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Neopine

PubChem CID: 5462437

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Compound Synonyms Neopine, Neopin, 467-14-1, UNII-TM43JB0IA8, .beta.-Codeine, TM43JB0IA8, beta-Codeine, NEOPINE [MI], EINECS 207-387-7, DTXSID80196910, (4R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,6,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol, (5alpha,6alpha)-8,14-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol, (5.ALPHA.,6.ALPHA.)-8,14-DIDEHYDRO-4,5-EPOXY-3-METHOXY-17-METHYLMORPHINAN-6-OL, Morphinan-6.alpha.-ol, 8,14-didehydro-4,5.alpha.-epoxy-3-methoxy-17-methyl-, Spectrum2_001745, Spectrum3_001011, Morphinan-6-ol, 8,14-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-, (4R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,6,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinolin-7-ol, Spectrum4_001139, Spectrum5_001754, BSPBio_002761, KBioGR_001657, SCHEMBL679477, SPBio_001850, CHEBI:7509, 8,14-Didehydro-4,5.alpha.-epoxy-3-methoxy-17-methylmorphinan-6.alpha.-ol, KBio3_001981, DTXCID20119401, (4R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,6,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinoline-7-ol, (4R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,6,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol, CCG-39441, NS00031628, C09594, BRD-K34252131-001-02-0, Q27107515, 8,14-Didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol, Morphinan-6alpha-ol, 8,14-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl-, Morphinan-6-ol, 8,14-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC45C(CCCC34)CC(C1)C25
Np Classifier Class Isoquinoline alkaloids, Morphinan alkaloids
Deep Smiles COcccccc6O[C@@H][C@]5CCN[C@H]C%11)C6=CC[C@@H]%10O))))))C
Heavy Atom Count 22.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level C1CC2CC3NCCC45C(CCCC34)OC(C1)C25
Isotope Atom Count 0.0
Molecular Complexity 520.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (4R,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,6,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 1.6
Gsk 4 400 Rule True
Molecular Formula C18H21NO3
Scaffold Graph Node Bond Level C1=C2C3Cc4cccc5c4C2(CCN3)C(CC1)O5
Prediction Swissadme 1.0
Inchi Key NNDKZTBFZTWKLA-QISBLDNZSA-N
Silicos It Class Soluble
Fcsp3 0.5555555555555556
Logs -1.93
Rotatable Bond Count 1.0
Logd 1.688
Synonyms neopine
Esol Class Soluble
Functional Groups CC=C(C)C, CN(C)C, CO, cOC
Compound Name Neopine
Prediction Hob Swissadme 1.0
Exact Mass 299.152
Formal Charge 0.0
Monoisotopic Mass 299.152
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 299.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.833612181818182
Inchi InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-4,6,12-13,17,20H,5,7-9H2,1-2H3/t12-,13+,17+,18+/m1/s1
Smiles CN1CC[C@]23[C@@H]4[C@H](CC=C2[C@H]1CC5=C3C(=C(C=C5)OC)O4)O
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Microstigma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Aquilaria Agallochum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Chrozophora Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Papaver Bracteatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Papaver Rhoeas (Plant) Rel Props:Reference:ISBN:9788185042053
  • 6. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all