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Clausenolide

PubChem CID: 5458600

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Compound Synonyms CLAUSENOLIDE, DTXSID70420014, 71899-58-6, (1R,2R,4S,7S,8S,10S,12R,13S)-7-(furan-3-yl)-10,13-dihydroxy-1,8,12,13,15,15-hexamethyl-3,6,14-trioxapentacyclo(9.7.0.02,4.02,8.012,16)octadecane-5,18-dione, (1R,2R,4S,7S,8S,10S,12R,13S)-7-(furan-3-yl)-10,13-dihydroxy-1,8,12,13,15,15-hexamethyl-3,6,14-trioxapentacyclo[9.7.0.02,4.02,8.012,16]octadecane-5,18-dione, DTXCID50370861, NSC294578
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 119.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC(C2CCCC2)C2CCC3C4CCCC4CC(C)C3C23CC13
Np Classifier Class Limonoids
Deep Smiles O[C@H]C[C@@]C)[C@@H]OC=O)[C@@H][C@@]6[C@]C%10[C@]C)CCC6=O)))CO[C@]5C)O)))C)C)))))C))O3)))))ccocc5
Heavy Atom Count 33.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level OC1CC2COCC2C2CCC3C(C4CCOC4)OC(O)C4OC34C12
Classyfire Subclass Steroid lactones
Isotope Atom Count 0.0
Molecular Complexity 949.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name (1R,2R,4S,7S,8S,10S,12R,13S)-7-(furan-3-yl)-10,13-dihydroxy-1,8,12,13,15,15-hexamethyl-3,6,14-trioxapentacyclo[9.7.0.02,4.02,8.012,16]octadecane-5,18-dione
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.1
Gsk 4 400 Rule False
Molecular Formula C25H32O8
Scaffold Graph Node Bond Level O=C1OC(c2ccoc2)C2CCC3C4COCC4CC(=O)C3C23OC13
Inchi Key ABUJYLRTXBVIRH-KNFPJBQWSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 1.0
Synonyms clausenolide
Esol Class Soluble
Functional Groups CC(C)=O, CO, CO[C@@](C)(C)O, C[C@]12CCOC(=O)[C@H]1O2, coc
Compound Name Clausenolide
Exact Mass 460.21
Formal Charge 0.0
Monoisotopic Mass 460.21
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 460.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C25H32O8/c1-20(2)14-9-15(27)23(5)16(22(14,4)24(6,29)33-20)13(26)10-21(3)17(12-7-8-30-11-12)31-19(28)18-25(21,23)32-18/h7-8,11,13-14,16-18,26,29H,9-10H2,1-6H3/t13-,14?,16?,17-,18+,21-,22-,23+,24-,25+/m0/s1
Smiles C[C@@]12C[C@@H](C3[C@@]4(C(CC(=O)[C@]3([C@@]15[C@H](O5)C(=O)O[C@H]2C6=COC=C6)C)C(O[C@]4(C)O)(C)C)C)O
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Triterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Clausena Anisata (Plant) Rel Props:Reference:ISBN:9788172362133
  • 2. Outgoing r'ship FOUND_IN to/from Clausena Heptaphylla (Plant) Rel Props:Reference:ISBN:9788172360481; ISBN:9788172362133; ISBN:9788185042084