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alpha-Lapachone

PubChem CID: 72732

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Compound Synonyms alpha-Lapachone, 4707-33-9, 2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione, .alpha.-Lapachone, 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4-dihydro-2,2-dimethyl-, VPE3AOX9QV, NSC26327, 2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione, NSC629747, NSC-26327, NSC-629747, 2,2-dimethyl-2H,3H,4H,5H,10H-naphtho[2,3-b]pyran-5,10-dione, Lapachoone alpha, NSC 26327, NSC 629747, 2H-Naphtho(2,3-b)pyran-5,10-dione, 3,4-dihydro-2,2-dimethyl-, UNII-VPE3AOX9QV, Alpha lapachone, alpha-Lapachone?, NSC 26327, NSC 629747, LAPACHONE, ALPHA, LAPACHONE, .alpha., SCHEMBL102553, CHEMBL441441, BDBM24810, DTXSID00197020, CHEBI:182892, PJWHOPKRRBUSDH-UHFFFAOYSA-N, GLXC-17776, EAA70733, HY-N2848, Pyranonaphthoquinone derivative, 51, AKOS028108462, CCG-231496, AC-37066, DA-60950, MS-23427, CS-0023426, NS00015823, E76367, 2H-Naphtho[2,10-dione, 3,4-dihydro-2,2-dimethyl-, Q27291952, 2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione #, 3,4-dihydro-2,2-dimethyl-2H-naphtho[2,3-b]pyran-5,10-dione
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 43.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2C(C)C2CCCCC12
Np Classifier Class Naphthoquinones
Deep Smiles O=CC=CCCCO6)C)C))))C=O)cc6cccc6
Heavy Atom Count 18.0
Classyfire Class Naphthopyrans
Scaffold Graph Node Level OC1C2CCCCC2C(O)C2OCCCC12
Classyfire Subclass Naphthopyranones
Isotope Atom Count 0.0
Molecular Complexity 445.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P14902, n.a., P15559, P16435, G4VFD7
Iupac Name 2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT1078
Xlogp 2.6
Gsk 4 400 Rule True
Molecular Formula C15H14O3
Scaffold Graph Node Bond Level O=C1C2=C(OCCC2)C(=O)c2ccccc21
Prediction Swissadme 0.0
Inchi Key PJWHOPKRRBUSDH-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3333333333333333
Logs -3.548
Rotatable Bond Count 0.0
Logd 3.361
Synonyms alpha-lapachone
Esol Class Soluble
Functional Groups COC1=C(C)C(=O)ccC1=O
Compound Name alpha-Lapachone
Prediction Hob Swissadme 0.0
Exact Mass 242.094
Formal Charge 0.0
Monoisotopic Mass 242.094
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 242.27
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.2582654666666664
Inchi InChI=1S/C15H14O3/c1-15(2)8-7-11-12(16)9-5-3-4-6-10(9)13(17)14(11)18-15/h3-6H,7-8H2,1-2H3
Smiles CC1(CCC2=C(O1)C(=O)C3=CC=CC=C3C2=O)C
Nring 3.0
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Naphthalenes

  • 1. Outgoing r'ship FOUND_IN to/from Catalpa Ovata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Fernandoa Adenophylla (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042114
  • 3. Outgoing r'ship FOUND_IN to/from Handroanthus Serratifolius (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042138
  • 4. Outgoing r'ship FOUND_IN to/from Tabebuia Avellanedae (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Tabebuia Heterophylla (Plant) Rel Props:Reference:ISBN:9788185042114
  • 6. Outgoing r'ship FOUND_IN to/from Tectona Grandis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all