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Methyl 2,3-didehydroaspidospermidine-3-carboxylate

PubChem CID: 579873

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Compound Synonyms Vincadifformine, Methyl 2,3-didehydroaspidospermidine-3-carboxylate, BAS 00513802, Tabersonine, 6,7-dihydro-, Oprea1_228145, Oprea1_292497, CHEMBL1617045, GIGFIWJRTMBSRP-UHFFFAOYSA-N, HMS1607O09, BBL029154, STK094845, AKOS000635115, AKOS021618305, CCG-103082, Methyl 2,3-didehydroaspidospermidine-3-carboxylate #, Q15427938, Aspidospermidine-3-carboxylic acid, 2,3-didehydro-, methyl ester, (5.alpha.,12.beta.,19.alpha.)-, METHYL 3A-ETHYL-2,3,3A,4,6,11,12,13A-OCTAHYDRO-1H-INDOLIZINO[8,1-CD]CARBAZOLE-5-CARBOXYLATE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.6
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC3CCCC4CCC12C34
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)C=CNccC5CCC9)CC))CCCN6CC9)))))))))cccc6
Heavy Atom Count 25.0
Classyfire Class Aspidospermatan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC3CCCN4CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 629.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9-tetraene-10-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.5
Gsk 4 400 Rule True
Molecular Formula C21H26N2O2
Scaffold Graph Node Bond Level C1=C2Nc3ccccc3C23CCN2CCCC(C1)C23
Prediction Swissadme 1.0
Inchi Key GIGFIWJRTMBSRP-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5714285714285714
Logs -5.621
Rotatable Bond Count 3.0
Logd 4.437
Synonyms (-)-vincadifformine
Esol Class Moderately soluble
Functional Groups CN(C)C, cNC(C)=C(C)C(=O)OC
Compound Name Methyl 2,3-didehydroaspidospermidine-3-carboxylate
Prediction Hob Swissadme 1.0
Exact Mass 338.199
Formal Charge 0.0
Monoisotopic Mass 338.199
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 338.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.1103962
Inchi InChI=1S/C21H26N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-5,7-8,19,22H,3,6,9-13H2,1-2H3
Smiles CCC12CCCN3C1C4(CC3)C5=CC=CC=C5NC4=C(C2)C(=O)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9770972795006
  • 2. Outgoing r'ship FOUND_IN to/from Vinca Erecta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all