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3-Hydroxybenzoic acid

PubChem CID: 7420

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Compound Synonyms 3-Hydroxybenzoic acid, 99-06-9, M-HYDROXYBENZOIC ACID, m-Salicylic acid, 3-Carboxyphenol, Benzoic acid, 3-hydroxy-, Benzoic acid, m-hydroxy-, m-Hba, Acido m-idrossibenzoico, 3-Hydroxy benzoic acid, Kyselina 3-hydroxybenzoova, NSC 55746, 3-hydroxy-benzoic acid, m-carboxyphenol, meta-Hydroxybenzoic acid, m-hydroxybenzoate, UNII-2ZFW40OJ7U, EINECS 202-726-5, 2ZFW40OJ7U, MFCD00002506, BRN 0508160, DTXSID6021610, CHEBI:30764, AI3-03110, NSC-55746, AC PE 3HB, CHEMBL65369, DTXCID601610, 3HB, Acido m-idrossibenzoico [Italian], Kyselina 3-hydroxybenzoova [Czech], m-salicylate, 3pcb, 3-hydroxy benzoate, meta-hydroxybenzoate, 3-Hydroxybenzoicacid, 3-hydroxybenzoic-acid, metahydroxybenzoic acid, 3-Hydroxybenzoate, II, Enamine_005356, bmse000324, SCHEMBL40078, HMS1409D10, NSC55746, Tox21_200527, BBL011983, BDBM50336491, s6367, STL163473, AKOS000118958, CS-W004049, FH37275, HY-W004049, PS-5406, CAS-99-06-9, NCGC00248676-01, NCGC00258081-01, PD144440, 3-Hydroxybenzoic acid, analytical standard, DB-028515, H0205, NS00014563, 3-Hydroxybenzoic acid, ReagentPlus(R), 99%, EN300-17318, C00587, H60032, AE-562/40227537, doi:10.14272/IJFXRHURBJZNAO-UHFFFAOYSA-N.1, Q2823216, 3-Hydroxybenzoic acid, Vetec(TM) reagent grade, 98%, Z56919254, F9995-1635, 713EC407-4844-477D-8207-DBD66E398D2C, InChI=1/C7H6O3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8H,(H,9,10, 202-726-5, 25302-76-5
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 57.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Np Classifier Class Simple phenolic acids
Deep Smiles Occcccc6)C=O)O
Heavy Atom Count 10.0
Classyfire Class Benzene and substituted derivatives
Description Present in fruits. Isolated from Citrus paradisi (grapefruit) Produced in the gut microflora as one of the three main metabolites formed from the catechin diet. Its use in the production of glycol benzoates for the application of plasticizer in adhesive formulations is increasing. It is also used in the manufacture of alkyd resins and drilling mud additive for crude oil recovery applications. It is used as a rubber polymerization activators and retardants. 3-Hydroxybenzoic acid is found in many foods, some of which are corn, bilberry, citrus, and beer.
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Benzoic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 133.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22309, Q6IB77, P0DMM9, Q9UQ49, P00915, P00918, Q16790, O43570, P23280, Q2PCB5, P18031, Q9BXC0, Q8TDS4, P11473, P48281
Iupac Name 3-hydroxybenzoic acid
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT947, NPT233, NPT948, NPT949, NPT1063, NPT4161, NPT525
Xlogp 1.5
Superclass Benzenoids
Subclass Benzoic acids and derivatives
Gsk 4 400 Rule True
Molecular Formula C7H6O3
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key IJFXRHURBJZNAO-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.0
Logs -1.201
Rotatable Bond Count 1.0
State Solid
Logd 1.424
Synonyms 3-Carboxyphenol, 3-hydroxy benzoate, 3-hydroxy benzoic acid, 3-Hydroxybenzoate, 3pcb, 7720-19-6 (mono-hydrochloride salt), Acido m-idrossibenzoico, Benzoic acid, 3-hydroxy-, Benzoic acid, m-hydroxy-, BEZ, Kyselina 3-hydroxybenzoova, M-hba, M-hydroxybenzoate, M-hydroxybenzoic acid, M-salicylate, M-salicylic acid, Meta-hydroxybenzoate, Meta-hydroxybenzoic acid, m-Hydroxybenzoic acid, m-Salicylic acid, m-Hydroxybenzoate, m-Salicylate, 3-Hydroxybenzoic acid, monosodium salt, Sodium 3-hydroxybenzoic acid, 3-Hydroxybenzoic acid, copper (2+) (1:1) salt, 3-Hydroxy benzoate, 3-Hydroxy benzoic acid, m-Hba, 3-Hydroxybenzoic acid, 3-Hydroxybenzenecarboxylic acid, 3-hydroxybenzoic acid, m-hydroxybenzoic acid
Substituent Name Hydroxybenzoic acid, Benzoic acid, Benzyl alcohol, Benzoyl, Phenol, Monocarboxylic acid or derivatives, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Aromatic alcohol, Organooxygen compound, Carbonyl group, Aromatic homomonocyclic compound
Esol Class Soluble
Functional Groups cC(=O)O, cO
Compound Name 3-Hydroxybenzoic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 138.032
Formal Charge 0.0
Monoisotopic Mass 138.032
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 138.12
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -2.0193564
Inchi InChI=1S/C7H6O3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8H,(H,9,10)
Smiles C1=CC(=CC(=C1)O)C(=O)O
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Hydroxybenzoic acid derivatives
Np Classifier Superclass Phenolic acids (C6-C1)

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  • 2. Outgoing r'ship FOUND_IN to/from Hydrangea Macrophylla (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 3. Outgoing r'ship FOUND_IN to/from Pleione Bulbocodioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Styrax Benzoin (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Styrax Tonkinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Taxus Baccata (Plant) Rel Props:Reference:ISBN:9788172363093
  • 7. Outgoing r'ship FOUND_IN to/from Thymus Quinquecostatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Thymus Vulgaris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Tragopogon Orientalis (Plant) Rel Props:Reference:ISBN:9788185042138
  • 10. Outgoing r'ship FOUND_IN to/from Vaccinium Macrocarpon (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Vaccinium Myrtillus (Plant) Rel Props:Source_db:fooddb_chem_all