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Vindolinine. 19-epimer, N-oxide

PubChem CID: 78358538

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Compound Synonyms Vindolinine. 19-epimer, N-oxide, 16-epi-19-S-Vindolinine-N-oxide, 88720-99-4
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 56.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC13CCC4(CCCC5CCC21C54)C3
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)[C@H]C[C@@][C@H][C@@]5Ncc[C@]5[C@H]8[N+]CC5))CC=C%12)))[O-]))))cccc6))))))))C
Heavy Atom Count 26.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level C1CCC2C(C1)NC13CCC4(CCCN5CCC21C54)C3
Classyfire Subclass Carbazoles
Isotope Atom Count 0.0
Molecular Complexity 724.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1R,9R,10S,12R,19S,20R)-20-methyl-16-oxido-8-aza-16-azoniahexacyclo[10.6.1.19,12.01,9.02,7.016,19]icosa-2,4,6,13-tetraene-10-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.4
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level C1=CC23CCC4(C2)Nc2ccccc2C42CC[NH+](C1)C32
Prediction Swissadme 1.0
Inchi Key JOAAIYRFWUHKSF-IVTYPWQJSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5714285714285714
Logs -2.158
Rotatable Bond Count 2.0
Logd 0.644
Synonyms 16-epi-19-s-vindolinine-n-oxide, 16-epi-19s-vindolinine n-oxide, vindolinine-nb-oxide
Esol Class Soluble
Functional Groups CC=CC, COC(C)=O, C[N+](C)(C)[O-], cNC
Compound Name Vindolinine. 19-epimer, N-oxide
Prediction Hob Swissadme 1.0
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.5506600307692313
Inchi InChI=1S/C21H24N2O3/c1-13-19-8-5-10-23(25)11-9-20(18(19)23)14-6-3-4-7-16(14)22-21(13,20)15(12-19)17(24)26-2/h3-8,13,15,18,22H,9-12H2,1-2H3/t13-,15-,18+,19+,20-,21-,23?/m1/s1
Smiles C[C@@H]1[C@]23C[C@@H]([C@@]14[C@@]5([C@H]2[N+](CC5)(CC=C3)[O-])C6=CC=CC=C6N4)C(=O)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all