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(7R,12S,13R)-13-[(S)-hydroxy(phenyl)methyl]-7-phenyl-1,6,10-triazabicyclo[10.2.1]pentadecane-9,14-dione

PubChem CID: 5458904

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Compound Synonyms Caesalpinine A, NSC378247
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 81.7
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC2CC(CCCCCC(C3CCCCC3)C1)C(C)C2CC1CCCCC1
Np Classifier Class Polyamines
Deep Smiles O=CNC[C@H]CNC=O)[C@H]5[C@@H]cccccc6))))))O))))CCCCN[C@H]C%13)cccccc6
Heavy Atom Count 31.0
Classyfire Class Peptidomimetics
Scaffold Graph Node Level OC1CC(C2CCCCC2)NCCCCN2CC(CN1)C(CC1CCCCC1)C2O
Classyfire Subclass Hybrid peptides
Isotope Atom Count 0.0
Molecular Complexity 601.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (7R,12S,13R)-13-[(S)-hydroxy(phenyl)methyl]-7-phenyl-1,6,10-triazabicyclo[10.2.1]pentadecane-9,14-dione
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 2.0
Gsk 4 400 Rule False
Molecular Formula C25H31N3O3
Scaffold Graph Node Bond Level O=C1CC(c2ccccc2)NCCCCN2CC(CN1)C(Cc1ccccc1)C2=O
Inchi Key SHBCCFGHZDXOET-XWVZOOPGSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 3.0
Synonyms caesalpinine a
Esol Class Soluble
Functional Groups CN(C)C(C)=O, CNC, CNC(C)=O, CO
Compound Name (7R,12S,13R)-13-[(S)-hydroxy(phenyl)methyl]-7-phenyl-1,6,10-triazabicyclo[10.2.1]pentadecane-9,14-dione
Exact Mass 421.237
Formal Charge 0.0
Monoisotopic Mass 421.237
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 421.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C25H31N3O3/c29-22-15-21(18-9-3-1-4-10-18)26-13-7-8-14-28-17-20(16-27-22)23(25(28)31)24(30)19-11-5-2-6-12-19/h1-6,9-12,20-21,23-24,26,30H,7-8,13-17H2,(H,27,29)/t20-,21+,23+,24+/m0/s1
Smiles C1CCN2C[C@H](CNC(=O)C[C@@H](NC1)C3=CC=CC=C3)[C@@H](C2=O)[C@@H](C4=CC=CC=C4)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Caesalpinia Digyna (Plant) Rel Props:Reference:ISBN:9788185042114