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(2R,7S,10R,11S,13S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-ene-7,13-diol

PubChem CID: 72627

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Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 43.7
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C2CC2C3CCC4CCCCC4C3CCC12
Np Classifier Class Steroidal alkaloids
Deep Smiles O[C@H]CC[C@]C=CC[C@@H][C@@H]6C[C@H]O)[C@]C6C[C@H][C@@H]5[C@H]C)[C@@H]N5C[C@H]CC6))C))))))))))C))))))))C6))C
Heavy Atom Count 30.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level C1CCC2C(C1)CCC1C2CCC2C1CC1C2CC2CCCCN21
Classyfire Subclass Steroidal alkaloids
Isotope Atom Count 0.0
Molecular Complexity 749.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 11.0
Iupac Name (2R,7S,10R,11S,13S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-ene-7,13-diol
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 4.7
Gsk 4 400 Rule False
Molecular Formula C27H43NO2
Scaffold Graph Node Bond Level C1=C2CCCCC2C2CCC3C(CC4C3CC3CCCCN34)C2C1
Prediction Swissadme 0.0
Inchi Key AANKDJLVHZQCFG-LJTVCTDBSA-N
Silicos It Class Soluble
Fcsp3 0.925925925925926
Rotatable Bond Count 0.0
Synonyms rubijervine
Esol Class Moderately soluble
Functional Groups CC=C(C)C, CN(C)C, CO
Compound Name (2R,7S,10R,11S,13S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracos-4-ene-7,13-diol
Prediction Hob Swissadme 0.0
Exact Mass 413.329
Formal Charge 0.0
Monoisotopic Mass 413.329
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 413.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 12.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.390805200000001
Inchi InChI=1S/C27H43NO2/c1-15-5-8-22-16(2)25-23(28(22)14-15)12-21-19-7-6-17-11-18(29)9-10-26(17,3)20(19)13-24(30)27(21,25)4/h6,15-16,18-25,29-30H,5,7-14H2,1-4H3/t15-,16+,18-,19+,20-,21?,22+,23-,24-,25-,26-,27+/m0/s1
Smiles C[C@H]1CC[C@@H]2[C@H]([C@H]3[C@@H](N2C1)CC4[C@@]3([C@H](C[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)O)C)C
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Veratrum Nigrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Veratrum Viride (Plant) Rel Props:Reference:ISBN:9788172362140