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Neo-gambogic acid

PubChem CID: 6438568

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Compound Synonyms Neogambogic acid, Neo-gambogic acid, 93772-31-7, (E)-4-[10,12-dihydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,11,15-tetraen-19-yl]-2-methylbut-2-enoic acid, 2-Butenoic acid, 4-(3a,4,5,7,10,11-hexahydro-8,9-dihydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,9H-furo(3,4-g)pyrano(3,2-b)xanthen-1-yl)-2-methyl-, AKOS040758796, FN11496, FS-6930, 1428127-36-9, 4-(8,9-Dihydroxy-2,2,11-trimethyl-13-(3-methylbut-2-en-1-yl)-11-(4-methylpent-3-en-1-yl)-4,7-dioxo-1,2,5,7,10,11-hexahydro-9H-1,5-methanofuro[3,2-g]pyrano[3,2-b]xanthen-3a(4H)-yl)-2-methylbut-2-enoic acid
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 140.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CC3CCC1C31CC3CC4CCCCC4CC3C(C)C1C2
Np Classifier Class Plant xanthones
Deep Smiles CC=CCccOCC=CCCC6COC9C/C=C/C=O)O))C))))C7=O))))C)C))))))C=O)c6ccc%10OCC)CCC=CC)C)))))CC6O)))))))O)))))))))))C
Heavy Atom Count 47.0
Classyfire Class Benzopyrans
Scaffold Graph Node Level OC1C2CC3CCCOC3CC2OC23C4COC2C(O)C(C4)CC13
Classyfire Subclass 1-benzopyrans
Isotope Atom Count 0.0
Molecular Complexity 1480.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (E)-4-[10,12-dihydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,11,15-tetraen-19-yl]-2-methylbut-2-enoic acid
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 6.3
Gsk 4 400 Rule False
Molecular Formula C38H46O9
Scaffold Graph Node Bond Level O=C1C2=CC3CC4COC(C3=O)C24Oc2cc3c(cc21)CCCO3
Prediction Swissadme 0.0
Inchi Key BLDWFKHVHHINGR-FYJGNVAPSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5526315789473685
Logs -1.169
Rotatable Bond Count 8.0
Logd -0.346
Synonyms neogambogic-acid
Esol Class Poorly soluble
Functional Groups C/C=C(C)C(=O)O, CC(C)=O, CC=C(C)C, CO, COC, cC(=O)C(C)=CC, cO, cOC
Compound Name Neo-gambogic acid
Prediction Hob Swissadme 0.0
Exact Mass 646.314
Formal Charge 0.0
Monoisotopic Mass 646.314
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 646.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 False
Esol -7.372885485106385
Inchi InChI=1S/C38H46O9/c1-19(2)10-9-14-36(8)18-25(39)27-30(41)28-29(40)24-16-22-17-26-35(6,7)47-37(33(22)42,15-13-21(5)34(43)44)38(24,26)46-32(28)23(31(27)45-36)12-11-20(3)4/h10-11,13,16,22,25-26,39,41H,9,12,14-15,17-18H2,1-8H3,(H,43,44)/b21-13+
Smiles CC(=CCCC1(CC(C2=C(C3=C(C(=C2O1)CC=C(C)C)OC45C6CC(C=C4C3=O)C(=O)C5(OC6(C)C)C/C=C(\C)/C(=O)O)O)O)C)C
Nring 1.0
Np Classifier Biosynthetic Pathway Polyketides, Shikimates and Phenylpropanoids, Terpenoids
Defined Bond Stereocenter Count 1.0
Egan Rule False
Np Classifier Superclass Xanthones

  • 1. Outgoing r'ship FOUND_IN to/from Garcinia Hanburyi (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 2. Outgoing r'ship FOUND_IN to/from Garcinia Morella (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all