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Cycloheximide

PubChem CID: 6197

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Compound Synonyms cycloheximide, 66-81-9, ACTIDIONE, Cicloheximide, NARAMYCIN A, Kaken, Actidion, Actidone, Hizarocin, Neocycloheximide, Acti-Aid, Actispray, Naramycin, Actidione PM, Cicloheximida, Cycloheximid, Acti-Dione, Actidione BR, Actidione TGF, Cycloheximide [USAN], NSC-185, Aktidion [Czech], Cicloheximidum, Zykloheximid, Aktidion, NSC 185, Caswell No. 270A, U-4527, Acti-dione BR, 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione, C15H23NO4, Cicloheximidum [INN-Latin], Cicloheximida [INN-Spanish], Cicloheximide [INN], CCRIS 937, Cyclohemimide, Cyclohexamide, CBC 500046, DTXSID6024882, HSDB 1552, TCMDC-125838, Cycloheximide [BSI:ISO], Acti-dione PM, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, Acti-dione TGF, EINECS 200-636-0, NM-MCD 80, U 4527, EPA Pesticide Chemical Code 043401, 3-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, BRN 0088868, NSC185, Cicloheximide (INN), CHEBI:27641, GNF-PF-5118, Cycloheximide (USAN), AI3-15541, MFCD00082346, UNII-98600C0908, CYCLOHEXIMIDE [MI], 3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, CYCLOHEXIMIDE [ISO], beta-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, CYCLOHEXIMIDE [HSDB], 3-(2R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethylglutarimide, CICLOHEXIMIDE [MART.], FT 3422-2, CHEMBL123292, DTXCID204882, (1S-(1alpha(S*),3alpha,5beta))-4-(2-(3,5-Dimethyl-2-oxo-cyclohexyl))-2-hydroxyethyl-2,6-piperidinedione, 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-, TZA, 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, 5-21-13-00434 (Beilstein Handbook Reference), 4-((2R)-2-((1S,3S,5S)-(3,5-Dimethyl-2-oxocyclohexyl))-2-hydroxyethyl)piperidine-2,6-dione, 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione, 98600C0908, CX, Cicloheximidum (INN-Latin), 2,6-Piperidinedione, 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-, 4-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)piperidine-2,6-dione, Cicloheximida (INN-Spanish), CHX, CICLOHEXIMIDE (MART.), .beta.-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, 2,6-Piperidinedione, 4-((2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, 2,6-PIPERIDINEDIONE, 4-(2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-, (1S-(1.ALPHA.(S*),3.ALPHA.,5.BETA.))-, 2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-, 4-((2R)-2-((1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-2,6-PIPERIDINEDIONE, 4-((2R)-2-((1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)PIPERIDINE-2,6-DIONE, SMR000686067, Actidione, Naramycin A, CHX, SR-01000597484, SR-05000001596, ActiAid, .beta.-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 3-[(R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]glutarimide, CAS-66-81-9, NCGC00024910-01, 2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1alpha(S*),3alpha,5beta]]-, Prestwick_976, Spectrum_001344, Prestwick0_000790, Prestwick1_000790, Prestwick2_000790, Prestwick3_000790, Spectrum2_000900, Spectrum3_001510, Spectrum4_000914, Spectrum5_001635, cid_6197, Pesticide Code: 043401, SCHEMBL26617, BSPBio_000900, BSPBio_003159, KBioGR_001408, KBioSS_001824, ksc-8-190, MLS001055333, MLS002154001, DivK1c_000050, SPECTRUM1502112, SPBio_000720, SPBio_002839, 4-[2-(3,6-piperidinedione, BPBio1_000990, GTPL5433, HMS500C12, KBio1_000050, KBio2_001824, KBio2_004392, KBio2_006960, KBio3_002659, 3-((2R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 3-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]glutarimide, NINDS_000050, GLXC-10322, HMS1570M22, HMS1921L04, HMS2092D10, HMS2097M22, HMS3714M22, KUC105858N, Pharmakon1600-01502112, Cycloheximide, Streptomyces griseus, 4-((2R)-2-((1S,3S,5S)-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione, Tox21_113580, Tox21_201158, Tox21_303652, BDBM50080528, CCG-39902, Cycloheximide, >=93.0% (HPLC), HB2904, NSC758187, 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione, AKOS024282670, Tox21_113580_1, ACTI-DIONE-PM(-RZ,-BR,&-S), CS-4985, NSC-758187, IDI1_000050, NCGC00017363-05, NCGC00017363-06, NCGC00017363-07, NCGC00017363-08, NCGC00017363-10, NCGC00017363-18, NCGC00024910-02, NCGC00024910-03, NCGC00024910-04, NCGC00024910-05, NCGC00024910-06, NCGC00169964-05, NCGC00257430-01, NCGC00258710-01, 4-[(2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]azaperhydro ine-2,6-dione, AC-35130, AC172520, AS-14624, BP-12396, HY-12320, NCI60_001540, SBI-0051732.P002, WLN: T6VMVTJ E1YQ- BL6VTJ D1 F1, Cycloheximide 100 microg/mL in Acetonitrile, NS00004971, U4527, Cycloheximide, from microbial, >=94% (TLC), C06685, D03625, M01527, AB00052279_08, Cycloheximide, PESTANAL(R), analytical standard, Cycloheximide, Biotechnology Performance Certified, Q412895, SR-01000597484-1, SR-01000597484-4, SR-05000001596-1, SR-05000001596-3, SR-05000001596-4, BRD-K36055864-001-05-1, BRD-K36055864-001-07-7, BRD-K36055864-001-09-3, BRD-K36055864-001-16-8, BRD-K36055864-001-19-2, BRD-K36055864-001-20-0, Cycloheximide - Antibiotic for Culture Media Use Only, 3(2(3,5Dimethyl2oxocyclohexyl)2hydroxyethyl)glutarimide, beta(2(3,5Dimethyl2oxocyclohexyl)2hydroxyethyl)glutarimide, Glutarimide, 3(2(3,5dimethyl2oxocyclohexyl)2hydroxyethyl), 3(2((1S,3S,5S)3,5Dimethyl2oxocyclohexyl)2hydroxyethyl)glutarimide, 3(2R)2((1S,3S,5S)3,5Dimethyl2oxocyclohexyl)2hydroxyethylglutarimide, 4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl) 2,6-piperidinedione, 2,6-Piperidinedione, 4-[2-(3,5-dimethyl-2-oxocyclohex-1-yl)-2-hydroxy]ethyl-, 4((2R)2((1S,3S,5S)(3,5Dimethyl2oxocyclohexyl))2hydroxyethyl)piperidine2,6dione, (1S(1alpha(S*),3alpha,5beta))4(2(3,5Dimethyl2oxocyclohexyl))2hydroxyethyl2,6piperidinedione, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione, 1154-57-0, 2, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-, 2,6-PIPERIDINEDIONE, 4-(2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-(1S-(1 ALPHA(S*), 3 ALPHA, 5 BETA))-, 2,6Piperidinedione, 4(2(3,5dimethyl2oxocyclohexyl)2hydroxyethyl), (1S(1alpha(S*),3alpha,5beta)), 4-[(2R)-2-[(1S,3S,5R)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione, 4630-75-5
Topological Polar Surface Area 83.5
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 20.0
Isotope Atom Count 0.0
Molecular Complexity 404.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id P62942, Q02790, Q9NWM8, Q00688, Q13526, Q9Y237, n.a., Q99814, P49841, P51151, Q16637, P51450, P00352, P15917, O15118, P04637, P08684, Q16236, P0CX82, Q96QE3, P19793, P10275, P83916, Q96RI1, P10828, P37231, P03372, Q03181, P84022, P11473, P07900, P04150, Q8IL32, O75496, P19838, Q99700, P43220, Q9R1A7, P10145, P51449, O42275, P81908, Q9NUW8, O75874, Q13148, P37840, Q9NPD5, Q9Y6L6, O94782, P06492, P27695, P24468, O97467, P11166, O61059, P0DTD1, P60842, P05412
Iupac Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
Prediction Hob 1.0
Target Id NPT4166, NPT4371, NPT5457, NPT5458, NPT5459, NPT537, NPT93, NPT94, NPT538, NPT539, NPT109, NPT918, NPT3133, NPT942, NPT3820
Xlogp 0.5
Molecular Formula C15H23NO4
Prediction Swissadme 1.0
Inchi Key YPHMISFOHDHNIV-FSZOTQKASA-N
Fcsp3 0.8
Logs -1.595
Rotatable Bond Count 3.0
Logd -0.597
Compound Name Cycloheximide
Prediction Hob Swissadme 1.0
Exact Mass 281.163
Formal Charge 0.0
Monoisotopic Mass 281.163
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 281.35
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Esol -1.9407823999999998
Inchi InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
Smiles C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
Nring 2.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Aglaia Gigantea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Andropogon Nardus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Caesalpinia Pulcherrima (Plant) Rel Props:Source_db:npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Ceiba Pentandra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Clibadium Pentaneuron (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Croton Californicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Croton Sparsiflorus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Culcitium Canescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Dendrobium Rotundatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Eriostemon Fitzgeraldii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Espeletia Marcana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Malva Crispa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Neoalsomitra Integrifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Nolina Erumpens (Plant) Rel Props:Source_db:cmaup_ingredients
  • 15. Outgoing r'ship FOUND_IN to/from Petasites Niveus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 16. Outgoing r'ship FOUND_IN to/from Picrorhiza Kurrooa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Piptolepis Leptospermoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Ratibida Latipalearis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Solanum Toxicarium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Streptocaulon Juventas (Plant) Rel Props:Source_db:cmaup_ingredients
  • 21. Outgoing r'ship FOUND_IN to/from Toxicodendron Succedaneum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Weddellina Squamulosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all