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Phosphodiesterase 4 Inhibitors

PubChem CID: 656969

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Compound Synonyms Phosphodiesterase 4 Inhibitor, 346440-86-6, 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, ethyl 3,5-dimethyl-1-(3-nitrophenyl)pyrazole-4-carboxylate, DTXSID70349675, ethyl 3,5-dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylate, 1H-Pyrazole-4-carboxylicacid, 3,5-dimethyl-1-(3-nitrophenyl)-, ethyl ester, 7DE, 3,5-Dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester, Inhibitor, PDE4, PDE 4 Inhibitor, Inhibitors, PDE4, PDE 4 Inhibitors, Inhibitor, PDE-4, Inhibitors, PDE-4, Phosphodiesterase 4 Inhibitors, 4 Inhibitor, Phosphodiesterase, Inhibitor, Phosphodiesterase 4, Inhibitors, Phosphodiesterase 4, Phosphodiesterase Type 4 Inhibitor, Phosphodiesterase 4, Phosphodiesterase Type 4 Inhibitors, 1y2j, 1y2k, Pyrazole carboxylic ester 21, phosphodiesterase IV inhibitor, phosphodiesterase IV inhibitors, SCHEMBL2201643, CHEMBL1230564, BDBM14798, CHEBI:68844, DTXCID10300745, MSYGAHOHLUJIKV-UHFFFAOYSA-N, type 4 phosphodiesterase inhibitor, type 4 phosphodiesterase inhibitors, AKOS040754989, DB01959, NCGC00387777-01, DB-114471, NS00068179, Q27093055
Topological Polar Surface Area 89.9
Hydrogen Bond Donor Count 0.0
Inchi Key MSYGAHOHLUJIKV-UHFFFAOYSA-N
Rotatable Bond Count 4.0
Heavy Atom Count 21.0
Compound Name Phosphodiesterase 4 Inhibitors
Description 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester is a member of the class of compounds known as phenylpyrazoles. Phenylpyrazoles are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester is practically insoluble (in water) and a moderately basic compound (based on its pKa). 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester can be found in a number of food items such as common wheat, yellow bell pepper, green bell pepper, and common grape, which makes 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester a potential biomarker for the consumption of these food products.
Exact Mass 289.106
Formal Charge 0.0
Monoisotopic Mass 289.106
Isotope Atom Count 0.0
Molecular Complexity 398.0
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 289.29
Database Name fooddb_chem_all;pubchem
Covalent Unit Count 1.0
Defined Atom Stereocenter Count 0.0
Iupac Name ethyl 3,5-dimethyl-1-(3-nitrophenyl)pyrazole-4-carboxylate
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Inchi InChI=1S/C14H15N3O4/c1-4-21-14(18)13-9(2)15-16(10(13)3)11-6-5-7-12(8-11)17(19)20/h5-8H,4H2,1-3H3
Smiles CCOC(=O)C1=C(N(N=C1C)C2=CC(=CC=C2)[N+](=O)[O-])C
Xlogp 2.7
Defined Bond Stereocenter Count 0.0
Molecular Formula C14H15N3O4

  • 1. Outgoing r'ship FOUND_IN to/from Capsicum Annuum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Triticum Aestivum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Vitis Vinifera (Plant) Rel Props:Source_db:fooddb_chem_all