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1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

PubChem CID: 5418

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Compound Synonyms TETRAHYDROPAPAVERINE, 13074-31-2, 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, 1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline, Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (+/-)-Tetrahydropapaverine, 1,2,3,4-Tetrahydropapaverine, Tetrahydropapaverin, 1-((3,4-Dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline, EINECS 235-968-5, Papaverine, 1,2,3,4-tetrahydro-, (+/-)-N-Norlaudanosine, TimTec1_002724, Oprea1_802595, MLS006011806, CHEMBL160919, SCHEMBL1076975, CHEBI:195380, DTXSID701018689, HMS1541L18, KUC103648N, ALBB-025297, CCG-26031, STK664098, AKOS003335113, AC-7467, NCGC00163633-01, NCGC00163633-02, NCGC00163633-03, SMR001483237, DB-049924, DB-225596, NS00040727, UNM000011058001, EN300-177753, A828340, SR-01000639215, SR-01000639215-3, BRD-A91831168-003-02-5, 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline #, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, R-TETRAHYDROPAPAVERINE, isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydroiodide
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(CC2CCCC3CCCCC32)CC1
Np Classifier Class Isoquinoline alkaloids, Tetrahydroisoquinoline alkaloids
Deep Smiles COcccccc6OC)))))CCNCCcc6ccOC))cc6)OC
Heavy Atom Count 25.0
Classyfire Class Isoquinolines and derivatives
Scaffold Graph Node Level C1CCC(CC2NCCC3CCCCC32)CC1
Classyfire Subclass Benzylisoquinolines
Isotope Atom Count 0.0
Molecular Complexity 407.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.2
Gsk 4 400 Rule True
Molecular Formula C20H25NO4
Scaffold Graph Node Bond Level c1ccc(CC2NCCc3ccccc32)cc1
Inchi Key YXWQTVWJNHKSCC-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 6.0
Synonyms tetrahydropapaverine
Esol Class Soluble
Functional Groups CNC, cOC
Compound Name 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
Exact Mass 343.178
Formal Charge 0.0
Monoisotopic Mass 343.178
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 343.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H25NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-6,10-12,16,21H,7-9H2,1-4H3
Smiles COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Reference:ISBN:9788172363130