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Isotiliarine

PubChem CID: 630659

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Compound Synonyms Isotiliarine, Nortiliacorine A, CHEMBL5173840, DOUULZLWVARYRD-UHFFFAOYSA-N, Rodiasine, 6',7-didemethoxy-2'-demethyl-6',7-epoxy-, (1.alpha.,1'.alpha.)-, 2H,16H-22,26-Epoxy-1,24-etheno-6,10:11,15-dimethenopyrido[2',3':17,18]oxacycloeicosino[2,3,4-ij]isoquinolin-9-ol,3,4,4a,5,16a,17,18,19- octahydro-12,21-dimethoxy-17-methyl-,(4aS,16aR)-
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 72.4
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC(C1)C1CCCC(C1)CC1CCCC3CCC4CC5CC6CCCC(C2)C6CC5CC4C31
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COcccCCNCc6cc%10OcccCCNCc6cc%10O%14))))Cccc-cccC%20)ccc6OC))))))))cO)cc6)))))))))))))))))))C
Heavy Atom Count 42.0
Scaffold Graph Node Level C1CC2CC(C1)C1CCCC(C1)CC1NCCC3CCC4OC5CC6CCNC(C2)C6CC5OC4C31
Isotope Atom Count 0.0
Molecular Complexity 952.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 16,27-dimethoxy-22-methyl-29,31-dioxa-7,22-diazaoctacyclo[19.9.3.14,30.110,14.115,19.03,8.025,33.028,32]hexatriaconta-1(30),2,4(34),10(36),11,13,15,17,19(35),25,27,32-dodecaen-13-ol
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 5.6
Gsk 4 400 Rule False
Molecular Formula C35H34N2O5
Scaffold Graph Node Bond Level c1cc2cc(c1)-c1cccc(c1)CC1NCCc3ccc4c(c31)Oc1cc3c(cc1O4)CCNC3C2
Inchi Key DOUULZLWVARYRD-UHFFFAOYSA-N
Silicos It Class Insoluble
Rotatable Bond Count 2.0
Synonyms nortiliacorine a
Esol Class Poorly soluble
Functional Groups CN(C)C, CNC, cO, cOC, cOc
Compound Name Isotiliarine
Exact Mass 562.247
Formal Charge 0.0
Monoisotopic Mass 562.247
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 562.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Inchi InChI=1S/C35H34N2O5/c1-37-11-9-22-17-32(40-3)34-35-33(22)27(37)15-20-5-7-29(39-2)25(13-20)24-12-19(4-6-28(24)38)14-26-23-18-31(42-35)30(41-34)16-21(23)8-10-36-26/h4-7,12-13,16-18,26-27,36,38H,8-11,14-15H2,1-3H3
Smiles CN1CCC2=CC(=C3C4=C2C1CC5=CC(=C(C=C5)OC)C6=C(C=CC(=C6)CC7C8=CC(=C(O3)C=C8CCN7)O4)O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Tiliacora Racemosa (Plant) Rel Props:Reference:ISBN:9788185042084
  • 2. Outgoing r'ship FOUND_IN to/from Tiliacora Triandra (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042138