2,3-trimethoxy-5-methylbenzene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT204
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C10H14O3
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 1.0
Inchi Key KCIZTNZGSBSSRM-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.4
Logs -2.214
Rotatable Bond Count 3.0
Logd 2.297
Synonyms 1,2,3-Trimethoxy-5-methyl-benzene, 1,2,3-Trimethoxy-5-methylbenzene, 3,4,5-Trimethoxytoluene, 5-Methyl-1,2,3-trimethoxybenzene, 5-Methylpyrogallol trimethyl ether, Benzene, 1,2,3-trimethoxy-5-methyl-, Benzene, 5-methyl-1,2,3-trimethoxy, Methoxyacetylene, Toluene, 3,4,5-trimethoxy-, 1,2,3-trimethoxy-5-methylbenzene, 3,4,5-trimethoxytoluene
Esol Class Soluble
Functional Groups cOC
Compound Name 3,4,5-Trimethoxytoluene
Prediction Hob Swissadme 1.0
Exact Mass 182.094
Formal Charge 0.0
Monoisotopic Mass 182.094
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 182.22
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.2598962615384615
Inchi InChI=1S/C10H14O3/c1-7-5-8(11-2)10(13-4)9(6-7)12-3/h5-6H,1-4H3
Smiles CC1=CC(=C(C(=C1)OC)OC)OC
Nring 1.0
Defined Bond Stereocenter Count 0.0
Egan Rule True

  • 1. Outgoing r'ship FOUND_IN to/from Asarum Heterotropoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Asarum Sieboldii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Carthamus Tinctorius (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Pinellia Ternata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all