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Pyrrolo[2,1-b]quinazolin-9(1H)-one, 3-[2-(dimethylamino)phenyl]-2,3-dihydro-

PubChem CID: 627712

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Compound Synonyms Vasicolinone, Vasicolinon, 33903-15-0, ADHMTMIOMYKZHH-UHFFFAOYSA-N, Pyrrolo[2,1-b]quinazolin-9(1H)-one, 3-[2-(dimethylamino)phenyl]-2,3-dihydro-, DB-262065, 3-[2-(Dimethylamino)phenyl ]-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one, 3-[2-(Dimethylamino)phenyl]-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 35.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CC2C(C3CCCCC3)CCC12
Np Classifier Class Quinazoline alkaloids
Deep Smiles CNcccccc6CCCnc5ncccccc6c%10=O))))))))))))))))))))C
Heavy Atom Count 23.0
Classyfire Class Diazanaphthalenes
Scaffold Graph Node Level OC1C2CCCCC2NC2C(C3CCCCC3)CCN12
Classyfire Subclass Benzodiazines
Isotope Atom Count 0.0
Molecular Complexity 501.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 3-[2-(dimethylamino)phenyl]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C19H19N3O
Scaffold Graph Node Bond Level O=c1c2ccccc2nc2n1CCC2c1ccccc1
Prediction Swissadme 1.0
Inchi Key ADHMTMIOMYKZHH-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.2631578947368421
Logs -3.401
Rotatable Bond Count 2.0
Logd 2.69
Synonyms vasicolinone
Esol Class Soluble
Functional Groups c=O, cN(C)C, cn(c)C, cnc
Compound Name Pyrrolo[2,1-b]quinazolin-9(1H)-one, 3-[2-(dimethylamino)phenyl]-2,3-dihydro-
Prediction Hob Swissadme 1.0
Exact Mass 305.153
Formal Charge 0.0
Monoisotopic Mass 305.153
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 305.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.724344808695652
Inchi InChI=1S/C19H19N3O/c1-21(2)17-10-6-4-7-13(17)14-11-12-22-18(14)20-16-9-5-3-8-15(16)19(22)23/h3-10,14H,11-12H2,1-2H3
Smiles CN(C)C1=CC=CC=C1C2CCN3C2=NC4=CC=CC=C4C3=O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Adhatoda Vasica (Plant) Rel Props:Source_db:npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Justicia Adhatoda (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all