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Strophanthidin

PubChem CID: 6185

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Compound Synonyms strophanthidin, Convallatoxigenin, 66-28-4, Strophanthidine, Corchsularin, k-Strophanthidin, Corchorgenin, Erysimupicrone, Corchorin, Corchoside A aglycon, Strophanthidin K, Erysimupikron, Apocymarin, Apocynamarin, k-Strophanthidine, Cymarigenin, Cynotoxin, 5beta-Hydroxy-19-oxodigitoxigenin, Antibiotic XS-89, NSC-86078, Strophantidine, CHEBI:38178, 3beta,5,14-Trihydroxy-19-oxo-5beta-card-20(22)-enolide, XS-89, 5-beta-Hydroxy-19-oxodigitoxigenin, EINECS 200-626-6, NSC 86078, BRN 0097859, (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde, STROPHANTHIN-K, W5O632DN33, NSC86078, STROPHANTHIDIN [MI], MLS002153969, 3-beta,5,14-Trioxy-19-oxo-digen-(20:22)-olid [German], STROPHANTHIN-K [WHO-DD], 19-Oxo-cardogenen-(20:22)-triol-(3-beta,5,14) [German], 3-beta,5,14-Trihydroxy-19-oxo-5-beta-card-20(22)-enolide, 3-beta,5,14-Trioxy-19-oxo-carden-(20:22)-olid [German], (3beta,5beta)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide, DTXSID00903966, Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-, 5-18-05-00126 (Beilstein Handbook Reference), 3-beta,5,14-Trioxy-19-oxo-carden-(20:22)-olid, 3-beta,5,14-Trioxy-19-oxo-digen-(20:22)-olid, 5.beta.-Hydroxy-19-oxodigitoxigenin, 19-OXO-CARDOGENEN-(20:22)-TRIOL-(3-beta,5,14), 5beta-Card-20(22)-enolide, 3beta,5,14-trihydroxy-19-oxo-, (3.beta.,5.beta.)-3,5,14-Trihydroxy-19-oxocard-20(22)-enolide, 5-beta-CARD-20(22)-ENOLIDE, 3-beta,5,14-TRIHYDROXY-19-OXO-, Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3-beta,5-beta)-, Cymarigenen, 3beta,5,14-Trihydroxy-19-oxo-5beta,20(22)-cardenolide, CARD-20(22)-ENOLIDE, 3,5,14-TRIHYDROXY-19-OXO-, 5.beta.-Card-20(22)-enolide, 3.beta.,5,14-trihydroxy-19-oxo-, UNII-W5O632DN33, (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthrene-10-carbaldehyde, Prestwick_117, kappa-Strophanthidine, MFCD00046266, Corchoside A, aglycon, Prestwick0_000710, Prestwick1_000710, Prestwick2_000710, Prestwick3_000710, Strophanthidin (Standard), 19-Oxo-cardogenen-(20:22)-triol-(3-.beta.,5,14), 3-.beta.,5,14-Trioxy-19-oxo-carden-(20:22)-olid, 3-.beta.,5,14-Trioxy-19-oxo-digen-(20:22)-olid, BSPBio_000899, SCHEMBL240582, SPBio_002820, 3.beta.,5,14-Trihydroxy-19-oxo-5.beta.-card-20(22)-enolide, BPBio1_000989, CHEMBL111743, Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3.beta.,5.beta.)-, ODJLBQGVINUMMR-HZXDTFASSA-N, DTXCID001331905, HMS1570M21, HMS2097M21, HMS2233O14, BDBM50255120, LMST01120005, AKOS024280415, HY-114252R, NCGC00142399-02, (1S,2S,5S,7S,11S,10R,14R,15R)-5,7,11-trihydroxy-15-methyl-14-(5-oxo(3-2-hydrof uryl))tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadecane-2-carbaldehyde, 1397-98-4, NCI60_041903, SMR001233308, HY-114252, CS-0080731, NS00010436, C19988, F82324, SR-01000838893, Q1718068, SR-01000838893-2, BRD-K84595254-001-03-0, BRD-K84595254-001-10-5, 5.beta.-Card-20(22)-enolide,5,14-trihydroxy-19-oxo-, WLN: L E5 B666TJ AVH E1 IQ MQ OQ F- DT5OV EHJ, 3.beta.,14-Trihydroxy-19-oxo-5.beta.-card-20(22)-enolide, 5beta-Card-20(22)-enolide, 3beta,5,14-trihydroxy-19-oxo-(8CI), Card-20(22)-enolide,5,14-trihydroxy-19-oxo-, (3.beta.,5.beta.)-, Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3-beta,5-beta)-(9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 104.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C2CCC3C2CCC2C4CCCCC4CCC23)C1
Np Classifier Class Cardenolides
Deep Smiles O=C[C@]CC[C@@H]C[C@@]6O)CC[C@@H][C@@H]%10CC[C@][C@]6O)CC[C@@H]5C=CC=O)OC5)))))))))C))))))))))O
Heavy Atom Count 29.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 777.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id Q99814, n.a., Q03164, P51151, O15118, P04637, Q16236, Q96QE3, P83916, P84022, P16473, O75496, Q99700, P43220, P38398, P11308, Q9NUW8, Q06710, O75874, Q9Y6L6, Q9NPD5, P07340
Iupac Name (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Target Id NPT537, NPT538, NPT539, NPT1283
Xlogp 0.6
Gsk 4 400 Rule False
Molecular Formula C23H32O6
Scaffold Graph Node Bond Level O=C1C=C(C2CCC3C2CCC2C4CCCCC4CCC23)CO1
Prediction Swissadme 1.0
Inchi Key ODJLBQGVINUMMR-HZXDTFASSA-N
Silicos It Class Soluble
Fcsp3 0.8260869565217391
Logs -3.073
Rotatable Bond Count 2.0
Logd 1.168
Synonyms corchorin, corchorogenin, corchsularin, strophanthidin
Esol Class Soluble
Functional Groups CC1=CC(=O)OC1, CC=O, CO
Compound Name Strophanthidin
Prediction Hob Swissadme 1.0
Exact Mass 404.22
Formal Charge 0.0
Monoisotopic Mass 404.22
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 404.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.619118600000001
Inchi InChI=1S/C23H32O6/c1-20-6-3-17-18(4-8-22(27)11-15(25)2-7-21(17,22)13-24)23(20,28)9-5-16(20)14-10-19(26)29-12-14/h10,13,15-18,25,27-28H,2-9,11-12H2,1H3/t15-,16+,17-,18+,20+,21-,22-,23-/m0/s1
Smiles C[C@]12CC[C@H]3[C@H]([C@]1(CC[C@@H]2C4=CC(=O)OC4)O)CC[C@]5([C@@]3(CC[C@@H](C5)O)C=O)O
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

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