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N-Methylaniline

PubChem CID: 7515

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Compound Synonyms N-METHYLANILINE, 100-61-8, Methylaniline, Benzenamine, N-methyl-, N-Methyl aniline, Monomethylaniline, Methylphenylamine, N-Methylbenzenamine, N-Monomethylaniline, Aniline, N-methyl-, N-Phenylmethylamine, (Methylamino)benzene, N-Methylaminobenzene, Anilinomethane, N-Methylphenylamine, Monomethyl aniline, Benzeneamine, N-methyl-, methyl-phenyl-amine, NSC 3502, CCRIS 2870, N-Methyl-N-phenylamine, HSDB 1654, EINECS 202-870-9, UNII-TH45GK410O, UN2294, DTXSID9021841, CHEBI:15733, AI3-19498, ANILINE,N-METHYL, NSC-3502, METHYLANILINE [MI], DTXCID301841, TH45GK410O, EC 202-870-9, UN 2294, (methylamino) benzene, MFCD00008283, Methylanilines, N-metylaniline, N-Methlaniline, N-methyl-aniline, NMethylbenzenamine, NMethylphenylamine, NMonomethylaniline, NPhenylmethylamine, Aniline, Nmethyl, NMethylaminobenzene, methyl(phenyl)amine, methyl-phenyl amine, n-methylphenyl amine, N-methyl phenylamine, N-methyl-benzenamine, Benzeneamine, Nmethyl, N-Methylanilinium ion, N-methyl-phenyl-amine, n-phenyl-n-methylamine, N-Methylaniline, 98%, N-Methylaniline (ACGIH), N-Methyl-N-phenylamine #, Monomethyl aniline (OSHA), N-Methylaniline, >=99%, SCHEMBL4454, WLN: 1MR, METHYLANILINE (MONO), MLS002415757, BIDD:ER0250, BIDD:GT0230, Benzenamine, N-methyl-(9CI), CHEMBL170781, SCHEMBL1415355, CHEBI:25275, NSC3502, HMS3039I05, N-Methylaniline, analytical standard, Tox21_200298, STL183283, AKOS000119086, BENZENEAMINE,N-METHYL-(9 CI), FM37894, RP10006, N-Methylaniline [UN2294] [Poison], NCGC00091265-01, NCGC00091265-02, NCGC00257852-01, AS-12865, BP-31133, CAS-100-61-8, SMR001370917, N-Methylaniline, purum, >=98.0% (GC), M0147, NS00010869, EN300-19055, C02299, Q1959597, F2190-0405, Z104472478, 1MR
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 12.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Np Classifier Class Aminoacids
Deep Smiles CNcccccc6
Heavy Atom Count 8.0
Classyfire Class Organonitrogen compounds
Description N-methylaniline, also known as methylphenylamine or N-methylbenzenamine, is a member of the class of compounds known as phenylalkylamines. Phenylalkylamines are organic amines where the amine group is secondary and linked on one end to a phenyl group and on the other end, to an alkyl group. N-methylaniline is soluble (in water) and a strong basic compound (based on its pKa). N-methylaniline can be found in a number of food items such as carrot, wild carrot, orange bell pepper, and red bell pepper, which makes N-methylaniline a potential biomarker for the consumption of these food products. N-Methylaniline (NMA) is an aniline derivative. It is an organic compound with the chemical formula C6H5NH(CH3). The substance exists as a colorless or slightly yellow viscous liquid and turns brown when exposed to air. The chemical is insoluble in water. It is used as a latent and coupling solvent and is also used as an intermediate for dyes, agrochemicals and other organic products manufacturing. NMA is toxic and exposure can cause damage to the central nervous system and can also cause liver and kidney failure .
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Amines
Isotope Atom Count 0.0
Molecular Complexity 55.4
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P16473, O94782, O95398
Iupac Name N-methylaniline
Prediction Hob 1.0
Class Organonitrogen compounds
Veber Rule True
Classyfire Superclass Organic nitrogen compounds
Target Id NPT210
Xlogp 1.7
Superclass Organic nitrogen compounds
Subclass Amines
Gsk 4 400 Rule True
Molecular Formula C7H9N
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key AFBPFSWMIHJQDM-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.1428571428571428
Logs -1.483
Rotatable Bond Count 1.0
State liquid
Logd 1.817
Synonyms (methylamino)benzene, Aniline, n-methyl-, Aniline,n-methyl, Anilinomethane, Benzenamine, n-methyl-, Benzeneamine, n-methyl-, Benzenenamine, n-methyl-, MA, Methylaniline, Methylphenylamine, Monomethyl aniline, Monomethylaniline, N-methlaniline, N-methyl aniline, N-methyl-n-phenylamine, N-methylaminobenzene, N-methylaniline, N-Methylaniline [UN2294] [Poison], N-methylanilinium ion, N-methylbenzenamine, N-methylphenylamine, N-monomethylaniline, N-phenylmethylamine, (Methylamino)benzene, N-Methyl-N-phenylamine, N-Methylaminobenzene, N-Methylbenzenamine, N-Methylphenylamine, N-Monomethylaniline, N-Phenylmethylamine, Methylaniline hydrochloride, n-methylaniline
Esol Class Soluble
Functional Groups cNC
Compound Name N-Methylaniline
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 107.073
Formal Charge 0.0
Monoisotopic Mass 107.073
Hydrogen Bond Acceptor Count 1.0
Molecular Weight 107.15
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -2.0391671999999996
Inchi InChI=1S/C7H9N/c1-8-7-5-3-2-4-6-7/h2-6,8H,1H3
Smiles CNC1=CC=CC=C1
Nring 1.0
Np Classifier Biosynthetic Pathway Alkaloids, Amino acids and Peptides, Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Phenylalkylamines
Np Classifier Superclass Small peptides

  • 1. Outgoing r'ship FOUND_IN to/from Apium Graveolens (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Brassica Oleracea (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Capsicum Annuum (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Citrus Reticulata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Citrus Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Citrus Unshiu (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Daucus Carota (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Spinacia Oleracea (Plant) Rel Props:Source_db:fooddb_chem_all