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17-Hydroxyjolkinolide A

PubChem CID: 6712606

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Compound Synonyms 17-hydroxyjolkinolide A, CHEBI:69826, (1S,3R,10S,11R,16R)-5-(hydroxymethyl)-11,15,15-trimethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one, (1S,3R,10S,11R,16R)-5-(hydroxymethyl)-11,15,15-trimethyl-2,7-dioxapentacyclo(8.8.0.01,3.04,8.011,16)octadeca-4,8-dien-6-one, NCI60_035895, CHEMBL1988221, HY-N12428, NSC700086, NSC-700086, CS-0906566, Q27138167
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 59.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CC3C4CCCCC4CCC34CC4C2C1
Np Classifier Class Furanoabietane diterpenoids
Deep Smiles OCC=CC=C[C@@H][C@][C@@H]6O3))CC[C@H][C@@]6C)CCCC6C)C))))))))))))OC5=O
Heavy Atom Count 24.0
Classyfire Class Naphthofurans
Scaffold Graph Node Level OC1CC2C(CC3C4CCCCC4CCC34OC24)O1
Isotope Atom Count 0.0
Molecular Complexity 702.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Uniprot Id n.a.
Iupac Name (1S,3R,10S,11R,16R)-5-(hydroxymethyl)-11,15,15-trimethyl-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadeca-4,8-dien-6-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.2
Gsk 4 400 Rule True
Molecular Formula C20H26O4
Scaffold Graph Node Bond Level O=C1C=C2C(=CC3C4CCCCC4CCC34OC24)O1
Prediction Swissadme 1.0
Inchi Key DIJWCRKTZVUBDY-PHJMNMFVSA-N
Silicos It Class Soluble
Fcsp3 0.75
Logs -4.387
Rotatable Bond Count 1.0
Logd 3.319
Synonyms caudicifolin
Esol Class Soluble
Functional Groups CC1=C2C(=CC[C@]3(C)O[C@H]23)OC1=O, CO
Compound Name 17-Hydroxyjolkinolide A
Prediction Hob Swissadme 1.0
Exact Mass 330.183
Formal Charge 0.0
Monoisotopic Mass 330.183
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 330.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.8197288000000005
Inchi InChI=1S/C20H26O4/c1-18(2)6-4-7-19(3)13(18)5-8-20-14(19)9-12-15(16(20)24-20)11(10-21)17(22)23-12/h9,13-14,16,21H,4-8,10H2,1-3H3/t13-,14+,16-,19-,20+/m1/s1
Smiles C[C@@]12CCCC([C@H]1CC[C@]34[C@H]2C=C5C(=C(C(=O)O5)CO)[C@H]3O4)(C)C
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Euphorbia Antiquorum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Euphorbia Caducifolia (Plant) Rel Props:Reference:ISBN:9788172362300
  • 3. Outgoing r'ship FOUND_IN to/from Euphorbia Ebracteolata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Euphorbia Fischeriana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Euphorbia Fusiformis (Plant) Rel Props:Reference:ISBN:9788172362300; ISBN:9788185042138
  • 6. Outgoing r'ship FOUND_IN to/from Euphorbia Wallichii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all