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Lappaol F

PubChem CID: 73425459

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Compound Synonyms Lappaol F, 69394-17-8, UNII-5CE539C44W, 5CE539C44W, 2(3H)-Furanone, 3,4-bis(((2S,3R)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl)methyl)dihydro-, (3R,4R)-, 2(3H)-Furanone, 3,4-bis[[(2S,3R)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl]methyl]dihydro-, (3R,4R)-, (3R,4R)-3,4-bis[[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]methyl]oxolan-2-one, DTXSID201318593, HY-N7223, AKOS040761967, DA-74887, CS-0105891, Q27261829
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 163.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC(CC2CCC3CC(C4CCCCC4)CC3C2)C1CC1CCC2CC(C3CCCCC3)CC2C1
Np Classifier Class Dibenzylbutyrolactone lignans, Neolignans
Deep Smiles OC[C@H]cccC[C@H]C=O)OC[C@@H]5CcccOC))ccc6)[C@H]CO))[C@H]O5)cccccc6)OC)))O)))))))))))))))))))ccc6O[C@@H]9cccccc6)OC)))O))))))))OC
Heavy Atom Count 52.0
Classyfire Class 2-arylbenzofuran flavonoids
Description Lappaol f is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Lappaol f is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Lappaol f can be found in burdock, which makes lappaol f a potential biomarker for the consumption of this food product.
Scaffold Graph Node Level OC1OCC(CC2CCC3OC(C4CCCCC4)CC3C2)C1CC1CCC2OC(C3CCCCC3)CC2C1
Isotope Atom Count 0.0
Molecular Complexity 1170.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (3R,4R)-3,4-bis[[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]methyl]oxolan-2-one
Prediction Hob 0.0
Class 2-arylbenzofuran flavonoids
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.5
Superclass Phenylpropanoids and polyketides
Gsk 4 400 Rule False
Molecular Formula C40H42O12
Scaffold Graph Node Bond Level O=C1OCC(Cc2ccc3c(c2)CC(c2ccccc2)O3)C1Cc1ccc2c(c1)CC(c1ccccc1)O2
Prediction Swissadme 0.0
Inchi Key YXNKOCZXAVTXTG-NYGVLQSXSA-N
Silicos It Class Poorly soluble
Fcsp3 0.375
Rotatable Bond Count 12.0
Synonyms (+)-Lappaol F, lappaol f
Esol Class Poorly soluble
Functional Groups CO, COC(C)=O, cO, cOC
Compound Name Lappaol F
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 714.268
Formal Charge 0.0
Monoisotopic Mass 714.268
Hydrogen Bond Acceptor Count 12.0
Molecular Weight 714.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 False
Esol -6.649775261538463
Inchi InChI=1S/C40H42O12/c1-46-32-15-22(5-7-30(32)43)36-28(17-41)26-11-20(13-34(48-3)38(26)51-36)9-24-19-50-40(45)25(24)10-21-12-27-29(18-42)37(52-39(27)35(14-21)49-4)23-6-8-31(44)33(16-23)47-2/h5-8,11-16,24-25,28-29,36-37,41-44H,9-10,17-19H2,1-4H3/t24-,25+,28-,29-,36+,37+/m0/s1
Smiles COC1=CC(=CC2=C1O[C@@H]([C@H]2CO)C3=CC(=C(C=C3)O)OC)C[C@H]4COC(=O)[C@@H]4CC5=CC6=C(C(=C5)OC)O[C@@H]([C@H]6CO)C7=CC(=C(C=C7)O)OC
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent 2-arylbenzofuran flavonoids
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Arctium Lappa (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all