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3,4-Dimethoxytoluene

PubChem CID: 68126

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Compound Synonyms 3,4-Dimethoxytoluene, 494-99-5, 1,2-Dimethoxy-4-methylbenzene, Homoveratrole, 4-Methylveratrole, Benzene, 1,2-dimethoxy-4-methyl-, 4-Methylveratrol, 4-Methyl-1,2-dimethoxybenzene, Toluene, 3,4-dimethoxy-, NSC 7378, UNII-349X0G2SSF, MFCD00016651, 349X0G2SSF, Veratrole, 4-methyl-, 3,4-dimethoxy-toluene, NSC-7378, EINECS 207-796-0, CHEMBL273904, DTXSID8060088, 4-METHYLCATECHOL DIMETHYL ETHER, 3,?4-?Dimethoxytoluene, 1,2-Dimethoxy-4-methyl-benzene, 4Methylveratrol, 4Methylveratrole, 4 -methylveratrole, 3.4-dimethoxytoluene, Toluene,4-dimethoxy-, Toluene, 3,4dimethoxy, 4Methyl1,2dimethoxybenzene, SCHEMBL12518, 3,4-Dimethoxytoluene, 96%, Benzene, 1,2dimethoxy4methyl, Benzene,2-dimethoxy-4-methyl-, DTXCID3040691, Toluene, 3,4dimethoxy (8CI), NSC7378, AC8401, BDBM50008536, AKOS000120780, CS-W018091, FD71359, AS-15527, SY012769, DB-021933, D1986, NS00022236, EN300-16175, Q27256350, Z54180242, Homoveratrole, 4-Methylveratrole, 4-Methyl 1,2-dimethoxybenzene, 207-796-0
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 18.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Deep Smiles COcccC)ccc6OC
Heavy Atom Count 11.0
Classyfire Class Benzene and substituted derivatives
Description 1,2-dimethoxy-4-methylbenzene is a member of the class of compounds known as dimethoxybenzenes. Dimethoxybenzenes are organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups. 1,2-dimethoxy-4-methylbenzene is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 1,2-dimethoxy-4-methylbenzene can be found in tea, which makes 1,2-dimethoxy-4-methylbenzene a potential biomarker for the consumption of this food product.
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Methoxybenzenes
Isotope Atom Count 0.0
Molecular Complexity 114.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22303
Iupac Name 1,2-dimethoxy-4-methylbenzene
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT204
Xlogp 1.9
Superclass Benzenoids
Subclass Methoxybenzenes
Gsk 4 400 Rule True
Molecular Formula C9H12O2
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key GYPMBQZAVBFUIZ-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.3333333333333333
Logs -2.299
Rotatable Bond Count 2.0
State liquid
Logd 2.385
Synonyms 1,2-Dimethoxy-4-methyl-benzene, 1,2-Dimethoxy-4-methyl-benzene (4-methylveratrol), 1,2-Dimethoxy-4-methylbenzene, 9CI, 3, 4-Dimethoxytoluene, 3,4-Dimethoxytoluene, 3,4-Dimethoxytoluene, 8CI, 4-Methyl-1,2-dimethoxybenzene, 4-Methylveratrol, 4-Methylveratrole, Benzene, 1,2-dimethoxy-4-methyl-, Homoveratrole, Methyl veratrol, Toluene, 3, 4-dimethoxy-, Toluene, 3,4-dimethoxy-, Toluene, 3,4-dimethoxy- (8CI), 1,2-Dimethoxy-4-methylbenzene, 3, 4-dimethoxytoluene, 3,4-dimethoxytoluene
Esol Class Soluble
Functional Groups cOC
Compound Name 3,4-Dimethoxytoluene
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 152.084
Formal Charge 0.0
Monoisotopic Mass 152.084
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 152.19
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -2.1955329636363636
Inchi InChI=1S/C9H12O2/c1-7-4-5-8(10-2)9(6-7)11-3/h4-6H,1-3H3
Smiles CC1=CC(=C(C=C1)OC)OC
Nring 1.0
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Dimethoxybenzenes

  • 1. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Euryale Ferox (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2019.1595165
  • 3. Outgoing r'ship FOUND_IN to/from Handroanthus Impetiginosus (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.1345
  • 4. Outgoing r'ship FOUND_IN to/from Myroxylon Peruiferum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Picea Abies (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2007.9699244