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Deoxyvobtusine

PubChem CID: 56673596

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Compound Synonyms Deoxyvobtusine, methyl (1R,1'S,7'S,11'R,12R,13'R,16S,17S,22R,24'S,25'R)-19'-methoxyspiro(15-oxa-8,19-diazahexacyclo(10.9.1.01,9.02,7.012,16.019,22)docosa-2,4,6,9-tetraene-17,15'-8-oxa-4,17-diazaheptacyclo(11.10.1.11,4.07,11.017,24.018,23.011,25)pentacosa-18(23),19,21-triene)-10-carboxylate, methyl (1R,1'S,7'S,11'R,12R,13'R,16S,17S,22R,24'S,25'R)-19'-methoxyspiro[15-oxa-8,19-diazahexacyclo[10.9.1.01,9.02,7.012,16.019,22]docosa-2,4,6,9-tetraene-17,15'-8-oxa-4,17-diazaheptacyclo[11.10.1.11,4.07,11.017,24.018,23.011,25]pentacosa-18(23),19,21-triene]-10-carboxylate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 75.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC34CCCC3C3(CC5CC67CCCC6CCC6CCC8(C9CCCCC9C(C3)C58)C67)CC3CCC12C34
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)C=CNcc[C@]5[C@@H][C@@]C9)CCO[C@H]5[C@]CN9CC%12))))C[C@@H]C[C@]CCO[C@H]5CCN[C@@H]9[C@@][C@H]%13NC%17)ccOC))cccc96))))))))CC5)))))))))))))))))))))))cccc6
Heavy Atom Count 52.0
Classyfire Class Aspidospermatan-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC34CCOC3C3(CC5CC67CCOC6CCN6CCC8(C9CCCCC9N(C3)C58)C67)CN3CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 1620.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 11.0
Uniprot Id O42275, P81908
Iupac Name methyl (1R,1'S,7'S,11'R,12R,13'R,16S,17S,22R,24'S,25'R)-19'-methoxyspiro[15-oxa-8,19-diazahexacyclo[10.9.1.01,9.02,7.012,16.019,22]docosa-2,4,6,9-tetraene-17,15'-8-oxa-4,17-diazaheptacyclo[11.10.1.11,4.07,11.017,24.018,23.011,25]pentacosa-18(23),19,21-triene]-10-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.8
Gsk 4 400 Rule False
Molecular Formula C43H50N4O5
Scaffold Graph Node Bond Level C1=C2Nc3ccccc3C23CCN2CC4(CC5CC67CCOC6CCN6CCC8(c9ccccc9N(C4)C58)C67)C4OCCC4(C1)C23
Inchi Key IWNZQRZTZRLAFI-AYMQSLGUSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 3.0
Synonyms deoxyvobtusine
Esol Class Poorly soluble
Functional Groups CN(C)C, COC, cN(C)C, cNC(C)=C(C)C(=O)OC, cOC
Compound Name Deoxyvobtusine
Exact Mass 702.378
Formal Charge 0.0
Monoisotopic Mass 702.378
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 702.9
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C43H50N4O5/c1-49-30-9-5-7-28-32(30)47-24-39(20-25-21-40-13-18-51-31(40)10-15-45-16-12-43(28,34(25)47)36(40)45)23-46-17-11-42-27-6-3-4-8-29(27)44-33(42)26(35(48)50-2)22-41(37(42)46)14-19-52-38(39)41/h3-9,25,31,34,36-38,44H,10-24H2,1-2H3/t25-,31+,34+,36+,37+,38+,39+,40-,41+,42+,43+/m1/s1
Smiles COC1=CC=CC2=C1N3C[C@]4(C[C@H]5[C@H]3[C@]26CCN7[C@H]6[C@@]8(C5)CCO[C@H]8CC7)CN9CC[C@@]12[C@@H]9[C@@]3([C@H]4OCC3)CC(=C1NC1=CC=CC=C21)C(=O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Voacanga Foetida (Plant) Rel Props:Reference:ISBN:9780387706375