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Apovincamine

PubChem CID: 71204

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Compound Synonyms Apovincamine, 4880-92-6, cis-Apovincamine, Apovincamina, Apovincamine [INN], Apovincaminum [Latin], Apovincamina [Spanish], EINECS 225-491-0, (+)-apovincamine, UNII-504R182ZX7, methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate, 504R182ZX7, Apovincaminum, Methyl (3alpha,16alpha)-eburnamenine-14-carboxylate, (+)-CIS-APOVINCAMINE, CHEBI:2787, Methyl(3alpha,16alpha)-eburnamenine-14-carboxylate, Methyl (13aS,13bS)-13a-ethyl-2,3,4,6,13a,14b-hexahydro-1H-indilol(3.2.1-de)pyrido(3,2,1-ij)(1,5)naphthylridin-12-carboxylat, Apovincaminum (Latin), VINPOCETINE IMPURITY B [EP IMPURITY], Eburnamenine-14-carboxylic acid, methyl ester, (3-alpha,16-alpha)-, Eburnamenine-14-carboxylic acid, methyl ester, (3.alpha.,16.alpha.)-, METHYL(3.ALPHA.,16.ALPHA.)-EBURNAMENINE-14-CARBOXYLATE, Methyl (13aS,13bS)-13a-Ethyl-2,3,5,6,13a,13b-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate (Apovincamine), VINPOCETINE IMPURITY B (EP IMPURITY), Vinpocetine impurity B, methyl(3a,16a)-eburnamenine-14-carboxylate, methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo(9.6.2.02,7.08,18.015,19)nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate, Methyl (3.alpha.,16.alpha.)-eburnamenine-14-carboxylate, Methyl eburnamenine-14-carboxylate, (3.alpha.,16.alpha.)-, SCHEMBL194507, CHEMBL1163488, DTXSID401023598, AKOS040744755, 1ST10857, DA-50650, HY-135743, CS-0113909, NS00045147, C09035, Q15410269, Methyl eburnamenine-14-carboxylate, (3alpha,16alpha)-, (3alpha,16alpha)-Eburnamenine-14-carboxylic Acid Methyl Ester, Eburnamenine-14-carboxylic acid, methyl ester, (3alpha,16alpha)-, 225-491-0
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 34.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CCC3C4CCCCC4C4CCC(C1)C2C34
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)C=C[C@]CC))CCCN[C@@H]6cn%10cccccc6c9CC%13
Heavy Atom Count 25.0
Classyfire Class Eburnan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)C1CCN3CCCC4CCN2C1C43
Isotope Atom Count 0.0
Molecular Complexity 603.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name methyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.8
Gsk 4 400 Rule True
Molecular Formula C21H24N2O2
Scaffold Graph Node Bond Level C1=Cn2c3c(c4ccccc42)CCN2CCCC1C32
Inchi Key OZDNDGXASTWERN-CTNGQTDRSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms apovincamine
Esol Class Moderately soluble
Functional Groups CN(C)C, cn(c)C(=CC)C(=O)OC
Compound Name Apovincamine
Exact Mass 336.184
Formal Charge 0.0
Monoisotopic Mass 336.184
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 336.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O2/c1-3-21-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(18(15)19(21)22)17(13-21)20(24)25-2/h4-5,7-8,13,19H,3,6,9-12H2,1-2H3/t19-,21+/m1/s1
Smiles CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Vinca Minor (Plant) Rel Props:Reference:ISBN:9780387706375