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Reserpic acid

PubChem CID: 65747

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Compound Synonyms Reserpic acid, Reserpinolic acid, 83-60-3, UNII-K6L9W0QP1W, K6L9W0QP1W, CHEBI:46690, NSC 81463, NSC-81463, RESERPIC ACID [MI], CHEMBL411716, DTXSID50232112, NSC81463, (1R,15S,17R,18R,19S,20S)-17-hydroxy-6,18-dimethoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid, (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylic acid, 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, Yohimban-16-carboxylic acid, 18-hydroxy-11,17-dimethoxy-, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-, Yohimban-16-carboxylic acid, 18-hydroxy-11,17-dimethoxy-, (3beta,16beta,17alpha,18beta,20alpha)-, Reserpinolate, Reserpinsaure, Reserpate, Prestwick0_000984, Prestwick1_000984, Prestwick2_000984, Prestwick3_000984, BSPBio_001047, SCHEMBL571464, SPBio_002948, BPBio1_001153, DTXCID50154603, BDBM50374533, FR65662, NCI60_041786, AB00514690, Q1690907, 3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy-, BRD-K32755366-003-03-4, 18b-Hydroxy-11,17a-dimethoxy-3b,20a-yohimban-16b-carboxylate, 18b-Hydroxy-11,17a-dimethoxy-3b,20a-yohimban-16b-carboxylic acid, 18beta-Hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate, 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-(8CI), Yohimban-16-carboxylic acid, 18-hydroxy-11,17-dimethoxy-, (3beta,16beta,17alpha,18beta,20alpha)-(9CI), Yohimban-16-carboxylic acid,17-dimethoxy-, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 95.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles CO[C@H][C@H]O)C[C@H][C@@H][C@@H]6C=O)O)))C[C@H]NC6)CCcc6[nH]cc5cccc6)OC
Heavy Atom Count 29.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level C1CCC2CN3CCC4C5CCCCC5NC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 632.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (1R,15S,17R,18R,19S,20S)-17-hydroxy-6,18-dimethoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp -0.7
Gsk 4 400 Rule False
Molecular Formula C22H28N2O5
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCCCC2CN1CC3
Inchi Key JVHNBFFHWQQPLL-WOXROFTLSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms reserpic acid
Esol Class Very soluble
Functional Groups CC(=O)O, CN(C)C, CO, COC, cOC, c[nH]c
Compound Name Reserpic acid
Exact Mass 400.2
Formal Charge 0.0
Monoisotopic Mass 400.2
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 400.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H28N2O5/c1-28-12-3-4-13-14-5-6-24-10-11-7-18(25)21(29-2)19(22(26)27)15(11)9-17(24)20(14)23-16(13)8-12/h3-4,8,11,15,17-19,21,23,25H,5-7,9-10H2,1-2H3,(H,26,27)/t11-,15+,17-,18-,19+,21+/m1/s1
Smiles CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)O)NC5=C4C=CC(=C5)OC)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075