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6-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one

PubChem CID: 6325047

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Compound Synonyms 6-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one, 13255-08-8, 3,3-Dimethyl-6-methoxy-3H-pyrano[2,3-c]acridine-7(12H)-one, N-desmethylacronycine, des-N-methylacronycine, CHEMBL454827, NEYQKEUFRBPEJP-UHFFFAOYSA-N, 6-methoxy-3,3-dimethyl-3,12-dihydro-7h-pyrano[2,3-c]acridin-7-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 47.6
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CC2C3CCCCC3CCC12
Np Classifier Class Acridone alkaloids
Deep Smiles COcccOCC)C)C=Cc6cc%10c=O)cc[nH]6)cccc6
Heavy Atom Count 23.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level OC1C2CCCCC2NC2C3CCCOC3CCC12
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 515.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 6-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.5
Gsk 4 400 Rule True
Molecular Formula C19H17NO3
Scaffold Graph Node Bond Level O=c1c2ccccc2[nH]c2c3c(ccc12)OCC=C3
Prediction Swissadme 0.0
Inchi Key NEYQKEUFRBPEJP-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.2105263157894736
Logs -4.16
Rotatable Bond Count 1.0
Logd 3.312
Synonyms de-n-methyl-acronycine, de-n-methylacronycine, des-n-methylacronycine
Esol Class Moderately soluble
Functional Groups c=O, cC=CC, cOC, c[nH]c
Compound Name 6-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
Prediction Hob Swissadme 0.0
Exact Mass 307.121
Formal Charge 0.0
Monoisotopic Mass 307.121
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 307.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.336698582608697
Inchi InChI=1S/C19H17NO3/c1-19(2)9-8-12-14(23-19)10-15(22-3)16-17(12)20-13-7-5-4-6-11(13)18(16)21/h4-10H,1-3H3,(H,20,21)
Smiles CC1(C=CC2=C3C(=C(C=C2O1)OC)C(=O)C4=CC=CC=C4N3)C
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Artemisia Capillaris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Atalantia Buxifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Glycosmis Mauritiana (Plant) Rel Props:Reference:ISBN:9788185042145
  • 4. Outgoing r'ship FOUND_IN to/from Glycosmis Pentaphylla (Plant) Rel Props:Reference:ISBN:9788172360818
  • 5. Outgoing r'ship FOUND_IN to/from Murraya Paniculata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all