Hydroquinone
PubChem CID: 785
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| Compound Synonyms | hydroquinone, 123-31-9, Benzene-1,4-diol, 1,4-benzenediol, Quinol, 1,4-Dihydroxybenzene, p-Benzenediol, p-Hydroquinone, p-Hydroxyphenol, 4-Hydroxyphenol, p-Dihydroxybenzene, Benzoquinol, hydroquinol, Dihydroquinone, Eldoquin, p-Dioxybenzene, Solaquin forte, Eldopaque, Hydroquinole, Idrochinone, Tecquinol, Phiaquin, Benzohydroquinone, Hidroquinone, Arctuvin, Tequinol, Dihydroxybenzene, Eldopaque Forte, Eldoquin Forte, Derma-Blanch, Hydrochinon, Tenox HQ, Diak 5, Benzene, p-dihydroxy-, Hydrochinone, 1,4-Dihydroxy-benzol, Artra, Usaf ek-356, 1,4-Diidrobenzene, p-Dioxobenzene, 1,4-Dihydroxybenzen, para-Dioxybenzene, para-Hydroquinone, NCI-C55834, Black and White Bleaching Cream, 1,4-Dihydroxy-benzeen, para-Dihydroxybenzene, beta-quinol, HE 5, Pyrogentistic acid, Epiquin, Melanex, Sunvanish, Idrochinone [Italian], p-Dihydroquinone, alpha-hydroquinone, CHEBI:17594, NSC 9247, Hydrochinon [Czech, Polish], CCRIS 714, 1,4-Dihydroxybenzen [Czech], 1,4-Diidrobenzene [Italian], HSDB 577, DTXSID7020716, 1,4-Dihydroxy-benzeen [Dutch], 1,4-Dihydroxy-benzol [German], AI3-00072, CHEMBL537, UNII-XV74C1N1AE, NSC-9247, EINECS 204-617-8, XV74C1N1AE, MFCD00002339, UN2662, Hydroquinone (USP), Hydroquinone [USP], HQ, DTXCID70716, NSC9247, EC 204-617-8, Hydroquinone [UN2662] [Poison], 1,4-Dihydroxybenzene (ring-d4), TRI-LUMA COMPONENT HYDROQUINONE, NCGC00015523-02, HYDROQUINONE (IARC), HYDROQUINONE [IARC], para-Hydroxyphenol, Quinol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, HYDROQUINONE (MART.), HYDROQUINONE [MART.], HYDROQUINONE (USP-RS), HYDROQUINONE [USP-RS], quinnone, Eldopacque, p-Phenylenediol, p Benzendiol, HYDROQUINONE (USP MONOGRAPH), HYDROQUINONE [USP MONOGRAPH], p-Quinol, 1,4-Benzoquinol, CAS-123-31-9, SMR000059154, 1,4-Hydroxybenzene, SR-01000075920, BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY), BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY], 4-DIHYDROXYBENZENE, hydroquinon, BQ(H), Hydroquinoue, Balancer, MedisilkeNight, Supermax, hydroq uinone, hydroquinone gr, MiracleFade, Reduced quinone, a-Hydroquinone, Activator Light, Corrector Light, Skin Lightener, Black & White Bleaching Cream, Clear Action, Double White, Exence White, Hydroquinone gel, Idole Carrot, Movate Carrot, Movate Lemon, p-Hydroxybenzene, Scarlight Md, b-Quinol, Caro Light, Hot Movate, Idole Black, 4-Benzenediol, 4-hydroxyphenoxy, Hydroquinone 4%, Hydroquinone cream, Nova Complex HQ, Hydroquinone, HQ, Light The Way, .beta.-Quinol, 1,4 benzenediol, Clarite 4, Hydro-Q, Obagi-C, Seequin 2, Seequin 4, Active 4, Hydroquinone,(S), p-dihydroxy benzene, PLQ, Artra (Salt/Mix), HQLA, HYDROP, I-max Lightening 5, PIONA, .alpha.-Hydroquinone, Skin lightening Cream, African Formula Black, NeovaComplex HQ Plus, phenol derivative, 4, Skin Beautifying Milk, African Formula Carrot, Essential Fade Complex, Clear-N-Smooth PLUS, 4-hydroxyphenyl alcohol, NU-DERM BLENDER, NU-DERM CLEAR, Skin Lightening Complex, Spectrum_001757, SYMBA Skin Lightening, 4e3h, Image Md Lightening Rx, BRIGHTENLIGHTENING, HYDROQUINONE 6%, HYDROQUINONE 8%, SpecPlus_000769, 1,4-Dihydrobenzoquinone, Clear-N-Smooth Ultimate, Clear-N-Smooth SuperMax, Clear-N-Smooth UltraMax, ELDOQUIN (TN), EB5 Age Spot Treatment, Gold Cosmetics Adi Clear, hydroquinone for synthesis, Hydroquinone Time Release, Rejuvaderm Medispa Fading, Spectrum2_001672, Spectrum3_000656, Spectrum4_000633, Spectrum5_001430, HYDROQUINONE [MI], Lopac-H-9003, HYDROQUINONE 8%., WLN: QR DQ, bmse000293, Dark Spot Lightening Cream, Epitope ID:116206, Sh18, HYDROQUINONE [HSDB], Skin LighteningRodan Fields, PLUS Skin lightening Cream, Gold Cosmetics Bleach Cream, Vividly Brilliant Perfecting, HYDROQUINONE [VANDF], 1,4-Dihydroxybenzene Quinol, Lopac0_000577, SCHEMBL15516, BSPBio_002291, KBioGR_001246, KBioSS_002237, 1,4-Dihydroxybenzene, XIII, MLS000069815, MLS001074911, Pure Valley Miracle Age Spot, BIDD:ER0340, DivK1c_006865, HYDROQUINONE [WHO-DD], Hydroquinone, LR, >=99%, SPECTRUM1504237, Clear-N-Smooth Super-Ultimate, Hydrochinon(CZECH, POLISH), SPBio_001883, Precious Beauty Skin Lightening, Body Fade CremeMaximum Strength, PLEXADERM Dark Spot Fade Gel, ULTIMATE Skin lightening Cream, BDBM26190, Hydroquinone, puriss., 99.0%, KBio1_001809, KBio2_002237, KBio2_004805, KBio2_007373, KBio3_001511, MSK2901, Benzene-1,4-diol (Hydroquinone), Gold Cosmetics Bleach Cream Forte, HQ Plus Brightening CreamVI Derm, DTXSID001316808, HMS1922H15, HMS2093E08, HMS3261D16, HYDROQUINONE [ORANGE BOOK], OLIVIA QUIDO BLEMISH ERASER, Pharmakon1600-01504237, Ageless Total Skin Bleaching Serum, DermisaSkin Fade Vitamin C infused, Gold Cosmetics Bleach Cream Silver, Divine Derrier Skin Bleaching cream, Dr. Lightening Ultra-Potent Facial, HY-B0951, Obagi-C Rx system C-Therapy Night, Tox21_110169, Tox21_202345, Tox21_300015, Tox21_500577, 141010 HYDROQUINONE 4%, 141011 HYDROQUINONE 6%, 141030 HYDROQUINONE 8%, 141055 HYDROQUINONE 6%, 141067 HYDROQUINONE 8%, CCG-39082, MD Acne Medicated Dark Spot Remover, NSC758707, Olivia Quido Skincare Blemish Eraser, s4580, STK397446, AKOS000119003, Obagi C Rx System C Clarifying Serum, Teatrical Pro-Aclarant Skin Lightening, Tox21_110169_1, 1ST2901, DB09526, FH01233, LP00577, NSC-758707, RP10102, SDCCGSBI-0050559.P003, UN 2662, Hydroquinone, ReagentPlus(R), >=99%, Hydroquinone, USP, 99.0-100.5%, NCGC00015523-01, NCGC00015523-03, NCGC00015523-04, NCGC00015523-05, NCGC00015523-06, NCGC00015523-07, NCGC00015523-08, NCGC00015523-09, NCGC00015523-10, NCGC00015523-11, NCGC00015523-12, NCGC00015523-13, NCGC00015523-19, NCGC00090880-01, NCGC00090880-02, NCGC00090880-03, NCGC00090880-04, NCGC00090880-05, NCGC00254037-01, NCGC00259894-01, NCGC00261262-01, BP-21160, DA-33570, Dr. Throwers Skin Lightening Moisturizing, HYDROQUINONE COMPONENT OF TRI-LUMA, Hydroquinone, ReagentPlus(R), >=99.5%, SBI-0050559.P002, Hydroquinone, SAJ first grade, >=99.0%, NU-DERM CLEARSkin Bleaching and Corrector, EU-0100577, H0186, Hydroquinone, SAJ special grade, >=99.0%, MEDITOWELILLUMINATING SKIN BRIGHTENING, NS00004421, NU-DERM BLENDERSkin Lightener and Blending, EN300-18053, Hydroquinone, meets USP testing specifications, Advanced Dual Complex FadeMaximum Strength Plus, C00530, D00073, H 9003, AB00053361_08, Q419164, ZO Skin Health Pigment Control Creme Hydroquinone, SR-01000075920-1, SR-01000075920-4, BRD-K11227669-001-07-8, BRD-K11227669-001-08-6, Q27102742, Z57127551, 094CADDB-59BF-4EDF-B278-59791B203EA2, F1908-0167, Hydroquinone, certified reference material, TraceCERT(R), OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oily, ZO Skin Health Pigment Control Program Plus Hydroquinone, CONDITION AND ENHANCE BLENDERSkin Lightener and Blending, CONDITION AND ENHANCE CLEARSkin Bleaching and Corrector, ZO Skin Health Pigment Control Plus Blending Creme Hydroquinone, ELASTIDERM DECOLLETAGE SKIN LIGHTENING COMPLEXChest and Neck, Hydroquinone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8, Obagi-C Rx system C-Therapy NightSkin Lightening with Vitamins C and E, Hydroquinone, Pharmaceutical Secondary Standard, Certified Reference Material, ZO MEDICAL MELAMIN-C Skin Bleaching and Correcting with Vitamin C Hydroquinone, ZO Skin Health Pigment Control plus Brightening Creme Hydroquinone plus Vitamin C, 204-617-8, 3225-30-7, OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oilySKIN LIGHTENING SERUM WITH VITAMIN C |
|---|---|
| Ghose Rule | False |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 40.5 |
| Hydrogen Bond Donor Count | 2.0 |
| Pfizer 3 75 Rule | False |
| Scaffold Graph Level | C1CCCCC1 |
| Deep Smiles | Occcccc6))O |
| Heavy Atom Count | 8.0 |
| Classyfire Class | Phenols |
| Description | Hydroquinone, also benzene-1,4-diol, is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2. Its chemical structure has two hydroxyl groups bonded to a benzene ring in a para position. Hydroquinone is commonly used as a biomarker for benzene exposure. The presence of hydroquinone in normal individuals stems mainly from direct dietary ingestion, catabolism of tyrosine and other substrates by gut bacteria, ingestion of arbutin containing foods, cigarette smoking, and the use of some over-the-counter medicines. Hydroquinone is a white granular solid at room temperature and pressure. The hydroxyl groups of hydroquinone are quite weakly acidic. Hydroquinone can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion. Hydroquinone has a variety of uses principally associated with its action as a reducing agent which is soluble in water. It is a major component in most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver. [HMDB]. Hydroquinone is found in many foods, some of which are kai-lan, agar, red bell pepper, and jostaberry. |
| Scaffold Graph Node Level | C1CCCCC1 |
| Classyfire Subclass | Benzenediols |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 54.9 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 0.0 |
| Enzyme Uniprot Id | Q15166, P27169, Q15165 |
| Uniprot Id | P14679, Q15166, P27169, Q15165, P16083, P22309, P15559, O42713, P00915, P00918, Q99N23, n.a., P35354, Q9D6N1, Q9ULX7, O43570, Q16790, P43166, P23280, Q9Y2D0, P35218, P22748, P07451, Q03164, P02545, P19838, P46063, Q99714, B2RXH2, P51151, P51450, P0A6C1, Q16665, P00352, Q01453, P42345, Q9F4F7, P16050, P10636, P68871, P15917, P54132, O15118, P15428, P40225, P08482, P08684, O75496, Q99549, P13267, P03070, Q96KQ7, O15648, P83916, Q13526, Q96QE3, Q2PCB5, P19793, Q99700, P03372, P10828, Q96RI1, O89049, P39748, P10275, P49798, Q03181, P04150, Q9HAW8, Q9HAW7, P25094, P35869, Q16236, O94925, P10145, P51449, Q9NUW8, Q9NPD5, Q9Y6L6, P15289, O42275, P0DTD1, P04792, P05412 |
| Iupac Name | benzene-1,4-diol |
| Prediction Hob | 1.0 |
| Class | Benzene and substituted derivatives |
| Veber Rule | True |
| Classyfire Superclass | Benzenoids |
| Target Id | NPT947, NPT233, NPT954, NPT949, NPT948, NPT955, NPT1063, NPT1144, NPT1143, NPT1062, NPT1146, NPT483, NPT163, NPT47, NPT149, NPT48, NPT537, NPT211, NPT94, NPT796, NPT940, NPT792, NPT51, NPT2930, NPT58, NPT538, NPT151, NPT96, NPT109, NPT10, NPT741 |
| Xlogp | 0.6 |
| Superclass | Benzenoids |
| Subclass | Phenols and derivatives |
| Gsk 4 400 Rule | True |
| Molecular Formula | C6H6O2 |
| Scaffold Graph Node Bond Level | c1ccccc1 |
| Prediction Swissadme | 0.0 |
| Inchi Key | QIGBRXMKCJKVMJ-UHFFFAOYSA-N |
| Silicos It Class | Soluble |
| Fcsp3 | 0.0 |
| Logs | -0.011 |
| Rotatable Bond Count | 0.0 |
| State | Solid |
| Logd | 0.89 |
| Synonyms | 1,4-Benzenediol, 1,4-Dihydroxy-benzeen, 1,4-Dihydroxy-benzol, 1,4-Dihydroxybenzen, 1,4-Dihydroxybenzene, 1,4-Diidrobenzene, 4-Hydroxyphenol, a-Hydroquinone, alpha-Hydroquinone, Arctuvin, b-Quinol, Benzene-1,4-diol, Benzohydroquinone, Benzoquinol, beta-Quinol, Dihydroquinone, Dihydroxybenzene, Eldopaque, Eldoquin, Hydrochinon, Hydrochinone, Hydroquinol, Hydroquinole, Hydroquinone for synthesis, Hydroquinone gr, Hydroquinone, 8CI, USAN, Hydroquinoue, Idrochinone, Melanex, P-Benzenediol, P-Dihydroxybenzene, P-Dioxobenzene, P-Dioxybenzene, P-Hydroquinone, P-Hydroxybenzene, P-Hydroxyphenol, Phiaquin, Pyrogentisic acid, Pyrogentisinic acid, Quinol, Solaquin forte, p-Benzenediol, p-Hydroquinone, p-Hydroxyphenol, Artra, Esoterica, Hidroquilaude, Hidroquin, Hidroquinona isdin, Licostrata, Lustra, Melanasa, Melpaque, Melquin, Neostrata HQ, Solaquin, Ultraquin, Hydroquinone, copper (1+) salt, Hydroquinone, lead (2+) salt (2:1), Hydroquinone, monocopper (2+) salt, Hydroquinone GR, p-Dihydroxybenzene, p-Dioxybenzene, Eldoquin forte, Stratus brand 1 OF hydroquinone, ICN brand 1 OF hydroquinone, Plough brand 2 OF hydroquinone, Eldopaque forte, ICN brand 4 OF hydroquinone, Black and white, ICN brand 2 OF hydroquinone, ICN brand 3 OF hydroquinone, Plough brand 1 OF hydroquinone, Stratus brand 2 OF hydroquinone, 1,4-Benzoquinol, 1,4-Phenylenediol, 1,4-p-Benzenediol, p-Dihydroquinone, p-Phenylenediol, p-Quinol, 1,4-benzenediol, hydroquinone |
| Substituent Name | Hydroquinone, Hydrocarbon derivative, Organooxygen compound, Aromatic homomonocyclic compound |
| Esol Class | Very soluble |
| Functional Groups | cO |
| Compound Name | Hydroquinone |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 0.0 |
| Exact Mass | 110.037 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 110.037 |
| Hydrogen Bond Acceptor Count | 2.0 |
| Molecular Weight | 110.11 |
| Gi Absorption | True |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 0.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Lipinski Rule Of 5 | True |
| Esol | -1.4493943999999996 |
| Inchi | InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H |
| Smiles | C1=CC(=CC=C1O)O |
| Nring | 1.0 |
| Np Classifier Biosynthetic Pathway | Shikimates and Phenylpropanoids |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | True |
| Taxonomy Direct Parent | Hydroquinones |
- 1. Outgoing r'ship
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FOUND_INto/from Ocimum Tenuiflorum (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2014.931255 - 53. Outgoing r'ship
FOUND_INto/from Origanum Majorana (Plant) Rel Props:Source_db:fooddb_chem_all - 54. Outgoing r'ship
FOUND_INto/from Pimpinella Anisum (Plant) Rel Props:Source_db:fooddb_chem_all - 55. Outgoing r'ship
FOUND_INto/from Pinus Resinosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 56. Outgoing r'ship
FOUND_INto/from Pleione Bulbocodioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 57. Outgoing r'ship
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FOUND_INto/from Pyrus Communis (Plant) Rel Props:Source_db:fooddb_chem_all - 59. Outgoing r'ship
FOUND_INto/from Pyrus Pashia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 60. Outgoing r'ship
FOUND_INto/from Quercus Sessiliflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 61. Outgoing r'ship
FOUND_INto/from Rhododendron Dauricum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 62. Outgoing r'ship
FOUND_INto/from Rubus Plicatus (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279 - 63. Outgoing r'ship
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FOUND_INto/from Satureja Atropatana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 65. Outgoing r'ship
FOUND_INto/from Saussurea Carthamoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 66. Outgoing r'ship
FOUND_INto/from Saxifraga Stolonifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 67. Outgoing r'ship
FOUND_INto/from Scutellaria Barbata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 68. Outgoing r'ship
FOUND_INto/from Senecio Scandens (Plant) Rel Props:Reference:ISBN:9788185042114 - 69. Outgoing r'ship
FOUND_INto/from Solanum Acaule (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 70. Outgoing r'ship
FOUND_INto/from Sparganium Erectum (Plant) Rel Props:Reference:ISBN:9788185042138 - 71. Outgoing r'ship
FOUND_INto/from Swertia Delavayi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 72. Outgoing r'ship
FOUND_INto/from Tinospora Sinensis (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2013.831568 - 73. Outgoing r'ship
FOUND_INto/from Vaccinium Myrtillus (Plant) Rel Props:Source_db:fooddb_chem_all - 74. Outgoing r'ship
FOUND_INto/from Viburnum Opulus (Plant) Rel Props:Reference:ISBN:9780387706375 - 75. Outgoing r'ship
FOUND_INto/from Vismia Jefensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 76. Outgoing r'ship
FOUND_INto/from Zanthoxylum Acanthopodium (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2008.9700075