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O-Methylpsychotrine

PubChem CID: 65033

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Compound Synonyms O-Methylpsychotrine, Methylpsychotrine, Methylpsychotrin, 1',2'-Dehydroemetin, 523-01-3, UNII-V7C64CD3BR, EINECS 208-339-8, V7C64CD3BR, Emetan, 1',2'-didehydro-6',7',10,11-tetramethoxy-, O-methyl-psychotrine, CHEBI:81067, 1',2'-DEHYDROEMETINE, CHEMBL471812, O-METHYLPSYCHOTRINE [MI], DTXSID70200318, (2R,3R,11bS)-2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine, 2H-Benzo[a]quinolizine, 2-[(3,4-dihydro-6,7-dimethoxy-1-isoquinolinyl)methyl]-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-, (2R,3R,11bS)-, 2H-BENZO(A)QUINOLIZINE, 2-((3,4-DIHYDRO-6,7-DIMETHOXY-1-ISOQUINOLINYL)METHYL)-3-ETHYL-1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-, (2R,3R,11BS)-, (2R,3R,11bS)-2-((6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo(a)quinolizine, Psychotrine, O-methyl-, SCHEMBL181482, DTXCID70122809, FBRKYRSUSJWLHH-HMHJJOSWSA-N, Psychotrine, O-methyl-(6CI,7CI), BDBM50478516, O-methylpsychotrine sulfate hepatahydrate, NS00032476, C17411, AK-693/43462589, Q27155023, 208-339-8
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 52.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCCC2CC1CCC2CCC3CCCCC3C2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles CC[C@H]CNCCcc[C@@H]6C[C@@H]%10CC=NCCcc6ccOC))cc6)OC)))))))))))))))cccc6)OC)))OC
Heavy Atom Count 35.0
Classyfire Class Emetine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCNC2CC1CCN2CCC3CCCCC3C2C1
Isotope Atom Count 0.0
Molecular Complexity 731.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id Q72547
Iupac Name (2R,3R,11bS)-2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.6
Gsk 4 400 Rule False
Molecular Formula C29H38N2O4
Scaffold Graph Node Bond Level c1ccc2c(c1)CCN=C2CC1CCN2CCc3ccccc3C2C1
Prediction Swissadme 1.0
Inchi Key FBRKYRSUSJWLHH-HMHJJOSWSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5517241379310345
Logs -4.603
Rotatable Bond Count 7.0
Logd 4.097
Synonyms o-methylpsychotrine
Esol Class Moderately soluble
Functional Groups CN(C)C, cC(C)=NC, cOC
Compound Name O-Methylpsychotrine
Prediction Hob Swissadme 0.0
Exact Mass 478.283
Formal Charge 0.0
Monoisotopic Mass 478.283
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 478.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.503488485714287
Inchi InChI=1S/C29H38N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,25H,6-12,17H2,1-5H3/t18-,21-,25-/m0/s1
Smiles CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1CC4=NCCC5=CC(=C(C=C54)OC)OC)OC)OC
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Carapichea Ipecacuanha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Mentha Aquatica (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Tragopogon Porrifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all