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methyl (10S,12R,13E,18S)-13-ethylidene-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate

PubChem CID: 6444325

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC34CC1CC2C3CC1CCCCC14
Np Classifier Class Corynanthe type
Deep Smiles COC=O)[C@H][C@H]C[C@H]C=NccC95CCN9C/C/%13=C/C))))))))cccc6
Heavy Atom Count 24.0
Classyfire Class Akuammilan and related alkaloids
Scaffold Graph Node Level CC1CN2CCC34CC1CC2C3NC1CCCCC14
Isotope Atom Count 0.0
Molecular Complexity 640.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name methyl (10S,12R,13E,18S)-13-ethylidene-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C20H22N2O2
Scaffold Graph Node Bond Level C=C1CN2CCC34CC1CC2C3=Nc1ccccc14
Inchi Key LITYYRLWHAQJQS-PHDDPKRUSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms strictamine, vincamidine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, COC(C)=O, cN=C(C)C
Compound Name methyl (10S,12R,13E,18S)-13-ethylidene-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
Exact Mass 322.168
Formal Charge 0.0
Monoisotopic Mass 322.168
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 322.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H22N2O2/c1-3-12-11-22-9-8-20-14-6-4-5-7-15(14)21-18(20)16(22)10-13(12)17(20)19(23)24-2/h3-7,13,16-17H,8-11H2,1-2H3/b12-3-/t13-,16-,17+,20?/m0/s1
Smiles C/C=C\1/CN2CCC34[C@H]([C@H]1C[C@H]2C3=NC5=CC=CC=C45)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

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