Progesterone
PubChem CID: 5994
Connections displayed (default: 10).
Loading graph...
| Compound Synonyms | progesterone, 57-83-0, Pregn-4-ene-3,20-dione, Agolutin, Crinone, 4-Pregnene-3,20-dione, Prometrium, Utrogestan, Progestin, Luteol, Gestormone, Glanducorpin, Pregnenedione, Progesterol, Progesteronum, Progestone, Progestron, Syngesterone, Corlutin, Hormoflaveine, Lutociclina, Methylpregnone, Progestasert, Progestosol, Progestronol, Syngestrets, Corporin, Cyclogest, Flavolutan, Fologenon, Gestone, Gestron, Gynlutin, Gynolutone, Hormoluton, Lingusorbs, Lucorteum, Luteodyn, Luteogan, Luteopur, Luteosan, Luteostab, Luteovis, Lutidon, Lutocylin, Lutoform, Membrettes, Nalutron, Piaponon, Primolut, Progekan, Prolets, Protormone, Syntolutan, Lutren, Lucorteum Sol, Bio-luton, Lutocyclin M, Luteocrin normale, Corlutina, Corluvite, Gesterol, Luteinique, Lutocyclin, Lutromone, Prochieve, Prolidon, Proluton, Prolutone, Lutogyl, Lutex, Lutin, 17alpha-Progesterone, Lipo-Lutin, Synovex S, Gynoluton, Projestaject, Percutacrine Luteinique, Gesterol 100, Akrolutin, Gesterol 50, Pregnene-3,20-dione, Cyclogesterin, Endometrin, Progesteron, Prolutin, (S)-Progesterone, 3,20-Pregnene-4, Gelbkoerperhormon, Colprosterone, Progestogel, Progeston, Crinone progesterone gel, Progesterona, Gestiron, Lugesteron, Progestol, Vitarrine, Luteol (VAN), NSC-9704, Lutocuclin M, (S)-4-Pregnene-3,20-dione, Delta(4)-pregnene-3,20-dione, (S)-Pregn-4-en-3,20-dione, .beta.-Progesterone, delta(sup 4)-Pregnene-3,20-dione, Percutacrine, Progeffik, Utrogest, Luteum, Progesteronum [INN-Latin], Progesterona [INN-Spanish], CCRIS 533, HSDB 3389, AI3-51682, Prontogest, Lipolutin, Lutogynon, Estima, Progesterone, micronized, 17.alpha.-Progesterone, 6alpha-Methylpregn-4-en-17alpha-ol-3,20-dione, Progesterone [Progestins], NSC 9704, Prometrium (TN), EINECS 200-350-6, Pregn-4-en-3,20-dione, UNII-4G7DS2Q64Y, NSC 64377, NSC-64377, Crinone (TN), Pregn-4-ene-3,20-dione, 17alpha-hydroxy-6alpha-methyl-, MILPROSA, DTXSID3022370, CHEBI:17026, .delta.4-Pregnene-3,20-dione, 17alpha-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione, Progesterone (Standard), delta(Sup4)-pregnene-3,20-dione, component of Cyclogesterin, MFCD00003658, U 3672, 4-Pregnen-3,20-dione, .delta.(sup4)-Pregnene-3,20-dione, CHEMBL103, D4-Pregnene-3,20-dione, (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, MLS000028517, 4G7DS2Q64Y, DTXCID902370, NSC9704, EC 200-350-6, Progesterone [USP:INN:BAN:JAN], BIJUVA COMPONENT PROGESTERONE, NSC64377, NCGC00015785-04, SMR000058345, Progesteronum (INN-Latin), Progesterona (INN-Spanish), PROGESTERONE (MART.), PROGESTERONE [MART.], PROGESTERONE (USP-RS), PROGESTERONE [USP-RS], 6.alpha.-Methylpregn-4-en-17.alpha.-ol-3,20-dione, 17.alpha.-Hydroxy-6.alpha.-methylpregn-4-ene-3,20-dione, Progestan, PROGESTERONE (EP MONOGRAPH), Progesterone (USP:INN:BAN:JAN), PROGESTERONE [EP MONOGRAPH], Pregn-4-ene-3,20-dione, 17.alpha.-hydroxy-6.alpha.-methyl-, PROGESTERONE (USP MONOGRAPH), PROGESTERONE [USP MONOGRAPH], SMR000653542, Natural Progesterone, Progesterone (Prometrium), WLN: L E5 B666 OV MUTJ A1 E1 FV1, SR-01000000088, SR-01000076054, Pregn-4-ene-3, 17.alpha.-hydroxy-6.alpha.-methyl-, BHR-100, Duraprogen, Progestrel, Lutinus, Gelbkorperhormon, Progesto-Life, beta-Progesterone, 1dbb, 17a-Progesterone, Progesterone Combo, CAS-57-83-0, Progesterone1538, racemic progesterone, Prestwick_411, Progesterone Phenolic, CIDR, mpp22, 2aa6, 4bb2, Opera_ID_292, P25 Progesterone Cream, P50 Progesterone Cream, P75 Progesterone Cream, Progesterone, >=99%, Prestwick0_000477, Prestwick1_000477, Prestwick2_000477, Prestwick3_000477, Spectrum5_002053, PROGESTERONE [MI], Cyclogesterin (Salt/Mix), PROGESTERONE [INN], PROGESTERONE [JAN], bmse000482, Epitope ID:116051, PROGESTERONE [HSDB], SCHEMBL7671, Ferring Pharmaceuticals Inc., P75 Lav Progesterone Cream, PROGESTERONE [VANDF], BIDD:PXR0094, Lopac0_000895, BSPBio_000614, MLS000758277, MLS001074187, MLS001423982, MLS002222367, BIDD:ER0547, P0130_SIGMA, PROGESTERONE [WHO-DD], PROGESTERONE [WHO-IP], Advanced Formula Progesto-Life, SPBio_002553, .delta.-Pregnene-3,20-dione, BDBM8903, BPBio1_000676, EAZI-BREED CIDR SheepInsert, GTPL2377, Hydroxyprogesterone Caproic acid, EAZI-BREED CIDR CattleInsert, EAZI-BREED CIDR Sheep Insert, HY-N0437R, Progesterone (JP18/USP/INN), BHR-310, EAZI-BREED CIDR Cattle Insert, ETI-411, G03DA04, MSK2223, PROGESTERONE [GREEN BOOK], 1a28, 1h60, HMS1569O16, HMS2051O05, HMS2090J07, HMS2096O16, HMS2230F23, HMS2233P11, HMS3262D12, HMS3713O16, Pregnene, 3,20-dione-delta^4-, PROGESTERONE [ORANGE BOOK], BCP22000, HY-N0437, Tox21_113157, Tox21_201792, Tox21_300307, Tox21_500895, AC-700, CMC_13406, LMST02030159, Progesterone, 1mg/ml in Acetonitrile, PROGESTERONUM [WHO-IP LATIN], s1705, AKOS015894908, Progesterone, 4-Pregnene-3,20-dione, 1ST2223, CCG-100766, CS-1937, DB00396, DR-2011, FD12045, FP27173, LP00895, NC00016, PROGESTERONE COMPONENT OF BIJUVA, SDCCGSBI-0050870.P002, Progesterone 1.0 mg/ml in Acetonitrile, NCGC00022185-03, NCGC00022185-04, NCGC00022185-05, NCGC00022185-06, NCGC00022185-07, NCGC00022185-08, NCGC00022185-09, NCGC00022185-10, NCGC00022185-11, NCGC00022185-12, NCGC00022185-14, NCGC00022185-21, NCGC00090798-01, NCGC00090798-02, NCGC00254120-01, NCGC00259341-01, NCGC00261580-01, (1S,10S,11S,14S,15S,2R)-14-acetyl-2,15-dimethyl-5-oxotetracyclo[8.7.0.0<2,7>.0 <11,15>]heptadec-6-ene, (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one, (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one, AS-12660, CPD000058345, NCI60_042166, FE-999913, CS-0694805, EU-0100895, NS00010899, P0478, (14beta,17alpha)-pregn-4-ene-3,20-dione, Progesterone, meets USP testing specifications, Progesterone, Vetec(TM) reagent grade, 98%, C00410, D00066, P 0130, Q26963, S00293, Progesterone, VETRANAL(TM), analytical standard, SR-01000000088-5, SR-01000000088-6, SR-01000076054-1, SR-01000076054-4, BRD-K64994968-001-03-6, 32104FB6-BF81-4F6E-83C2-024DEEAEB272, Z1501485353, P75 Maxx with Retinol All Natural Progesterone 75 Cream, Pregn-4-ene-3,20-dione, ?4-Pregnene-3,20-dione, Agolutin, Progesterone, British Pharmacopoeia (BP) Reference Standard, Progesterone, powder, BioReagent, suitable for cell culture, Progesterone, European Pharmacopoeia (EP) Reference Standard, Progesterone, gamma-irradiated, BioXtra, suitable for cell culture, Progesterone, United States Pharmacopeia (USP) Reference Standard, Progesterone-Water Soluble, powder, BioReagent, suitable for cell culture, Progesterone for peak identification, European Pharmacopoeia (EP) Reference Standard, Progesterone for system suitability, European Pharmacopoeia (EP) Reference Standard, Progesterone, Pharmaceutical Secondary Standard, Certified Reference Material, (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one, 137940-28-4, 200-350-6, 753497-20-0 |
|---|---|
| Ghose Rule | True |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 34.1 |
| Hydrogen Bond Donor Count | 0.0 |
| Pfizer 3 75 Rule | False |
| Scaffold Graph Level | CC1CCC2C(CCC3C4CCCC4CCC23)C1 |
| Np Classifier Class | Pregnane steroids |
| Deep Smiles | O=CCC[C@]C=C6)CC[C@@H][C@@H]6CC[C@][C@H]6CC[C@@H]5C=O)C))))))C)))))))))C |
| Heavy Atom Count | 23.0 |
| Classyfire Class | Steroids and steroid derivatives |
| Description | Progestational hormone secreted by corpus luteum during menstrual cycleand is also found in the gonads and haemolymph of crustaceans, e.g. Artemia, Euphosia, Homarus, Pandalus and Penaeus spp (CCD). |
| Scaffold Graph Node Level | OC1CCC2C(CCC3C4CCCC4CCC23)C1 |
| Classyfire Subclass | Pregnane steroids |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 589.0 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 6.0 |
| Uniprot Id | P15538, P51857, P05108, P08684, P11712, P33261, P05093, Q16678, P10635, P20815, P04798, P24462, P05177, P10632, P11509, P06401, Q13352, P33527, O95342, P03372, P08183, Q14973, O15245, P08235, O15244, O75751, P14060, P26439, P19099, Q16874, O00264, O15173, Q08AG9, Q13451, Q15185, Q6TZ08, P08686, Q63449, n.a., P08185, P04278, P02768, P10275, P04150, P06536, O35627, P31214, Q9GK37, P19091, P19785, P06186, P15207, P22199, P35610, P07812, Q62986, Q15125, Q99720, P32352, Q92731, Q8TDU6, Q16850, Q9UNQ0, Q92887, P02692, P12104, P56937, P02545, B2RXH2, P51151, Q16637, P02791, P16473, P10636, Q16665, P00352, Q01453, Q194T2, P28482, Q03164, P08482, P40225, Q6W5P4, P51450, Q96QE3, Q16236, P21728, Q96KQ7, Q60492, P11473, P19793, P10828, Q96RI1, O95149, Q12809, Q03181, P37231, O75795, Q690N0, Q9R0W2, O88446, Q99700, P43220, Q9R1A7, P10145, P51449, O94956, Q9NPD5, Q9Y6L6, Q9NUW8, O75874, Q13148, Q03431, P15289, Q8WZA2, Q9R0C9, Q28590, P56373, P0DTD1, P19838 |
| Iupac Name | (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one |
| Prediction Hob | 1.0 |
| Class | Steroids and steroid derivatives |
| Veber Rule | True |
| Classyfire Superclass | Lipids and lipid-like molecules |
| Target Id | NPT542, NPT153, NPT249, NPT541, NPT212, NPT1214, NPT894, NPT296, NPT668, NPT745, NPT1422, NPT5155, NPT483, NPT48, NPT537, NPT93, NPT210, NPT51, NPT211, NPT94, NPT796, NPT282, NPT96, NPT1416, NPT109, NPT713, NPT1540, NPT613, NPT1546, NPT2675 |
| Xlogp | 3.9 |
| Superclass | Lipids and lipid-like molecules |
| Subclass | Pregnane steroids |
| Gsk 4 400 Rule | False |
| Molecular Formula | C21H30O2 |
| Scaffold Graph Node Bond Level | O=C1C=C2CCC3C4CCCC4CCC3C2CC1 |
| Prediction Swissadme | 1.0 |
| Inchi Key | RJKFOVLPORLFTN-LEKSSAKUSA-N |
| Silicos It Class | Moderately soluble |
| Fcsp3 | 0.8095238095238095 |
| Logs | -3.841 |
| Rotatable Bond Count | 1.0 |
| State | Solid |
| Logd | 3.654 |
| Synonyms | (S)-4-Pregnene-3,20-dione, (S)-Pregn-4-en-3,20-dione, (S)-Progesterone, 17alpha-progesterone, 4-Pregnene-3,20-dione, Agolutin, Akrolutin, Corlutin, Glanducorpin, Luteohormone, Nalutron, Progesterone, Progestone, Syngesterone, Utrogestan, Vitarrine, 17alpha-Progesterone, Corpus luteum hormone, Crinone, Delta(4)-Pregnene-3,20-dione, Gelbkoerperhormon, Progesteron, Prometrium, 17a-Progesterone, 17Α-progesterone, Δ(4)-pregnene-3,20-dione, 3,20-Pregnene-4, 4-Pregnen-3,20-dione, beta-Progesterone, Bio-luton, CIDR, Colprosterone, Corlutina, Corluvite, Corporin, Crinone progesterone gel, Curretab, Cyclogest, Cyclogesterin, D4-Pregnene-3,20-dione, Delalutin, Duraprogen, Estima, Flavolutan, Fologenon, Gesterol, Gesterol 100, Gesterol 50, Gestiron, Gestone, Gestormone, Gestron, Gynlutin, Gynoluton, Gynolutone, Hormoflaveine, Hormoluton, Hydroxyprogesterone caproate, Hydroxyprogesterone caproic acid, Lingusorbs, Lipo-lutin, Lucorteum, Lucorteum sol, Lugesteron, Luteal hormone, Luteocrin normale, Luteodyn, Luteogan, Luteol, Luteopur, Luteosan, Luteostab, Luteovis, Luteum, Lutex, Lutidon, Lutociclina, Lutocuclin m, Lutocyclin, Lutocyclin m, Lutocylin, Lutocylol, Lutoform, Lutogyl, Lutren, Lutromone, Membrettes, Methylpregnone, MPA, Percutacrine, Percutacrine luteinique, Piaponon, Pranone, Pregn-4-en-3,20-dione, Pregn-4-ene-3,20-dione, Pregnene-3,20-dione, Pregnenedione, Primolut, Prochieve, Progeffik, Progekan, Progestan, Progestasert, Progesterol, Progesteronum, Progestin, Progestogel, Progestol, Progeston, Progestosol, Progestron, Progestronol, Projestaject, Prolets, Prolidon, Prolutin, Proluton, Prolutone, Prontogest, Protormone, Syngestrets, Synovex S, Syntolutan, Utrogest, Progesterone, (13 alpha,17 alpha)-(+-)-isomer, Progesterone, (17 alpha)-isomer, Progesterone, (9 beta,10 alpha)-isomer, luteol, progesterone |
| Esol Class | Moderately soluble |
| Functional Groups | CC(=O)C=C(C)C, CC(C)=O |
| Compound Name | Progesterone |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 1.0 |
| Exact Mass | 314.225 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 314.225 |
| Hydrogen Bond Acceptor Count | 2.0 |
| Molecular Weight | 314.5 |
| Gi Absorption | True |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 6.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic homopolycyclic compounds |
| Lipinski Rule Of 5 | True |
| Esol | -4.1618078 |
| Inchi | InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1 |
| Smiles | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C |
| Nring | 4.0 |
| Np Classifier Biosynthetic Pathway | Terpenoids |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | True |
| Taxonomy Direct Parent | Gluco/mineralocorticoids, progestogins and derivatives |
| Np Classifier Superclass | Steroids |
- 1. Outgoing r'ship
FOUND_INto/from Actinoscirpus Grossus (Plant) Rel Props:Reference:ISBN:9780387706375 - 2. Outgoing r'ship
FOUND_INto/from Alangium Ridleyi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 3. Outgoing r'ship
FOUND_INto/from Allium Cepa (Plant) Rel Props:Source_db:fooddb_chem_all - 4. Outgoing r'ship
FOUND_INto/from Boswellia Carterii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 5. Outgoing r'ship
FOUND_INto/from Hedysarum Denticulatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 6. Outgoing r'ship
FOUND_INto/from Helichrysum Nitens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 7. Outgoing r'ship
FOUND_INto/from Ligularia Songarica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 8. Outgoing r'ship
FOUND_INto/from Linum Usitatissimum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 9. Outgoing r'ship
FOUND_INto/from Lonicera Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 10. Outgoing r'ship
FOUND_INto/from Malus Domestica (Plant) Rel Props:Source_db:fooddb_chem_all - 11. Outgoing r'ship
FOUND_INto/from Oryza Sativa (Plant) Rel Props:Source_db:fooddb_chem_all - 12. Outgoing r'ship
FOUND_INto/from Pisum Sativum (Plant) Rel Props:Source_db:fooddb_chem_all - 13. Outgoing r'ship
FOUND_INto/from Senecio Nemorensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 14. Outgoing r'ship
FOUND_INto/from Solanum Tuberosum (Plant) Rel Props:Source_db:fooddb_chem_all - 15. Outgoing r'ship
FOUND_INto/from Trifolium Pratense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 16. Outgoing r'ship
FOUND_INto/from Vigna Radiata (Plant) Rel Props:Source_db:fooddb_chem_all