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2-Butenoic acid, 2-methyl-, 2,3,5,7a-tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl ester, [1S-[1alpha(Z),7aalpha]]-

PubChem CID: 6432671

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Compound Synonyms 2-Butenoic acid, 2-methyl-, 2,3,5,7a-tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl ester, [1S-[1.alpha.(Z),7a.alpha.]]-, Heliotridine, 7-angelate, Heliotridine, 7-angelyl-, Heliotridine, 7-angelate (ester), Heliotridine, 7-(2-methylcrotonate), (Z)-, TYGYPIIOOQNWBU-SPVDEYDNSA-N, DTXSID001019874, 7-(Hydroxymethyl)-(1S,7aR)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl (2Z)-2-methyl-2-butenoate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CCCC2C1
Np Classifier Class Pyrrolizidine alkaloids
Deep Smiles C/C=CC))/C=O)O[C@H]CCNC5C=CC5))CO
Heavy Atom Count 17.0
Scaffold Graph Node Level C1CC2CCCN2C1
Isotope Atom Count 0.0
Molecular Complexity 373.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name [(1S)-7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-yl] (E)-2-methylbut-2-enoate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.5
Gsk 4 400 Rule True
Molecular Formula C13H19NO3
Scaffold Graph Node Bond Level C1=CC2CCCN2C1
Prediction Swissadme 1.0
Inchi Key TYGYPIIOOQNWBU-SPVDEYDNSA-N
Silicos It Class Soluble
Fcsp3 0.6153846153846154
Logs -1.088
Rotatable Bond Count 4.0
Logd 1.36
Synonyms 7-angelylheliotridine
Esol Class Very soluble
Functional Groups C/C=C(C)C(=O)OC, CC=C(C)C, CN(C)C, CO
Compound Name 2-Butenoic acid, 2-methyl-, 2,3,5,7a-tetrahydro-7-(hydroxymethyl)-1H-pyrrolizin-1-yl ester, [1S-[1alpha(Z),7aalpha]]-
Prediction Hob Swissadme 1.0
Exact Mass 237.136
Formal Charge 0.0
Monoisotopic Mass 237.136
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 237.29
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -1.8536537999999998
Inchi InChI=1S/C13H19NO3/c1-3-9(2)13(16)17-11-5-7-14-6-4-10(8-15)12(11)14/h3-4,11-12,15H,5-8H2,1-2H3/b9-3+/t11-,12?/m0/s1
Smiles C/C=C(\C)/C(=O)O[C@H]1CCN2C1C(=CC2)CO
Nring 2.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Cynoglossum Zeylanicum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Heliotropium Curassavicum (Plant) Rel Props:Reference:ISBN:9788172360481
  • 3. Outgoing r'ship FOUND_IN to/from Heliotropium Ovalifolium (Plant) Rel Props:Reference:ISBN:9788172362300
  • 4. Outgoing r'ship FOUND_IN to/from Nicotiana Tabacum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Senecio Rivularis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Solanum Tuberosum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all