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Glaudine

PubChem CID: 633491

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Compound Synonyms Glaudine, Oreodine, (+)-Oreodine, 11,16,17-trimethoxy-22-methyl-6,8,12-trioxa-22-azapentacyclo[11.9.0.0^{2,10}.0^{5,9}.0^{14,19}]docosa-2(10),3,5(9),14,16,18-hexaene, 11,16,17-trimethoxy-22-methyl-6,8,12-trioxa-22-azapentacyclo[11.9.0.02,10.05,9.014,19]docosa-2(10),3,5(9),14,16,18-hexaene, 11,16,17-trimethoxy-22-methyl-6,8,12-trioxa-22-azapentacyclo(11.9.0.0^(2,10).0^(5,9).0^(14,19))docosa-2(10),3,5(9),14,16,18-hexaene, 11,16,17-trimethoxy-22-methyl-6,8,12-trioxa-22-azapentacyclo(11.9.0.02,10.05,9.014,19)docosa-2(10),3,5(9),14,16,18-hexaene, N-Methylpapaverrubine B, O,N-Dimethylporphyroxine, O,N-Dimethylpapaverrubine D, CHEBI:191803, STJFYCWYHROASW-UHFFFAOYSA-N, 1,3-Dioxolo[7,8][2]benzopyrano[3,4-a][3]benzazepine, rheadan deriv., Rheadan, 2,3,8-trimethoxy-16-methyl-10,11-[methylenebis(oxy)]-, (8.beta.)-, 10,11,14-Trimethoxy-6-methyl-5b,6,7,8,12b,14-hexahydro[1,3]dioxolo[4',5':7,8]isochromeno[3,4-a][3]benzazepine #
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 58.6
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCCC1C2CCC2C3CCCC3CCC21
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COCOCcccOC))ccc6CCNC%11cc%15cOCOc5cc9))))))))))C))))))OC
Heavy Atom Count 29.0
Classyfire Class Rhoeadine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCNC1C3CCC4OCOC4C3COC21
Isotope Atom Count 0.0
Molecular Complexity 578.0
Database Name hmdb_chem_all;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 11,16,17-trimethoxy-22-methyl-6,8,12-trioxa-22-azapentacyclo[11.9.0.02,10.05,9.014,19]docosa-2(10),3,5(9),14,16,18-hexaene
Class Rhoeadine alkaloids
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.5
Superclass Alkaloids and derivatives
Gsk 4 400 Rule True
Molecular Formula C22H25NO6
Scaffold Graph Node Bond Level c1ccc2c(c1)CCNC1c3ccc4c(c3COC21)OCO4
Inchi Key STJFYCWYHROASW-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
State Solid
Synonyms N-Methylpapaverrubine b, O,N-Dimethylpapaverrubine D, O,N-Dimethylporphyroxine, Oreodine, glaudine
Esol Class Moderately soluble
Functional Groups CN(C)C, c1cOCO1, cC(OC)OC, cOC
Compound Name Glaudine
Kingdom Organic compounds
Exact Mass 399.168
Formal Charge 0.0
Monoisotopic Mass 399.168
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 399.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H25NO6/c1-23-8-7-12-9-16(24-2)17(25-3)10-14(12)20-19(23)13-5-6-15-21(28-11-27-15)18(13)22(26-4)29-20/h5-6,9-10,19-20,22H,7-8,11H2,1-4H3
Smiles CN1CCC2=CC(=C(C=C2C3C1C4=C(C(O3)OC)C5=C(C=C4)OCO5)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Rhoeadine alkaloids
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Papaver Rhoeas (Plant) Rel Props:Reference:ISBN:9788185042053
  • 2. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729