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Tomatidine

PubChem CID: 65576

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Compound Synonyms Tomatidine, 77-59-8, Tomatidin, (3beta,5alpha,22beta,25S)-Spirosolan-3-ol, EINECS 201-040-3, NSC 27592, NSC 226903, CHEBI:9629, UNII-2B73S48786, TOMATIDINE [MI], 5alpha-Tomatidan-3beta-ol, (22S,25S)-5alpha-spirosolan-3beta-ol, 2B73S48786, DTXSID0037102, Spirosolan-3-ol, (3beta,5alpha,22beta,25S)-, NSC-27592, (3beta,5alpha,25S)-spirosolan-3-ol, NSC-226903, (1R,2S,4S,5'S,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-piperidine]-16-ol, SMR001233234, 5a-Tomatidan-3b-ol, 8CI, Spirosolan-3-ol, (3.beta.,5.alpha.,22.beta.,25S)-, 5.alpha.-Tomatidan-3.beta.-ol, SR-05000002324, (1R,2S,4S,5'S,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icosane-6,2'-piperidine)-16-ol, Prestwick_473, MFCD00075644, Prestwick3_000573, BSPBio_000386, (3 beta,5 alpha,22 beta, 25S)-spirosolan-3-ol, MLS002153880, MLS002222215, SCHEMBL335093, BPBio1_000426, CHEMBL2165711, DTXCID8017102, XYNPYHXGMWJBLV-VXPJTDKGSA-N, HMS2096D08, HY-N2149, AKOS040760056, CCG-208279, CS-5821, SMP1_000126, NCGC00179576-01, AC-34219, FS137974, NS00018364, SR-05000002324-3, Q27108452, Spirosolan-3-ol, (3alpha,22alpha-tomatidan-3beta-ol, Spirosolan-3-ol, (3beta,5alpha,22beta,25S)-(9ci), 5 alpha,20 beta(F),22 alpha(F),25 beta(F),27-Azaspirostan-3 beta-ol, 201-040-3
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2(CC1)CC1CC3C(CCC4C5CCCCC5CCC43)C1C2
Np Classifier Class Steroidal alkaloids
Deep Smiles C[C@H]CC[C@]NC6))O[C@@H][C@H][C@@H]5C))[C@@][C@@H]C5)[C@@H]CC[C@@H][C@][C@H]6CC%10)))C)CC[C@@H]C6)O))))))))))C
Heavy Atom Count 30.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)NC1
Classyfire Subclass Steroidal alkaloids
Isotope Atom Count 0.0
Molecular Complexity 696.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 12.0
Iupac Name (1R,2S,4S,5'S,6S,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-piperidine]-16-ol
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 6.2
Gsk 4 400 Rule False
Molecular Formula C27H45NO2
Scaffold Graph Node Bond Level C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)NC1
Inchi Key XYNPYHXGMWJBLV-VXPJTDKGSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 0.0
Synonyms tomatidine
Esol Class Poorly soluble
Functional Groups CN[C@](C)(C)OC, CO
Compound Name Tomatidine
Exact Mass 415.345
Formal Charge 0.0
Monoisotopic Mass 415.345
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 415.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 12.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C27H45NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28-29H,5-15H2,1-4H3/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27-/m0/s1
Smiles C[C@H]1CC[C@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)O)C)C)C)NC1
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Chlorophytum Tuberosum (Plant) Rel Props:Reference:ISBN:9788171360536
  • 2. Outgoing r'ship FOUND_IN to/from Lycopersicon Esculentum (Plant) Rel Props:Reference:ISBN:9780896038776
  • 3. Outgoing r'ship FOUND_IN to/from Solanum Anguivi (Plant) Rel Props:Reference:ISBN:9788172361150
  • 4. Outgoing r'ship FOUND_IN to/from Solanum Dulcamara (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/5469395