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Cyclocurcumin

PubChem CID: 69879809

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Compound Synonyms Cyclocurcumin, 153127-42-5, CYCLOCURCUMIN(P), CHEMBL4098368, 2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyran-4-one, 2-(4-hydroxy-3-methoxyphenyl)-6-((E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl)-2,3-dihydropyran-4-one, SCHEMBL6727064, SCHEMBL23040676, CHEBI:175723, DTXSID501317744, HY-N8251, BDBM50501397, AKOS040761556, 4H-Pyran-4-one,2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-6-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-, DA-72477, LS-14853, CS-0141880, E80620, (E)-2-(4-hydroxy-3-methoxyphenyl)-6-(4-hydroxy-3-methoxystyryl)-2H-pyran-4(3H)-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 85.2
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(CCC2CCCCC2)CC(C2CCCCC2)C1
Np Classifier Class Linear diarylheptanoids
Deep Smiles COccc/C=C/C=CC=O)CCO6)cccccc6)OC)))O))))))))))))ccc6O
Heavy Atom Count 27.0
Classyfire Class Diarylheptanoids
Description Constituent of the rhizome of Curcuma longa (turmeric). Cyclocurcumin is found in turmeric and herbs and spices.
Scaffold Graph Node Level OC1CC(CCC2CCCCC2)OC(C2CCCCC2)C1
Classyfire Subclass Linear diarylheptanoids
Isotope Atom Count 0.0
Molecular Complexity 571.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P27732
Iupac Name 2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyran-4-one
Prediction Hob 1.0
Class Diarylheptanoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 3.0
Superclass Phenylpropanoids and polyketides
Subclass Linear diarylheptanoids
Gsk 4 400 Rule True
Molecular Formula C21H20O6
Scaffold Graph Node Bond Level O=C1C=C(C=Cc2ccccc2)OC(c2ccccc2)C1
Prediction Swissadme 0.0
Inchi Key IZLBLUIBVMGMIY-ZZXKWVIFSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1904761904761904
Logs -4.222
Rotatable Bond Count 5.0
Logd 3.005
Synonyms cyclocurcumin
Substituent Name Linear 1,7-diphenylheptane skeleton, Methoxyphenol, Methoxybenzene, Styrene, Phenol ether, Anisole, Phenol, Dihydropyranone, Alkyl aryl ether, Benzenoid, Monocyclic benzene moiety, Vinylogous ester, Cyclic ketone, Ketone, Oxacycle, Organoheterocyclic compound, Ether, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aromatic heteromonocyclic compound
Esol Class Moderately soluble
Functional Groups c/C=C/C1=CC(=O)CCO1, cO, cOC
Compound Name Cyclocurcumin
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 368.126
Formal Charge 0.0
Monoisotopic Mass 368.126
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 368.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 True
Esol -4.012875888888889
Inchi InChI=1S/C21H20O6/c1-25-20-9-13(4-7-17(20)23)3-6-16-11-15(22)12-19(27-16)14-5-8-18(24)21(10-14)26-2/h3-11,19,23-24H,12H2,1-2H3/b6-3+
Smiles COC1=C(C=CC(=C1)/C=C/C2=CC(=O)CC(O2)C3=CC(=C(C=C3)O)OC)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Taxonomy Direct Parent Linear diarylheptanoids
Np Classifier Superclass Diarylheptanoids

  • 1. Outgoing r'ship FOUND_IN to/from Curcuma Longa (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all