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[(7aS)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate

PubChem CID: 6328195

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Compound Synonyms [(7aS)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 70.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CCCC2C1
Np Classifier Class Pyrrolizidine alkaloids
Deep Smiles CC[C@]C=O)OCC=CCN[C@H]5CCC5)))))))))))[C@H]O)C))O))C
Heavy Atom Count 20.0
Scaffold Graph Node Level C1CC2CCCN2C1
Isotope Atom Count 0.0
Molecular Complexity 407.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name [(8S)-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.5
Gsk 4 400 Rule True
Molecular Formula C15H25NO4
Scaffold Graph Node Bond Level C1=CC2CCCN2C1
Prediction Swissadme 1.0
Inchi Key DRVWTOSBCBKXOR-OSAQELSMSA-N
Silicos It Class Soluble
Fcsp3 0.8
Rotatable Bond Count 6.0
Synonyms coromandalinine
Esol Class Very soluble
Functional Groups CC=C(C)C, CN(C)C, CO, COC(C)=O
Compound Name [(7aS)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2R)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate
Prediction Hob Swissadme 1.0
Exact Mass 283.178
Formal Charge 0.0
Monoisotopic Mass 283.178
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 283.36
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.5473311999999995
Inchi InChI=1S/C15H25NO4/c1-10(2)15(19,11(3)17)14(18)20-9-12-6-8-16-7-4-5-13(12)16/h6,10-11,13,17,19H,4-5,7-9H2,1-3H3/t11-,13+,15-/m1/s1
Smiles C[C@H]([C@](C(C)C)(C(=O)OCC1=CCN2[C@H]1CCC2)O)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids