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4-Methoxyphenylacetic Acid

PubChem CID: 7690

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Compound Synonyms 4-Methoxyphenylacetic acid, 104-01-8, 2-(4-methoxyphenyl)acetic acid, Homoanisic acid, p-Methoxyphenylacetic acid, Benzeneacetic acid, 4-methoxy-, (4-Methoxyphenyl)acetic acid, 4-Methoxybenzeneacetic acid, 2-(p-Anisyl)acetic acid, (p-Methoxyphenyl)acetic acid, p-Anisylacetic acid, p-Methoxy-alpha-toluic acid, MFCD00004345, NSC 27799, Homoanisate, 4-Methoxyphenylaceticacid, CHEBI:55501, Acetic acid, (p-methoxyphenyl)-, EINECS 203-166-4, AJP2V8U5K6, Homo-p-anisic acid, Acetic acid, p-methoxyphenyl-, p-Methoxy-a-toluate, BRN 1101737, (4-Methoxy-phenyl)-acetic acid, 2-(p-Anisyl)acetate, 4-Methoxybenzeneacetate, p-methoxyphenyl-acetate, p-Methoxy-alpha-toluate, 4-methoxy-benzeneacetate, 4-methoxyphenacetic acid, p-Methoxy-a-toluic acid, (p-Methoxyphenyl)acetate, NSC-27799, NSC-65597, p-methoxyphenyl-acetic acid, UNII-AJP2V8U5K6, 4-Methoxy phenylacetic acid, 4-methoxyphenylacetate, (4-Methoxy-phenyl)-acetate, 4-methoxy-benzeneacetic acid, p-Methoxy-.alpha.-toluic acid, DTXSID1059288, 4-10-00-00544 (Beilstein Handbook Reference), 2-(P-METHOXYPHENYL)ACETIC ACID, WLN: QV1R DO1, 4-Methoxyphenyl acetic acid, p-Methoxyphenylacetate, ONONETIN_met012, p-Methoxy-I+--toluate, (4-methoxyphenyl)acetate, Epitope ID:119696, p-methoxyphenyl acetic acid, p-Methoxy-I+--toluic acid, para-methoxyphenylacetic acid, NCIOpen2_000187, p-methoxy phenyl acetic acid, SCHEMBL240822, (4-methoxyphenyl)-acetic acid, (4methoxy-phenyl)-acetic acid, (4-methoxyphenyl)ethanoic acid, CHEMBL1760597, DTXCID3032836, 2-(4-methoxyphenyl)-acetic acid, [4-(methyloxy)phenyl]acetic acid, BDBM231634, BCP27492, NSC27799, NSC65597, STR06306, acetic acid, 2-(4-methoxyphenyl)-, BBL009361, s6273, STK498739, AKOS000119748, AC-2432, CS-W004206, FM71195, HY-W004206, PS-3381, PD124018, SY001095, M0742, NS00023274, EN300-19915, D70488, M13960, 4-Methoxyphenylacetic acid, ReagentPlus(R), 99%, AE-562/40223956, Q63398108, F3308-1732, Z104476074, 4-Methoxyphenylacetic acid, Vetec(TM) reagent grade, 98%, 203-166-4
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Np Classifier Class Simple phenolic acids
Deep Smiles COcccccc6))CC=O)O
Heavy Atom Count 12.0
Classyfire Class Phenol ethers
Description 4-Methoxyphenylacetic acid is a 4-O-Methylated catecholamine metabolite found in normal human urine, cerebrospinal fluid and brain tissue. (PMIDs 6511847, 4645252, 12416886) [HMDB]
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Anisoles
Isotope Atom Count 0.0
Molecular Complexity 148.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P59534
Iupac Name 2-(4-methoxyphenyl)acetic acid
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 1.4
Superclass Benzenoids
Subclass Phenylacetic acid derivatives
Gsk 4 400 Rule True
Molecular Formula C9H10O3
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key NRPFNQUDKRYCNX-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.2222222222222222
Logs -1.559
Rotatable Bond Count 3.0
State Solid
Logd 2.736
Synonyms (4-Methoxy-phenyl)-acetate, (4-Methoxy-phenyl)-acetic acid, (4-Methoxyphenyl)acetate, (4-Methoxyphenyl)acetic acid, (p-Methoxyphenyl)acetate, (p-Methoxyphenyl)acetic acid, 2-(p-Anisyl)acetate, 2-(p-Anisyl)acetic acid, 4-Methoxy phenylacetic acid, 4-methoxy-benzeneacetate, 4-methoxy-benzeneacetic acid, 4-Methoxybenzeneacetate, 4-Methoxybenzeneacetic acid, 4-Methoxyphenylacetate, Homo-p-anisic acid, Homoanisate, Homoanisic acid, p-Methoxy-a-toluate, p-Methoxy-a-toluic acid, p-Methoxy-alpha-toluate, p-Methoxy-alpha-toluic acid, P-Methoxy-α-toluate, P-Methoxy-α-toluic acid, p-methoxyphenyl-acetate, p-methoxyphenyl-acetic acid, P-Methoxyphenylacetate, P-Methoxyphenylacetic acid, p-Methoxyphenylacetic acid, p-Methoxy-α-toluate, p-Methoxy-α-toluic acid, p-Methoxyphenylacetate, 3-Methoxyphenylacetic acid, potassium salt, 3-Methoxyphenylacetic acid, 4-Methoxy-benzeneacetate, 4-Methoxy-benzeneacetic acid, homo-P-Anisic acid, P-Methoxyphenyl-acetate, P-Methoxyphenyl-acetic acid, 4-methoxyphenylacetic acid
Substituent Name Phenylacetate, Methoxybenzene, Phenol ether, Anisole, Alkyl aryl ether, Monocarboxylic acid or derivatives, Ether, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aromatic homomonocyclic compound
Esol Class Very soluble
Functional Groups CC(=O)O, cOC
Compound Name 4-Methoxyphenylacetic Acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 166.063
Formal Charge 0.0
Monoisotopic Mass 166.063
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 166.17
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -1.9368911999999998
Inchi InChI=1S/C9H10O3/c1-12-8-4-2-7(3-5-8)6-9(10)11/h2-5H,6H2,1H3,(H,10,11)
Smiles COC1=CC=C(C=C1)CC(=O)O
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Anisoles
Np Classifier Superclass Phenolic acids (C6-C1)

  • 1. Outgoing r'ship FOUND_IN to/from Berberis Koreana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Plumeria Rubra (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730090612