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Preakuammicine

PubChem CID: 71768191

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Compound Synonyms Preakuammicine, methyl (1R,10S,11S,12E,17S)-12-ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo(9.5.2.01,9.02,7.014,17)octadeca-2,4,6,8-tetraene-10-carboxylate, methyl (1R,10S,11S,12E,17S)-12-ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraene-10-carboxylate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34C(CC1CC23)CC1CCCCC14
Np Classifier Class Aspidosperma type, Corynanthe type
Deep Smiles C/C=C/CNCC[C@@][C@@H]5C[C@@H]/9[C@]CO))C=O)OC)))C6=Ncc9cccc6
Heavy Atom Count 26.0
Classyfire Class Strychnos alkaloids
Scaffold Graph Node Level CC1CN2CCC34C(CC1CC23)NC1CCCCC14
Isotope Atom Count 0.0
Molecular Complexity 701.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (1R,10S,11S,12E,17S)-12-ethylidene-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraene-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.1
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level C=C1CN2CCC34C(=Nc5ccccc53)CC1CC24
Inchi Key DSOCELULQRKOMA-OQTQPSEISA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms preakuammicine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, CO, COC(C)=O, cN=C(C)C
Compound Name Preakuammicine
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O3/c1-3-13-11-23-9-8-20-14-6-4-5-7-16(14)22-18(20)21(12-24,19(25)26-2)15(13)10-17(20)23/h3-7,15,17,24H,8-12H2,1-2H3/b13-3-/t15-,17-,20+,21-/m0/s1
Smiles C/C=C\1/CN2CC[C@@]34[C@@H]2C[C@@H]1[C@](C3=NC5=CC=CC=C45)(CO)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075