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Zizyphine A

PubChem CID: 6324833

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Compound Synonyms Zizyphine A, 51059-42-8, DTXSID60422522, (2S,3S)-2-(dimethylamino)-N-[(2S,3S)-1-[(3S,7S,13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo[16.2.2.03,7.09,13]docosa-1(20),16,18,21-tetraen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-methylpentanamide, zizyphine-A, (2S,3S)-2-(Dimethylamino)-N-((2S,3S)-1-((3R,7S,13S,16Z)-14-hydroxy-19-methoxy-8-oxo-2-oxa-6,9,15-triazatetracyclo(16.2.2.0,.0,)docosa-1(20),14,16,18,21-pentaen-6-yl)-3-methyl-1-oxopentan-2-yl)-3-methylpentanimidate, (2S,3S)-2-(dimethylamino)-N-((2S,3S)-1-((3S,7S,13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo(16.2.2.03,7.09,13)docosa-1(20),16,18,21-tetraen-6-yl)-3-methyl-1-oxopentan-2-yl)-3-methylpentanamide, (2S,3S)-2-(Dimethylamino)-N-[(2S,3S)-1-[(3R,7S,13S,16Z)-14-hydroxy-19-methoxy-8-oxo-2-oxa-6,9,15-triazatetracyclo[16.2.2.0,.0,]docosa-1(20),14,16,18,21-pentaen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-methylpentanimidate, CHEBI:10121, DTXCID80373365, Q27108592
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 121.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2CCC(CC2)CC2CCCC2C(C)C2CCCC12
Np Classifier Class Ansa peptide alkaloids
Deep Smiles CC[C@@H][C@@H]C=O)NCC[C@H][C@H]5C=O)NCCC[C@H]5C=O)N/C=CccccO%17)cc6OC))))))))))))))))))))))))NC=O)[C@H][C@H]CC))C))NC)C))))))C
Heavy Atom Count 44.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC1NCCC2CCC(CC2)OC2CCNC2C(O)N2CCCC12
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 1070.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (2S,3S)-2-(dimethylamino)-N-[(2S,3S)-1-[(3S,7S,13S,16Z)-19-methoxy-8,14-dioxo-2-oxa-6,9,15-triazatetracyclo[16.2.2.03,7.09,13]docosa-1(20),16,18,21-tetraen-6-yl]-3-methyl-1-oxopentan-2-yl]-3-methylpentanamide
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 4.0
Gsk 4 400 Rule False
Molecular Formula C33H49N5O6
Scaffold Graph Node Bond Level O=C1NC=Cc2ccc(cc2)OC2CCNC2C(=O)N2CCCC12
Prediction Swissadme 0.0
Inchi Key NXCUAFMNFVTKHA-YEEQOOFQSA-N
Silicos It Class Moderately soluble
Fcsp3 0.6363636363636364
Logs -4.087
Rotatable Bond Count 9.0
Logd 3.059
Synonyms zizyphine a
Esol Class Moderately soluble
Functional Groups CN(C)C, CN(C)C(C)=O, CNC(C)=O, c/C=CNC(C)=O, cOC
Compound Name Zizyphine A
Prediction Hob Swissadme 0.0
Exact Mass 611.368
Formal Charge 0.0
Monoisotopic Mass 611.368
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 611.8
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -6.12316989090909
Inchi InChI=1S/C33H49N5O6/c1-8-20(3)27(35-31(40)28(36(5)6)21(4)9-2)32(41)38-18-15-25-29(38)33(42)37-17-10-11-24(37)30(39)34-16-14-22-12-13-23(44-25)19-26(22)43-7/h12-14,16,19-21,24-25,27-29H,8-11,15,17-18H2,1-7H3,(H,34,39)(H,35,40)/b16-14-/t20-,21-,24-,25-,27-,28-,29-/m0/s1
Smiles CC[C@H](C)[C@@H](C(=O)N1CC[C@H]2[C@H]1C(=O)N3CCC[C@H]3C(=O)N/C=C\C4=C(C=C(O2)C=C4)OC)NC(=O)[C@H]([C@@H](C)CC)N(C)C
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids, Amino acids and Peptides
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Peptide alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Ziziphus Jujuba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Ziziphus Oenopolia (Plant) Rel Props:Reference:ISBN:9788185042114