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Meconin

PubChem CID: 68437

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Compound Synonyms Meconin, 569-31-3, 6,7-dimethoxyisobenzofuran-1(3H)-one, Opianyl, MECONINE, 6,7-Dimethoxy-3H-1-isobenzofuranone, 6,7-Dimethoxyphthalide, Meconic lactone, Mekonin, 6,7-dimethoxy-3H-2-benzofuran-1-one, 6,7-Dimethoxy-2-benzofuran-1(3H)-one, 6,7-Dimethoxy-1(3H)-isobenzofuranone, NSC 35547, Maconine, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-, MFCD00219354, 6,7-dimethoxy-1,3-dihydro-2-benzofuran-1-one, MK5R222CG0, MECONIN [MI], EINECS 209-311-8, NSC-35547, DTXSID60205433, NSC35547, Meconin (1.0 mg/mL in Chloroform), 6,7-dimethoxy-3H-isobenzofuran-1-one, UNII-MK5R222CG0, Meconine (Standard), Phthalide,7-dimethoxy-, 6,7-Dimethoxy-Phthalide, ChemDiv1_018723, Phthalide, 6,7-dimethoxy-, MLS001049120, DivK1c_003507, SCHEMBL698750, CHEMBL1333869, HMS640D01, DTXCID60127924, CHEBI:173937, HMS2267N03, 6,7-dimethoxy 3H-isobenzofuranone, BCP16837, HY-W019151R, AC2115, STL561453, 1(3H)-Isobenzofuranone,7-dimethoxy-, AKOS001376922, 6,7-dimethoxy-3H-2-benzouran-1-one, HY-W019151, CDS1_002467, 6,7-dimethoxyisobenzofuran-1 (3H)-one, NCGC00246213-01, AC-25607, CS-11421, SMR000386950, SY020123, 6,7-dimethoxy-isobenzo-furan-1 (3H)-one, DB-072220, CS-0028244, NS00007888, 6 pound not7-Dimethoxy-3H-1-isobenzofuranone, EN300-7371095, AE-641/30608025, SR-01000388929, SR-01000388929-1, Q27284078, Z234875088, 209-311-8
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 44.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CCCCC12
Np Classifier Class Phthalide derivatives
Deep Smiles COccOC))cccc6C=O)OC5
Heavy Atom Count 14.0
Classyfire Class Isocoumarans
Scaffold Graph Node Level OC1OCC2CCCCC21
Classyfire Subclass Isobenzofuranones
Isotope Atom Count 0.0
Molecular Complexity 228.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P02545, B2RXH2, Q96KQ7, O95149, Q9UNA4, P63092, P37840
Iupac Name 6,7-dimethoxy-3H-2-benzofuran-1-one
Prediction Hob 1.0
Class Isocoumarans
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT483, NPT48
Xlogp 1.3
Superclass Organoheterocyclic compounds
Subclass Isobenzofuranones
Gsk 4 400 Rule True
Molecular Formula C10H10O4
Scaffold Graph Node Bond Level O=C1OCc2ccccc21
Prediction Swissadme 1.0
Inchi Key ORFFGRQMMWVHIB-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.3
Logs -2.171
Rotatable Bond Count 2.0
State Solid
Logd 1.36
Synonyms 6,7-Dimethoxy-1(3H)-isobenzofuranone, 6,7-Dimethoxy-2-benzofuran-1(3H)-one, 6,7-Dimethoxy-3H-isobenzofuran-1-one, 6,7-Dimethoxy-phthalide, 6,7-Dimethoxyphthalide, Maconine, Meconic lactone, Meconin, Mekonin, Opianyl, meconin, meconine
Esol Class Soluble
Functional Groups cC(=O)OC, cOC
Compound Name Meconin
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 194.058
Formal Charge 0.0
Monoisotopic Mass 194.058
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 194.18
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -2.041796057142857
Inchi InChI=1S/C10H10O4/c1-12-7-4-3-6-5-14-10(11)8(6)9(7)13-2/h3-4H,5H2,1-2H3
Smiles COC1=C(C2=C(COC2=O)C=C1)OC
Nring 2.0
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Phthalides
Np Classifier Superclass Cyclic polyketides

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Microstigma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Chrozophora Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Papaver Commutatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Papaver Sommiferum (Plant) Rel Props:Source_db:npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all