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Isosafrole

PubChem CID: 637796

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Compound Synonyms ISOSAFROLE, Izosafrol, beta-Isosafrole, 120-58-1, Isosafrol, (E)-Isosafrole, RCRA waste number U141, trans-Isosafrole, 5-(1-Propenyl)-1,3-benzodioxole, 4-Propenyl-1,2-methylenedioxybenzene, 1,3-Benzodioxole, 5-(1-propenyl)-, 4-Propenylcatechol methylene ether, Isosafrole (TGMX), NSC 4884, 5-[(E)-prop-1-enyl]-1,3-benzodioxole, 6-(1-Propenyl)-1,3-benzodioxole, CCRIS 353, 1,2-Methylenedioxy-4-propenylbenzene, Benzene, 1,2-(methylenedioxy)-4-propenyl-, 4043-71-4, 3,4-(Methylenedioxy)-1-propenylbenzene, HSDB 2862, EINECS 204-410-2, .beta.-Isosafrole, 1,3-Benzodioxole, 5-(1-propenyl)-, (E)-, 3,4-Methylenedioxy-1-propenyl benzene, BRN 0082640, Benzene, 1,2-(methylenedioxy)-4-propenyl-, (E)-, 5-[(E)-prop-1-enyl]benzo[1,3]dioxole, AI3-02068, trans-1,2-(Methylenedioxy)-4-propenylbenzene, DTXCID00767, 1,3-Benzodioxole, 5-(1-propen-1-yl)-, MLS001055464, 94BY31ALL6, CHEBI:6054, DTXSID2020767, 5-[(1E)-prop-1-en-1-yl]-1,3-benzodioxole, 5-19-01-00552 (Beilstein Handbook Reference), W6337429LF, 5-Prop-1-enyl-1,3-benzodioxole, SMR001227197, ISOSAFROLE (IARC), ISOSAFROLE [IARC], 1,2-(Methylenedioxy)-4-propenylbenzene, 5-[(1E)-prop-1-en-1-yl]-2H-1,3-benzodioxole, CAS-120-58-1, 5-((E)-prop-1-enyl)-1,3-benzodioxole, 5-((1E)-prop-1-en-1-yl)-2H-1,3-benzodioxole, RCRA waste no. U141, UNII-94BY31ALL6, NSC-4884, UNII-W6337429LF, 5-(1-Propen-1-yl)-1,3-benzodioxole, 5-((1E)-1-propenyl)-1,3-benzodioxole, ISOSAFROLE [MI], Spectrum5_000388, ISOSAFROLE [HSDB], ISOSAFROLE, TRANS-, 1,3-Benzodioxole, 5-(1E)-1-propen-1-yl-, BSPBio_002813, SPECTRUM300533, 5(1Propenyl)1,3benzodioxole, 6(1Propenyl)1,3benzodioxole, SCHEMBL266169, ISOSAFROLE (PROHIBITED), CHEMBL487603, cid_637796, 1,3Benzodioxole, 5(1propenyl), 4Propenylcatechol methylene ether, BDBM74206, 1,2Methylenedioxy4propenylbenzene, 4Propenyl1,2methylenedioxybenzene, 3,4Methylenedioxy1propenyl benzene, DTXSID201316597, HMS1373B16, ISOSAFROLE TRANS-FORM [MI], 3,4(Methylenedioxy)1propenylbenzene, 3,4-(Methylenedioxy)propenylbenzene, Tox21_201783, Tox21_302946, 5-trans-propenyl-benzo-1,3-dioxole, BBL027540, CCG-38570, STK801280, AKOS001684145, ISOSAFROLE (PROHIBITED) [FHFI], SDCCGMLS-0066561.P001, 4-PROPENYLCATECHOLMETHYLENE ETHER, NCGC00090700-01, NCGC00090700-02, NCGC00090700-03, NCGC00090700-04, NCGC00090700-05, NCGC00090700-06, NCGC00256538-01, NCGC00259332-01, 1,3-BENZODIOXOLE,5-(1-PROPENYL)-, 3,4-METHYLENEDIOXY-1-PROPENYLBENZENE, 5-(PROPEN-1-YL)-1,3-BENZODIOXOLE, 5-[(1E)-1-Propenyl]-1,3-benzodioxole #, BENZENE,1,2-(METHYLENEDIOXY)-4-PROPENYL, SR-05000002391, Q1088741, SR-05000002391-1, BRD-K44005821-001-07-4, InChI=1/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2-6H,7H2,1H3/b3-2
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 18.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CCCC2C1
Np Classifier Class Cinnamic acids and derivatives
Deep Smiles C/C=C/cccccc6)OCO5
Heavy Atom Count 12.0
Classyfire Class Benzodioxoles
Scaffold Graph Node Level C1CCC2OCOC2C1
Isotope Atom Count 0.0
Molecular Complexity 177.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q13315, P08684, Q9UIF8, P10275, Q03181, Q96RI1, Q16236, P51449, P11308, Q9NUW8, Q9Y6L6, Q9NPD5
Iupac Name 5-[(E)-prop-1-enyl]-1,3-benzodioxole
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT524, NPT109
Xlogp 3.1
Gsk 4 400 Rule True
Molecular Formula C10H10O2
Scaffold Graph Node Bond Level c1ccc2c(c1)OCO2
Prediction Swissadme 0.0
Inchi Key VHVOLFRBFDOUSH-NSCUHMNNSA-N
Silicos It Class Soluble
Fcsp3 0.2
Logs -3.165
Rotatable Bond Count 1.0
Logd 2.629
Synonyms iso-safrole, isosafrol, isosafrole, isosafrolet
Esol Class Soluble
Functional Groups c/C=C/C, c1cOCO1
Compound Name Isosafrole
Prediction Hob Swissadme 0.0
Exact Mass 162.068
Formal Charge 0.0
Monoisotopic Mass 162.068
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 162.18
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -3.4490656
Inchi InChI=1S/C10H10O2/c1-2-3-8-4-5-9-10(6-8)12-7-11-9/h2-6H,7H2,1H3/b3-2+
Smiles C/C=C/C1=CC2=C(C=C1)OCO2
Nring 2.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Phenylpropanoids (C6-C3)

  • 1. Outgoing r'ship FOUND_IN to/from Angelica Acutiloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Artemisia Rupestris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Asarum Heterotropoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Asarum Sieboldii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Cananga Odorata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Cinnamomum Verum (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2016.1212738
  • 7. Outgoing r'ship FOUND_IN to/from Citrus Reticulata (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2006.9699197
  • 8. Outgoing r'ship FOUND_IN to/from Citrus Sinensis (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2009.10643687
  • 9. Outgoing r'ship FOUND_IN to/from Lantana Camara (Plant) Rel Props:Reference:https://doi.org/10.1002/(sici)1099-1026(199901/02)14:1<15::aid-ffj777>3.0.co;2-m
  • 10. Outgoing r'ship FOUND_IN to/from Murraya Koenigii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Myristica Fragrans (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all