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Sinococuline

PubChem CID: 5489400

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Compound Synonyms Sinococuline, 109351-36-2, ALKALOID FK1000, J5624PB437, (6beta,7beta,9alpha,13alpha)-8,14-Didehydro-3,8-dimethoxymorphinan-4,6,7-triol, CHEMBL524026, (1S,9S,12S,13S)-4,11-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10-tetraene-3,12,13-triol, FK-1000, Morphinan-4,6,7-triol, 8,14-didehydro-3,8-dimethoxy-, (6beta,7beta,9alpha,13alpha)-, (1S,9S,12S,13S)-4,11-DIMETHOXY-17-AZATETRACYCLO(7.5.3.0^(1,10).0^(2,7))HEPTADECA-2(7),3,5,10-TETRAENE-3,12,13-TRIOL, (6.BETA.,7.BETA.,9.ALPHA.,13.ALPHA.)-8,14-DIDEHYDRO-3,8-DIMETHOXYMORPHINAN-4,6,7-TRIOL, MORPHINAN-4,6,7-TRIOL, 8,14-DIDEHYDRO-3,8-DIMETHOXY-, (6.BETA.,7.BETA.,9.ALPHA.,13.ALPHA.)-, (1S,9S,12S,13S)-4,11-dimethoxy-17-azatetracyclo(7.5.3.01,10.02,7)heptadeca-2(7),3,5,10-tetraene-3,12,13-triol, SCHEMBL166476, UNII-J5624PB437, DTXSID00911127, BDBM50260779, HY-N11096, AKOS040763319, DA-77854, F92832, Q15427859
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 91.2
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2C(C1)CC1CCCC23CCCCC13
Np Classifier Class Morphinan alkaloids
Deep Smiles COC=C[C@H]NCC[C@]6C[C@@H][C@@H]%10O))O)))ccC8)cccc6O))OC
Heavy Atom Count 24.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level C1CCC2C(C1)CC1NCCC23CCCCC13
Isotope Atom Count 0.0
Molecular Complexity 538.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id P41143, P35372, P41145
Iupac Name (1S,9S,12S,13S)-4,11-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10-tetraene-3,12,13-triol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT271
Xlogp -0.1
Gsk 4 400 Rule True
Molecular Formula C18H23NO5
Scaffold Graph Node Bond Level C1=C2C3Cc4ccccc4C2(CCC1)CCN3
Prediction Swissadme 1.0
Inchi Key MFKPWBJXKCSPGK-KNORBDTNSA-N
Silicos It Class Soluble
Fcsp3 0.5555555555555556
Logs -1.344
Rotatable Bond Count 2.0
Logd 0.792
Synonyms sinococuline
Esol Class Very soluble
Functional Groups CNC, CO, COC(C)=C(C)C, cO, cOC
Compound Name Sinococuline
Prediction Hob Swissadme 1.0
Exact Mass 333.158
Formal Charge 0.0
Monoisotopic Mass 333.158
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 333.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.8969808000000001
Inchi InChI=1S/C18H23NO5/c1-23-12-4-3-9-7-10-14-17(24-2)15(21)11(20)8-18(14,5-6-19-10)13(9)16(12)22/h3-4,10-11,15,19-22H,5-8H2,1-2H3/t10-,11-,15-,18-/m0/s1
Smiles COC1=C(C2=C(C[C@H]3C4=C([C@H]([C@H](C[C@]42CCN3)O)O)OC)C=C1)O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Cocculus Orbiculatus (Plant) Rel Props:Reference:ISBN:9788172362133
  • 2. Outgoing r'ship FOUND_IN to/from Stephania Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all