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(+/-)-Karachine

PubChem CID: 630739

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Compound Synonyms (.+/-.)-Karachine, CFSSZVBJSHOACV-UHFFFAOYSA-N
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 57.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CC3C4CCCCC4C2C2(C1)C1CC4CCCC4CC1CCC32
Np Classifier Class Isoquinoline alkaloids, Protoberberine alkaloids
Deep Smiles COcccccc6OC)))CCCC6CN6CCcc6ccOCOc5c9))))))))))))CC=O)C6)))))C
Heavy Atom Count 32.0
Classyfire Class Protoberberine alkaloids and derivatives
Scaffold Graph Node Level OC1CC2CC3C4CCCCC4C2C2(C1)C1CC4OCOC4CC1CCN32
Isotope Atom Count 0.0
Molecular Complexity 805.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 23,24-dimethoxy-18-methyl-8,10-dioxa-2-azaheptacyclo[16.7.1.02,14.05,13.07,11.014,19.020,25]hexacosa-5,7(11),12,20(25),21,23-hexaen-16-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.0
Gsk 4 400 Rule False
Molecular Formula C26H27NO5
Scaffold Graph Node Bond Level O=C1CC2CC3c4ccccc4C2C2(C1)c1cc4c(cc1CCN32)OCO4
Prediction Swissadme 1.0
Inchi Key CFSSZVBJSHOACV-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5
Logs -4.156
Rotatable Bond Count 2.0
Logd 3.21
Synonyms karachine
Esol Class Moderately soluble
Functional Groups CC(C)=O, CN(C)C, c1cOCO1, cOC
Compound Name (+/-)-Karachine
Prediction Hob Swissadme 1.0
Exact Mass 433.189
Formal Charge 0.0
Monoisotopic Mass 433.189
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 433.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.563224800000001
Inchi InChI=1S/C26H27NO5/c1-25-10-15(28)11-26-17-9-21-20(31-13-32-21)8-14(17)6-7-27(26)18(12-25)22-16(24(25)26)4-5-19(29-2)23(22)30-3/h4-5,8-9,18,24H,6-7,10-13H2,1-3H3
Smiles CC12CC3C4=C(C1C5(N3CCC6=CC7=C(C=C65)OCO7)CC(=O)C2)C=CC(=C4OC)OC
Nring 8.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids