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3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

PubChem CID: 662

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Compound Synonyms 724434-08-6, (+/-)-Dihydrokaempferol, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one, 3,5,7,4''-TETRAHYDROXYFLAVANONE, 104486-98-8, 4H-1-Benzopyran-4-one,2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, trans-, 5150-32-3, KAEMPFEROL_met008, SCHEMBL39319, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one, CHEMBL398847, DTXSID50274279, PADQINQHPQKXNL-UHFFFAOYSA-N, BCP20472, NSC327432, 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, AKOS032948350, AT25341, NSC-327432, NCGC00488813-01, NS00134207, 2,3-Dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, , 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one #, 4H-1-Benzopyran-4-one,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-
Topological Polar Surface Area 107.0
Hydrogen Bond Donor Count 4.0
Heavy Atom Count 21.0
Description Dihydrokaempferol, also known as aromadendrin, is a member of the class of compounds known as flavanonols. Flavanonols are compounds containing a flavan-3-one moiety, with a structure characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a hydroxyl group and a ketone at the carbon C2 and C3, respectively. Dihydrokaempferol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Dihydrokaempferol can be found in european plum and tea, which makes dihydrokaempferol a potential biomarker for the consumption of these food products. Aromadendrin (aromodedrin or dihydrokaempferol) is a flavanonol, a type of flavonoid. It can be found in the wood of Pinus sibirica .
Isotope Atom Count 0.0
Molecular Complexity 392.0
Database Name cmaup_ingredients;fooddb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q9JM51, Q60795
Iupac Name 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Prediction Hob 1.0
Xlogp 1.8
Molecular Formula C15H12O6
Prediction Swissadme 0.0
Inchi Key PADQINQHPQKXNL-UHFFFAOYSA-N
Fcsp3 0.1333333333333333
Logs -2.725
Rotatable Bond Count 1.0
Logd 0.259
Synonyms 2,3-Dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 9CI, 3-Hydroxynaringenin, 3,4',5,7-Tetrahydroxyflavanone, 4',5,7-Trihydroxydihydroflavonol, Dihydrokaempferol
Compound Name 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Prediction Hob Swissadme 0.0
Exact Mass 288.063
Formal Charge 0.0
Monoisotopic Mass 288.063
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 288.25
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Esol -2.8093381428571425
Inchi InChI=1S/C15H12O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,14-18,20H
Smiles C1=CC(=CC=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
Nring 3.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Hovenia Dulcis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Morus Alba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Prunus Davidiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Prunus Domestica (Plant) Rel Props:Source_db:fooddb_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Prunus Persica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all